UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T08G11.2	T08G11.2	4e-167	chrI 8,919,920	T08G11.2 encodes a nematode-specific sperm protein, required for a normally high ovulation rate, that interacts with EGL-32; despite not being EGL-32, and although T08G11.2(tm336) complements egl-32(n155), T08G11.2 can partially rescue egl-32 mutants when expressed transgenically, implying that T08G11.2 can be a nonorthologous replacement for EGL-32 function in vivo; T08G11.2 has an SH2 motif, but this motif lacks a critical arginine residue; T08G11.2 has no obvious non-nematode homologs, but is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, and Y81G3A.1); T08G11.2(tm336) hermaphrodites have a lowered ovulation rate (and thus a lowered rate of egg-laying), retaining significantly fewer eggs than wild-type, yet also retaining late-stage embryos; T08G11.2 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs; T08G11.2 expression is strongly enriched in spermatogenesis.
2	R05D3.3	R05D3.3	n/a	chrIII 8,365,486
3	ZC376.8	ZC376.8	n/a	chrV 14,180,879	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR015425 (Actin-binding FH2), IPR004296 (Protein of unknown function DUF236), IPR000694 (Proline-rich region)
4	Y43F8C.5	Y43F8C.5	n/a	chrV 19,631,978	contains similarity to Dictyostelium discoideum Myb-like protein (Fragment).; SW:MYBH_DICDI
5	ZK666.2	ZK666.2	n/a	chrII 10,471,714	contains similarity to Homo sapiens ASH1; ENSEMBL:ENSP00000265206
6	nhr-222	T24A6.11	n/a	chrV 3,542,513	C. elegans NHR-222 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	srd-23	Y40H7A.5	n/a	chrIV 15,181,398	C. elegans SRD-23 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	C35A11.2	C35A11.2	n/a	chrV 5,387,617
9	ttr-6	T28B4.3	n/a	chrX 6,596,773	C. elegans TTR-6 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
10	T08B6.5	T08B6.5	n/a	chrIV 4,890,263	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
11	Y51A2D.1	Y51A2D.1	n/a	chrV 18,510,717	contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	F54F12.1	F54F12.1	n/a	chrIII 13,051,731	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
13	F47F6.4	F47F6.4	n/a	chrII 1,262,570
14	ZK1290.7	ZK1290.7	n/a	chrII 7,524,953	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
15	K09D9.11	K09D9.11	n/a	chrV 3,999,279	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
16	W03G9.5	W03G9.5	n/a	chrI 4,969,127	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
17	K10D6.3	K10D6.3	n/a	chrV 11,201,218	contains similarity to Homo sapiens HMG-BOX transcription factor BBX; ENSEMBL:ENSP00000319742
18	C23H4.6	C23H4.6	n/a	chrX 12,238,124	contains similarity to Pfam domain PF02463 RecF/RecN/SMC N terminal domain contains similarity to Interpro domain IPR003395 (RecF/RecN/SMC protein, N-terminal)
19	Y51A2B.4	Y51A2B.4	n/a	chrV 18,387,652	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
20	ins-39	F21E9.4	n/a	chrX 1,344,119	ins-39 encodes an insulin-like peptide.
21	ZK218.11	ZK218.11	n/a	chrV 17,107,962	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
22	M01A8.1	M01A8.1	n/a	chrIII 9,259,292	contains similarity to Homo sapiens Hypothetical protein KIAA0544; ENSEMBL:ENSP00000262370
23	clec-216	F26D11.5	n/a	chrV 7,952,270	C. elegans CLEC-216 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
24	C06C6.7	C06C6.7	n/a	chrV 15,993,879	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
25	B0207.1	B0207.1	n/a	chrI 5,966,138	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000005 (Helix-turn-helix, AraC type), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
26	F07E5.8	F07E5.8	n/a	chrII 2,074,096	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
27	cyp-29A4	B0331.1	n/a	chrV 9,656,299	C. elegans CYP-29A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR002397 (Cytochrome P450, B-class), IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
28	rab-8	D1037.4	n/a	chrI 3,683,497	rab-8 encodes a rab related protein of the Ras GTPase superfamily that affects ovarian morphology and function, thereby affecting fertility; acts downstream of let-60 with respect to vulval development based on genetic analysis.
29	R05G6.1	R05G6.1	n/a	chrIV 7,539,920
30	twk-37	C48E7.9	n/a	chrI 6,270,306	C. elegans TWK-37 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2)
31	F45C12.9	F45C12.9	n/a	chrII 1,709,067	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
32	C33F10.8	C33F10.8	n/a	chrII 4,824,276	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
33	tub-1	F10B5.4	n/a	chrII 8,155,446	tub-1 encodes a tubby homolog that affects fat storage in C. elegans and may function in a parallel pathway with kat-1 to affect lipid accumulation based on genetic analysis; expressed primarily in sensory neurons.
34	F18C5.4	F18C5.4	n/a	chrII 6,564,443	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001478 (PDZ/DHR/GLGF)
35	M03E7.3	M03E7.3	n/a	chrV 5,615,596
36	cyp-33B1	C25E10.2	n/a	chrV 9,042,479	C. elegans CYP-33B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I)
37	dsl-5	F58B3.8	n/a	chrIV 11,620,190	dsl-5 encodes a putative secreted protein with single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-5 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
38	sulp-2	F14D12.5	n/a	chrX 5,597,522	sulp-2 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-2 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-2 does exhibit modest uptake of sulfate; a SULP-2::GFP fusion is expressed in the intestine and rectal gland cells, where it localizes to the basolateral membrane and in cephalic and deirid neurons, where it localizes to sensillar endings.
39	acy-3	C44F1.5	n/a	chrIII 3,778,374	acy-3 encodes a predicted member of the adenylyl cyclase family with highest similarity to human adenylate cyclase type 5; expressed in the support cells of ciliated neurons, in the head and tail ganglia, in two pairs of neurons in the retrovesicular ganglia, and in the spermatheca.
40	C36E8.4	C36E8.4	n/a	chrIII 4,014,026	contains similarity to Pfam domain PF00018 SH3 domain contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR001452 (Src homology-3)
41	Y116A8A.4	Y116A8A.4	n/a	chrIV 16,823,640	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
42	Y48E1C.3	Y48E1C.3	n/a	chrII 13,439,410	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
43	F10C1.3	F10C1.3	n/a	chrII 5,757,653
44	ZC8.6	ZC8.6	n/a	chrX 4,985,068	contains similarity to Pfam domain PF00454 Phosphatidylinositol 3- and 4-kinase contains similarity to Interpro domain IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic)
45	ZK1086.3	ZK1086.3	n/a	chrX 13,791,278	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
46	Y62H9A.13	Y62H9A.13	n/a	chrX 11,918,504	contains similarity to Homo sapiens Hu-Claspin; ENSEMBL:ENSP00000251195
47	srp-8	F20D6.3	n/a	chrV 8,184,913	srp-8 encodes a predicted serpin (serine protease inhibitor)
48	F46A9.2	F46A9.2	n/a	chrI 9,459,902	contains similarity to Saccharomyces cerevisiae part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); similar to microtubule binding proteins and to X90565_5.cds; SGD:YLR197W
49	C07B5.3	C07B5.3	n/a	chrX 9,522,844
50	fbxb-1	T26H2.1	n/a	chrV 19,240,953	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.