UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxa-3	T08E11.7	7e-160	chrII 1,819,483	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
2	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
3	M01F1.7	M01F1.7	n/a	chrIII 3,525,420	M01F1.7 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); M01F1.7 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; while M01F1.7 would be expected to mediate PIP(2) signalling in either neuronal function or cytokinesis, it has not yet had a published mutant phenotype, and has no obvious function in mass RNAi assays.
4	W01C9.2	W01C9.2	n/a	chrII 8,537,366	contains similarity to Chlamydia pneumoniae Probable serine/threonine-protein kinase 1 (EC 2.7.1.37).; SW:PKN1_CHLPN
5	gpa-3	E02C12.5	n/a	chrV 9,358,223	gpa-3 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects dauer formation, water-soluble chemoattraction and chemoaversion, and volatile chemoattraction; it is expressed in amphid and phasmid neurons and some interneurons.
6	F42A9.9	F42A9.9	n/a	chrIV 8,638,434
7	C25E10.11	C25E10.11	n/a	chrV 9,057,966
8	ins-35	K02E2.4	n/a	chrV 20,371,307	ins-35 encodes one of several insulin-related peptides.
9	T03G11.3	T03G11.3	n/a	chrX 5,175,968	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
10	fbxa-10	T12B5.3	9.999999999999999e-43	chrIII 953,160	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
11	snb-1	T10H9.4	n/a	chrV 6,656,014	The snb-1 gene encodes synaptobrevin, a synaptic vesicle protein orthologous to human vesicle-associated membrane protein 1 (VAMP1 OMIM:185880) and 2 (VAMP2 OMIM:185881), and is required for viability and synaptic transmission; SNB-1 is likely to play a role in vesicle docking and/or fusion and is expressed in neurons where it colocalizes with synaptic vesicle proteins RAB-3 and synaptotagmin.
12	nhr-220	T19H12.8	n/a	chrV 4,883,423	C. elegans NHR-220 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	F56F10.2	F56F10.2	n/a	chrX 861,193	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
14	srx-2	R03H4.2	n/a	chrV 9,010,093	C. elegans SRX-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
15	pgp-10	C54D1.1	n/a	chrX 7,162,476	pgp-10 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-10 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-10 activity via RNAi results in no obvious defects, the exact role of pgp-10 in C. elegans development and/or behavior is not yet known; pgp-10 promoter-gfp fusion proteins are expressed in larvae and adults in the intestine and hypodermis.
16	F15A8.1	F15A8.1	n/a	chrX 4,441,526
17	K09G1.3	K09G1.3	n/a	chrV 9,597,431	contains similarity to Saccharomyces cerevisiae Product of gene unknown; SGD:YKL064W
18	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
19	dhs-16	C10F3.2	n/a	chrV 5,984,592	dhs-16 encodes a short-chain dehydrogenase predicted to be mitochondrial.
20	gly-18	F22D6.11	n/a	chrI 7,111,262	GLY-18 is similar to 2/I N-acetylglucosaminyltransferase.
21	T11F9.14	T11F9.14	n/a	chrV 11,480,742	contains similarity to Oryctolagus cuniculus Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).; SW:TRIF_RABIT
22	clec-37	Y102A5B.3	n/a	chrV 16,851,225	C. elegans CLEC-37 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	R04E5.7	R04E5.7	n/a	chrX 8,797,318
24	T24A6.7	T24A6.7	n/a	chrV 3,525,734	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
25	T23F4.2	T23F4.2	n/a	chrII 1,164,528
26	C01B7.7	C01B7.7	n/a	chrV 8,822,188	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
27	K02F6.8	K02F6.8	n/a	chrII 2,533,862	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
28	Y75B8A.11	Y75B8A.11	n/a	chrIII 12,188,150	contains similarity to Lymnaea stagnalis Neuropeptide Y precursor.; TR:Q9U0S9
29	srw-91	K04F1.4	n/a	chrV 1,680,088	C. elegans SRW-91 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	C38C3.6	C38C3.6	n/a	chrV 1,485,347	contains similarity to Interpro domain IPR000694 (Proline-rich region)
31	pbs-6	C02F5.9	n/a	chrIII 8,243,577	The pbs-6 gene encodes a homolog of mammalian PSMB1.
32	ser-5	F16D3.7	n/a	chrI 8,385,819	F16D3.7 encodes a homolog of mammalian alpha-adrenergic receptors that is expressed in vulval and bodywall muscle cells, intestine, and head neurons; heterologously expressed F16D3.7 has no effect on adenylate cyclase signalling; F16D3.7 has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
33	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
34	K10C8.2	K10C8.2	n/a	chrV 12,691,417	K10C8.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K10C8.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
35	F45F2.6	F45F2.6	n/a	chrV 8,527,305	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
36	K02D3.1	K02D3.1	n/a	chrX 13,707,203	contains similarity to Clostridium acetobutylicum Transcriptional regulator, AcrR family.; TR:Q97IH3
37	clec-243	Y68A4B.1	n/a	chrV 17,248,138	C. elegans CLEC-243 protein; contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
38	ckr-1	T23B3.4	n/a	chrI 6,688,888	T23B3.4 encodes a seven transmembrane receptor that is most closely related to the mammalian cholecystokinin receptors; loss of T23B3.4 activity via RNAi, either singly or in combination with another cholecystokinin receptor-encoding gene, Y39A3B.5, has no effect on fat metabolism, however large-scale RNAi screens have reported that T23B3.4(RNAi) results in embryonic lethality and reduced brood sizes; a T23B3.4::GFP reporter is expressed in a subset of nerve ring neurons.
39	F35C5.11	F35C5.11	n/a	chrII 12,909,598	contains similarity to Mus musculus Lymphocyte antigen Ly-6D precursor (Thymocyte B cell antigen) (ThB).; SW:LY6D_MOUSE
40	B0457.2	B0457.2	n/a	chrII 8,925,501	contains similarity to Homo sapiens Isoform 8 of Elastin precursor; ENSEMBL:ENSP00000369958
41	C39F7.5	C39F7.5	n/a	chrV 1,267,440	contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold)
42	F32B4.5	F32B4.5	n/a	chrI 11,519,244	contains similarity to Homo sapiens BTB/POZ domain-containing protein KCTD16; ENSEMBL:ENSP00000329906
43	glc-3	ZC317.3	n/a	chrV 5,451,485	The glc-3 gene encodes a fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit.
44	T22D1.2	T22D1.2	n/a	chrIV 6,922,337	contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region), IPR000480 (Glutelin), IPR013286 (Annexin, type VII)
45	F41C3.6	F41C3.6	n/a	chrII 4,735,969
46	B0310.3	B0310.3	n/a	chrX 512,692
47	Y38H6C.9	Y38H6C.9	n/a	chrV 20,516,299	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
48	F52D10.6	F52D10.6	n/a	chrX 11,583,279	contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
49	osm-10	T20H4.1	n/a	chrIII 7,244,451	osm-10 encodes a novel protein conserved amongst several Caenorhabditis species; osm-10 activity is required for normal osmosensory signaling in the ASH sensory neuron; in regulating ASH-mediated osmosensation, osm-10 interacts genetically with eos-1 and eos-2; OSM-10 is expressed in the ASH, ASI, PHA, and PHB sensory neurons beginning just prior to hatching and continuing through larval and adult stages; OSM-10 localizes to cell bodies, sensory processes, and axons.
50	tig-2	F39G3.8	n/a	chrV 4,728,435	The tig-2 gene, like dbl-1, daf-7, and unc-129, encodes a TGF-beta-like protein.