UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T08G5.1	T08G5.1	9.999999999999999e-123	chrV 14,019,744	contains similarity to Saccharomyces cerevisiae Protein that may function as a cochaperone, as suggested by the presence of a DnaJ-like domain; SGD:YNL227C
2	srsx-11	C13D9.4	n/a	chrV 4,978,533	C. elegans SRSX-11 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
3	srg-4	T12A2.12	n/a	chrIII 6,261,094	C. elegans SRG-4 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
4	srw-98	K04F1.3	n/a	chrV 1,677,402	C. elegans SRW-98 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
5	fkh-10	C25A1.2	n/a	chrI 10,164,375	fkh-10 encodes one of 15 forkhead transcriptional regulators encoded by the C. elegans genome; by homology, FKH-10 is predicted to function as a transcription factor that regulates gene expression during development; however, as loss of fkh-10 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKH-10 in C. elegans development and/or behavior is not yet known; nevertheless, reporter gene studies indicate that throughout larval and adult stages, fkh-10 expression is detected almost exclusively in six pairs of neuronal nuclei near the terminal bulb of the pharynx, suggesting that FKH-10 may have a specific function in neuronal differentiation.
6	R13.2	R13.2	n/a	chrIV 10,826,996	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
7	T24E12.2	T24E12.2	n/a	chrII 3,783,547
8	srx-7	C14C6.1	n/a	chrV 561,828	C. elegans SRX-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
9	C13A2.5	C13A2.5	n/a	chrV 7,277,113	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
10	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	clec-227	F08H9.5	n/a	chrV 14,473,432	C. elegans CLEC-227 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	clec-50	W04E12.8	n/a	chrV 19,749,271	C. elegans CLEC-50 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR000480 (Glutelin), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
13	R08H2.10	R08H2.10	n/a	chrV 15,373,870	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
14	ver-1	T17A3.1	n/a	chrIII 160,182	C. elegans VER-1 protein; contains similarity to Pfam domains PF00047 (Immunoglobulin domain) (2), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF07679 (Immunoglobulin I-set domain) (2)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR013098 (Immunoglobulin I-set), IPR011009 (Protein kinase-like), IPR009134 (Vascular endothelial growth factor receptor, VEGFR, N-terminal), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR000719 (Protein kinase, core), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR013151 (Immunoglobulin)
15	T10B5.8	T10B5.8	n/a	chrV 1,843,425	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
16	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
17	srx-111	T24E12.4	n/a	chrII 3,758,519	C. elegans SRX-111 protein ;
18	C53B4.6	C53B4.6	n/a	chrIV 8,985,786	contains similarity to Pfam domain PF08449 UAA transporter family contains similarity to Interpro domain IPR013657 (UAA transporter)
19	acr-9	C40C9.2	n/a	chrX 13,644,544	acr-9 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors.
20	fbxb-111	F08D12.11	n/a	chrII 2,774,479	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
21	srt-73	T06C10.2	n/a	chrIV 7,880,158	C. elegans SRT-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	T08A9.4	T08A9.4	n/a	chrX 7,313,654	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
23	srt-56	Y73C8C.9	n/a	chrV 3,121,061	C. elegans SRT-56 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
24	ZC53.1	ZC53.1	n/a	chrX 1,912,323
25	srg-22	Y25C1A.10	n/a	chrII 3,092,472	C. elegans SRG-22 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
26	T14E8.2	T14E8.2	n/a	chrX 6,542,867	contains similarity to Interpro domain IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
27	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
28	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
29	srg-16	F15A4.4	n/a	chrII 12,468,465	C. elegans SRG-16 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
30	C07B5.6	C07B5.6	n/a	chrX 9,520,189	contains similarity to Helicobacter pylori Hypothetical protein HP1327.; TR:O25885
31	H14E04.4	H14E04.4	n/a	chrIII 2,391,147
32	sra-24	T06G6.2	n/a	chrI 12,706,029	C. elegans SRA-24 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
33	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
34	B0244.5	B0244.5	n/a	chrIII 5,745,987
35	F26D2.15	F26D2.15	n/a	chrV 16,438,363	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
36	K04E7.1	K04E7.1	n/a	chrX 6,462,585
37	twk-44	Y71H9A.1	n/a	chrX 11,625,639	C. elegans TWK-44 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR011001 (Saposin-like), IPR008139 (Saposin B), IPR013099 (Ion transport 2)
38	R09A8.2	R09A8.2	n/a	chrX 12,621,311	contains similarity to Staphylococcus aureus Serine-rich adhesin for platelets precursor (Staphylococcus aureusssurface protein A).; SW:Q8NUJ3
39	F10A3.7	F10A3.7	n/a	chrV 16,156,140	contains similarity to Pfam domain PF01461 (7TM chemoreceptor)
40	mls-1	H14A12.4	n/a	chrIII 7,461,052	mls-1 encodes a T-box transcription factor orthologous to members of the Tbx1 subfamily of T-box transcription factors (OMIM:602054, mutations in human TBX1 are associated with the developmental disorder DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS)); MLS-1 is required for fate specification of the eight nonstriated uterine muscle cells generated during postembryonic development, and ectopic expression of MLS-1 is sufficient for uterine muscle specification in other mesodermal lineages; mls-1 reporter gene expression is detected in uterine progenitors and differentiated uterine muscles, Type 2 vulval muscles, the left and right intestinal muscles, and the anal depressor muscle; mls-1 expression is positively regulated by the basic helix-loop-helix transcription factors HLH-8/Twist and HLH-2/Daughterless.
41	tax-2	F36F2.5	n/a	chrI 9,023,241	tax-2 is orthologous to the human gene ROD PHOTORECEPTOR CNG-CHANNEL BETA SUBUNIT (CNGB1; OMIM:600724), which when mutated leads to disease.
42	C28A5.5	C28A5.5	n/a	chrIII 4,451,510	contains similarity to Petunia hybrida PGPS/D8.; TR:Q9ZTN1
43	srj-10	F14H3.1	n/a	chrV 16,073,333	C. elegans SRJ-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	vab-15	R07B1.1	n/a	chrX 9,848,439	The vab-15 gene encodes a msh-like homeobox gene that appears required for production of touch cell precursors, and that is orthologous to the human gene MSH HOMEO BOX HOMOLOG 1 (MSX1; OMIM:142983) which when mutated leads to disease.
45	C24H10.1	C24H10.1	n/a	chrX 5,073,103	C24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
46	F02D10.6	F02D10.6	n/a	chrX 13,450,586	contains similarity to Cryptophlebia leucotreta granulosis virus Hypothetical protein.; TR:Q7T5R9
47	srw-55	T05G11.6	n/a	chrV 15,939,538	C. elegans SRW-55 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
48	str-116	F07B10.2	n/a	chrV 11,267,629	C. elegans STR-116 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	pqn-62	T03G11.1	n/a	chrX 5,200,980	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
50	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)