UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srg-28	T09D3.2	0	chrV 5,335,592	C. elegans SRG-28 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	ZC376.1	ZC376.1	n/a	chrV 14,179,216	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
4	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	F22G12.1	F22G12.1	n/a	chrI 13,140,448	contains similarity to Interpro domain IPR000423 (Flagellar protein FlgJ type-1)
6	ceh-33	C10G8.7	n/a	chrV 5,323,911	ceh-33 encodes a Six/sine oculis class homeodomain transcription factor; preliminary RNAi experiments suggest that CEH-33 activity may be required for gonad development; a ceh-33::gfp reporter shows very weak pharyngeal expression in late embryos and early larvae.
7	col-164	T21D9.1	n/a	chrX 2,094,123	C. elegans COL-164 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
8	E02C12.9	E02C12.9	n/a	chrV 9,374,371	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
9	srh-282	T21D12.5	n/a	chrIV 272,850	C. elegans SRH-282 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	Y57G11B.2	Y57G11B.2	n/a	chrIV 14,566,202	contains similarity to Guillardia theta Hypothetical protein orf176 from chromosome 3.; TR:Q98SC3
11	R12C12.3	R12C12.3	n/a	chrII 6,030,297	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002184 (Serpentine beta receptor), IPR000276 (GPCR, rhodopsin-like)
12	sre-53	C50E10.3	n/a	chrII 12,322,214	C. elegans SRE-53 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
13	fbxb-65	C43D7.2	n/a	chrV 19,330,120	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
14	T22H9.1	T22H9.1	n/a	chrV 361,718	contains similarity to Pfam domain PF06102 Domain of unknown function (DUF947) contains similarity to Interpro domain IPR009292 (Protein of unknown function DUF947)
15	C25E10.7	C25E10.7	n/a	chrV 9,050,528	C25E10.7 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C25E10.7 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C25E10.7 has no obvious function in mass RNAi assays.
16	T09E11.6	T09E11.6	n/a	chrI 12,367,467	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
17	ZK1307.4	ZK1307.4	n/a	chrII 9,651,306	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
18	B0041.5	B0041.5	n/a	chrI 4,649,524	contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
19	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
20	gcy-33	F57F5.2	n/a	chrV 11,998,799	gcy-33 encodes a soluble guanylyl cyclase; a gcy-33::GFP reporter is expressed in the ciliated BAG head sensory neurons.
21	T07C12.8	T07C12.8	n/a	chrV 9,954,532	contains similarity to Interpro domain IPR000998 (MAM)
22	F54E4.2	F54E4.2	n/a	chrX 14,627,172	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
23	srd-27	T26E4.12	n/a	chrV 15,803,891	C. elegans SRD-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	nhr-217	T09E11.2	n/a	chrI 12,341,975	C. elegans NHR-217 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
25	wht-3	C16C10.12	n/a	chrIII 4,149,469	C16C10.12 encodes an ATP-binding cassette (ABC) transporter; C16C10.12 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1.
26	atf-6	F45E6.2	n/a	chrX 12,482,840	atf-6 is an ortholog of mammalian ATF6alpha, a proximal sensor required for the unfolded protein response (UPR) in the endoplasmic reticulum (ER); ATF6alpha is a transmembrane protein, with a bZIP transcription factor domain in its cytosolic amino terminus that is released and activated by proteolytic cleavage upon ER stress; either ire-1 or xbp-1 deletions are synthetically lethal with atf-6 or pek-1 deletions, producing arrest in L2 larvae; RNAi of Y56A3A.2 (a S2P protease homolog) is synthetically lethal with ire-1(RNAi), consistent with the hypothesis that Y56A3A.2 cleaves ATF-6; atf-6 regulates few genes that are transcriptionally induced by UPR, but regulates roughly one-quarter of genes that require UPR constitutively; pdr-1 transcripts are strongly upregulated in a atf-6(ok551) mutant background, but atf-6(ok551);pdr-1(lg103) double mutants have a grossly normal phenotype ; atf-6 is dispensable for proper localization of GLR-1 glutamate receptors.
27	clec-259	M162.1	n/a	chrV 19,786,034	C. elegans CLEC-259 protein; contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR007233 (Sybindin-like protein), IPR008985 (Concanavalin A-like lectin/glucanase)
28	ceh-31	C33D12.1	n/a	chrX 3,069,626	ceh-31 encodes a protein containing a homeobox domain.
29	ubq-2	ZK1010.1	n/a	chrIII 12,978,145	ubq-2 encodes a bifunctional protein that contains two domains; an N-terminal ubiquitin peptide, and a C-terminal large ribosomal subunit protein L40 peptide.
30	phy-3	T20B3.7	n/a	chrV 16,836,164	C. elegans PHY-3 protein; contains similarity to Pfam domain PF03171 2OG-Fe(II) oxygenase superfamily contains similarity to Interpro domains IPR006620 (Prolyl 4-hydroxylase, alpha subunit), IPR017853 (Glycoside hydrolase, catalytic core), IPR005123 (2OG-Fe(II) oxygenase)
31	srw-108	R11G11.5	n/a	chrV 528,386	C. elegans SRW-108 protein ;
32	T22D1.11	T22D1.11	n/a	chrIV 6,927,277	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
33	C32E8.3	C32E8.3	n/a	chrI 3,787,036	contains similarity to Pfam domain PF05517 p25-alpha contains similarity to Interpro domain IPR008907 (P25-alpha)
34	B0336.3	B0336.3	n/a	chrIII 5,713,118	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domains IPR000571 (Zinc finger, CCCH-type), IPR000694 (Proline-rich region), IPR000504 (RNA recognition motif, RNP-1), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR001984 (Peptidase S16, Lon protease)
35	srz-14	K05D4.3	n/a	chrV 16,184,163	C. elegans SRZ-14 protein ;
36	C47E8.3	C47E8.3	n/a	chrV 14,681,957	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
37	T16A9.4	T16A9.4	n/a	chrV 14,218,017	T16A9.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T16A9.4 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
38	C02E7.10	C02E7.10	n/a	chrV 4,931,908
39	C01H6.2	C01H6.2	n/a	chrI 7,206,143	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
40	Y57A10C.10	Y57A10C.10	n/a	chrII 12,440,350	contains similarity to Pfam domain PF01838 (Domain of unknown function DUF40)
41	srh-169	C49G7.2	n/a	chrV 4,048,582	C. elegans SRH-169 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	srh-279	F11A5.2	n/a	chrV 16,193,941	C. elegans SRH-279 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	F53G12.4	F53G12.4	n/a	chrI 135,809
44	sre-21	C47A10.4	n/a	chrV 17,771,397	C47A10.4 is orthologous to the human gene ALBINISM, OCULAR, TYPE I (OA1; OMIM:300500), which when mutated leads to Nettleship-Falls type ocular albinism.
45	acr-3	K11G12.7	n/a	chrX 6,711,143	acr-3 encodes a non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; ACR-3 functions as a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-38, an nAChR alpha subunit, the resulting hetero-oligomer can form levamisole-gated channels; ACR-3 is a member of the UNC-29-like group of nAChR subunits.
46	T09B9.2	T09B9.2	n/a	chrX 9,763,139	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter), IPR004745 (Na(+)-dependent inorganic phosphate cotransporter)
47	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
48	F36H12.15	F36H12.15	n/a	chrIV 5,268,338
49	T03G11.5	T03G11.5	n/a	chrX 5,168,923
50	srw-59	H24D24.1	n/a	chrV 15,950,332	C. elegans SRW-59 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)