UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T09E11.4	T09E11.4	0	chrI 12,361,669	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
2	tag-256	ZK637.3	n/a	chrIII 8,892,125	C. elegans TAG-256 protein ; contains similarity to Drosophila melanogaster Flybase gene name is CG7739-PA;; FLYBASE:CG7739
3	cyp-33C4	F44C8.1	n/a	chrV 2,237,058	C. elegans CYP-33C4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
4	T09F5.1	T09F5.1	n/a	chrV 15,149,875	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
5	F32D8.4	F32D8.4	n/a	chrV 10,892,425	F32D8.4 is homologous to Yip1p, an essential Golgi membrane protein in S. cerevisiae that specifically binds the transport GTPases Ypt1p and Ypt31p, as well as Yop1p (the yeast homolog of human ADENOMATOUS POLYPOSIS COLI 1); F32D8.4 is also homologous to the Golgi membrane protein SB140 of H. sapiens, and contains a glutamine/asparagine-rich domain.
6	pld-1	C04G6.3	n/a	chrII 5,087,755	C. elegans PLD-1 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF00614 (Phospholipase D Active site motif) (2), PF00787 (PX domain) contains similarity to Interpro domains IPR016555 (Phospholipase D, eukaryota), IPR001683 (Phox-like), IPR001849 (Pleckstrin-like), IPR001736 (Phospholipase D/Transphosphatidylase), IPR015679 (Phospholipase D)
7	srd-34	F32G8.1	n/a	chrV 10,548,271	C. elegans SRD-34 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
8	srd-4	ZK863.5	n/a	chrV 12,185,574	C. elegans SRD-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
9	ZC373.3	ZC373.3	n/a	chrX 10,061,060	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
10	W04A4.5	W04A4.5	n/a	chrI 13,669,210	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
11	F14H12.8	F14H12.8	n/a	chrX 4,363,765
12	F42A9.6	F42A9.6	n/a	chrIV 8,610,474
13	ZK643.5	ZK643.5	n/a	chrIII 8,954,457	contains similarity to Homo sapiens RNA binding motif protein 25; ENSEMBL:ENSP00000261973
14	ZK328.4	ZK328.4	n/a	chrIII 6,007,663	contains similarity to Interpro domain IPR006640 (Protein of unknown function SprT)
15	C50H2.4	C50H2.4	n/a	chrV 9,917,432	contains similarity to Arabidopsis thaliana Putative cytochrome P450.; TR:Q9LQ26
16	fbxa-184	F45C12.8	n/a	chrII 1,710,841	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	lgc-14	T01H10.2	n/a	chrX 12,112,417	C. elegans LGC-14 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
18	C04E7.3	C04E7.3	n/a	chrX 345,208	contains similarity to Homo sapiens inner centromere protein antigens 135/155kDa isoform 2; ENSEMBL:ENSP00000278849
19	nhr-55	T01G6.7	n/a	chrV 479,428	nhr-55 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
20	C06E7.4	C06E7.4	n/a	chrIV 5,855,392	contains similarity to Human cytomegalovirus Protein UL53 (Protein HFRF2).; SW:P16794
21	aat-8	F28F9.4	n/a	chrIV 3,863,573	aat-8 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-8 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-8 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
22	emb-5	T04A8.14	n/a	chrIII 4,717,943	emb-5 encodes the C. elegans ortholog of the Spt6 family of RNA polymerase II transcription elongation factors; first identified in screens for temperature-sensitive embryonic lethal mutations, emb-5 is required for the correct timing of the second E (endoderm)-cell division in the early embryo and thus, for normal embryonic gastrulation; in addition, emb-5 activity is required postembryonically for proper gonad development; in yeast two-hybrid studies, EMB-5 interacts with the intracellular domains of LIN-12 and GLP-1, suggesting that EMB-5 functions as a positive downstream effector in Notch-like signaling pathways during C. elegans development; emb-5 mRNA is most abundant during embryonic stages, with lower levels apparent during the L1-L3 larval stages, and even lower levels observed during L4.
23	T28F2.7	T28F2.7	n/a	chrI 3,658,340	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR001873 (Na+ channel, amiloride-sensitive)
24	T05E7.4	T05E7.4	n/a	chrI 6,193,727
25	C05C8.5	C05C8.5	n/a	chrV 7,233,733	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
26	fbxb-7	Y20C6A.2	n/a	chrV 17,378,293	C. elegans FBXB-7 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
27	str-73	F26D2.1	n/a	chrV 16,431,023	C. elegans STR-73 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	T10B11.4	T10B11.4	n/a	chrI 6,938,560
29	sago-1	K12B6.1	n/a	chrV 6,306,024	sago-1 encodes an Argonaute homolog that is partially required for the amplification phase of RNAi responses; a multiply mutant strain (MAGO), consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894), F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, is completely resistant to both germline and somatic RNAi; sago-1 is genetically redundant with ppw-1 and sago-2, with any one of these genes being able to transgenically partially restore the deficiency of MAGO worms; GFP-tagged SAGO-1 binds small secondary siRNAs produced by RNAi against GFP; MAGO is not transgenically rescued by rde-1; strains overexpressing GFP::SAGO-1 exhibited an enhanced level of RNAi overall, suggesting that SAGO-1 and its congeners are rate-limiting in vivo for RNAi.
30	F46H5.5	F46H5.5	n/a	chrX 7,256,401
31	T06C12.8	T06C12.8	3e-124	chrV 15,883,366	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
32	C09B9.3	C09B9.3	n/a	chrIV 5,025,066	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
33	F28D1.9	F28D1.9	n/a	chrIV 12,395,382	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
34	F29C4.6	F29C4.6	n/a	chrIV 120,551	contains similarity to Pfam domain PF01171 PP-loop family contains similarity to Interpro domains IPR011063 (PP-loop), IPR012089 (PP-loop ATPase, YdaO-related), IPR000541 (Protein of unknown function UPF0021), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
35	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
36	ech-5	F56B3.5	n/a	chrIV 798,439	C. elegans ECH-5 protein; contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
37	him-17	T09E8.2	n/a	chrV 13,178,423	him-17 encodes a protein with no obvious non-nematode homologs that localizes to chromatin in germline nuclei, and that is required for double-stranded break (DSB) formation, chiasmata, crossovers, and genetic recombination during meiosis, but is dispensable for homolog pairing and synapsis, spo-11 germline transcription, or the conversion of DSBs into chiasmata; HIM-17 is also required for normal organization of meiotic stages in the germline, and to promote its orderly transistion from (potentially tumorous) mitosis to meiosis; moreover, HIM-17 is required for normal dimethylation of lysine 9 residues on H3 histones in meiotic prophase chromosomes from early pachytene onward, with null him-17(ok424) mutants showing greatly reduced or delayed dimethylation in both hermaphrodite and male germlines; HIM-17 cooperates with GLP-1 to promote meiotic entry, and with EGO-1 to promote germline viability; HIM-17 has six THAP and THAP-like domains, a domain type also found in CDC-14B, CTB-1, GON-14, LIN-15A, LIN-15B, and LIN-36, along with ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1; missense or truncating mutations of HIM-17's THAP and THAP-like domains cause partial loss of function, implying that the domains collectively and partially contribute to HIM-17 activity; of the C. elegans genes encoding THAP or THAP-like domains, at least four (lin-15A, lin-15B, lin-36, and him-17) interact genetically with lin-35/Rb.
38	F45C12.16	F45C12.16	n/a	chrII 1,737,908	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
39	srsx-21	R07B5.5	n/a	chrV 9,838,755	C. elegans SRSX-21 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
40	qua-1	T05C12.10	n/a	chrII 8,201,326	qua-1 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Qua domain, a 5W repeat, an extended region of low-complexity sequence, and a Hint/Hog domain; QUA-1 is conserved among nematodes from Caenorhabditis to Brugia; QUA-1 is expressed prior to molting in hyp1 to hyp11 hypodermal cells, but not in seam cells, and ceases to be expressed after each molting cycle or in gravid adults no longer molting; QUA-1 is strongly required for normal molting, with lethal molting defects in qua-1 mutants and severe defects in qua-1(RNAi) animals; similar molting defects in RNAi of ptr-4 and ptr-23 (encoding Dispatched homologs) suggest that PTR-4 and PTR-23 may export QUA-1 from hypodermal cells synthesizing it; other sites of QUA-1 expression include intestinal and rectal cells, excretory duct and pore cells, sensilla support cells, the P cell lineage in L1, body wall muscle, and the adult reproductive system; QUA-1 is also required for normal adult alae formation, growth to full size, cuticle adhesion, locomotion, and male tail development; the Hint/Hog domain is predicted to cut QUA-1 into two halves and then covalently link cholesterol to the C-terminus of the Qua domain; the Qua domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and the Qua domain has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; both Qua and Hint/Hog domains are required for transgenic rescue of a lethal qua-1 allele; defects in both qua-1 mutants and qua-1(RNAi) animals; all of QUA-1's functions may reflect common defects in cholesterol-dependent hedgehog-like signalling.
41	C06E1.8	C06E1.8	n/a	chrIII 8,596,527	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
42	R11G1.2	R11G1.2	n/a	chrX 3,653,706
43	C31E10.8	C31E10.8	n/a	chrX 14,007,275	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR011046 (WD40 repeat-like), IPR002011 (Receptor tyrosine kinase, class II, conserved site)
44	fbxb-5	F45C12.14	n/a	chrII 1,721,873	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
45	C14C6.8	C14C6.8	n/a	chrV 552,129	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
46	ZC443.1	ZC443.1	n/a	chrV 12,809,256	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
47	math-36	R52.8	n/a	chrII 2,118,724	C. elegans MATH-36 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
48	T02B5.3	T02B5.3	n/a	chrV 14,159,248	contains similarity to Pfam domain PF00135 (Carboxylesterases)
49	nhr-133	F44C8.8	n/a	chrV 2,211,309	C. elegans NHR-133 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
50	F36G9.12	F36G9.12	0.00000009	chrV 15,980,154	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR001356 (Homeobox), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)