UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T08B2.11	T08B2.11	0	chrI 6,222,182	contains similarity to Homo sapiens Transcription initiation factor TFIID subunit 3; ENSEMBL:ENSP00000340271
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	ech-1	C29F3.1	n/a	chrV 15,359,193	ech-1 encodes an enoyl-CoA hydratase; loss of ech-1 activity via RNAi results in reduced body fat, consistent with ECH-1's predicted role in fatty acid metabolism; expression of ech-1 mRNA is positively regulated by the NHR-49 nuclear receptor.
4	C06H2.2	C06H2.2	n/a	chrV 11,126,240	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
5	ZC116.3	ZC116.3	n/a	chrV 12,620,623	ZC116.3 is orthologous to the human gene CUBILIN (CUBN; OMIM:602997), which when mutated leads to hereditary megaloblastic anaemia 1 (OMIM:261100).
6	F55F8.7	F55F8.7	n/a	chrI 5,660,175	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
7	H34I24.2	H34I24.2	n/a	chrIII 2,843,610	contains similarity to Homo sapiens Mucin-7 precursor; ENSEMBL:ENSP00000302021
8	srab-22	T20D4.2	n/a	chrV 3,427,052	C. elegans SRAB-22 protein ;
9	srh-284	C47A10.3	n/a	chrV 17,768,552	C. elegans SRH-284 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	F02C12.1	F02C12.1	n/a	chrX 13,404,175	contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
11	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
12	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
13	lbp-8	T22G5.6	n/a	chrV 13,891,011	lpb-8 belongs to a family of small intracellular fatty acid binding proteins (FABPs) that includes As-p18, found in the parasitic nematode Ascaris suum; lpb-8 shares 55% identity with bovine heart FABP but only 25% identity with As-p18 and lacks a secretory signal
14	C02G6.1	C02G6.1	n/a	chrV 5,878,092	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
15	F01D5.2	F01D5.2	n/a	chrII 13,998,627	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR001368 (TNFR/CD27/30/40/95 cysteine-rich region), IPR000480 (Glutelin), IPR003582 (Metridin-like ShK toxin)
16	F42E8.1	F42E8.1	n/a	chrV 13,063,254	contains similarity to Campylobacter jejuni DNA polymerase III alpha subunit (EC 2.7.7.7).; SW:DP3A_CAMJE
17	clec-67	F56D6.2	n/a	chrIV 3,923,599	C. elegans CLEC-67 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
18	srh-213	T22F3.5	n/a	chrV 3,593,857	C. elegans SRH-213 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	clec-185	C25G4.1	n/a	chrIV 12,440,827	C. elegans CLEC-185 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
20	C03B1.5	C03B1.5	n/a	chrX 6,356,595	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
21	F54D5.14	F54D5.14	n/a	chrII 11,580,652	contains similarity to Pfam domain PF02463 RecF/RecN/SMC N terminal domain contains similarity to Interpro domain IPR003395 (RecF/RecN/SMC protein, N-terminal)
22	abcx-1	C56E6.1	n/a	chrII 6,536,117	C. elegans ABCX-1 protein; contains similarity to Pfam domain PF07539 Down-regulated in metastasis contains similarity to Interpro domains IPR011430 (Down-regulated in metastasis), IPR016024 (Armadillo-type fold)
23	twk-30	F36A2.4	n/a	chrI 8,810,320	C. elegans TWK-30 protein; contains similarity to Pfam domains PF00041 (Fibronectin type III domain) (2), PF07885 (Ion channel) (2)contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR003962 (Fibronectin, type III subdomain), IPR013099 (Ion transport 2)
24	ZC262.5	ZC262.5	n/a	chrIII 8,342,336	contains similarity to Pfam domain PF04627 Mitochondrial ATP synthase epsilon chain contains similarity to Interpro domain IPR006721 (ATPase, F1 complex, epsilon subunit, mitochondrial)
25	pgp-4	F42E11.1	n/a	chrX 11,361,531	pgp-4 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-4 activity via deletion mutations or RNAi results in no obvious defects, the precise role of PGP-4 in C. elegans development and/or behavior is not yet known; pgp-4 promoter-gfp fusion proteins are expressed in the larval excretory cell.
26	F42G2.3	F42G2.3	n/a	chrII 2,420,134
27	F49H6.3	F49H6.3	n/a	chrV 17,015,023	contains similarity to Pfam domain PF06653 Protein of unknown function (DUF1164) contains similarity to Interpro domain IPR009545 (Protein of unknown function DUF1164)
28	T22D1.1	T22D1.1	n/a	chrIV 6,924,455	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR008166 (Protein of unknown function DUF23)
29	math-49	ZK250.7	n/a	chrII 1,954,675	C. elegans MATH-49 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
30	C34H4.2	C34H4.2	n/a	chrIV 1,554,675	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
31	fhod-1	C46H11.11	n/a	chrI 5,063,543	C. elegans FHOD-1 protein; contains similarity to Pfam domain PF02181 Formin Homology 2 Domain contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR014768 (GTPase-binding/formin homology 3), IPR003104 (Actin-binding FH2 and DRF autoregulatory), IPR005398 (Tubby, N-terminal), IPR016024 (Armadillo-type fold)
32	F49F1.8	F49F1.8	n/a	chrIV 4,132,560	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR013084 (Zinc finger, CCHC retroviral-type), IPR001878 (Zinc finger, CCHC-type)
33	nduf-2.2	T26A5.3	n/a	chrIII 6,466,129	T26A5.3 encodes a predicted mitochondrial protein whose mature sequence has near-identity (95%) to GAS-1; T26A5.3 transcription is detectable by RT-PCR, but not visible by promoter-GFP fusion; however, a transgene containing a fusion of the gas-1 promoter to the T26A5.3 protein-coding sequence is able to fully rescue gas-1 mutants, indicating that T26A5.3 encodes a fully functional mitochondrial 49 kDa subunit that may rescue gas-1(fc21) mutants from lethality; mutants homozygous for a T26A5.3 deletion have normal anesthetic sensitivity and normal sensitivity to oxygen (unlike gas-1 mutants) but a shortened lifespan at normal laboratory oxygen levels (20%); animals doubly mutant for gas-1 and T26A5.3 have maternal-effect lethality, but sterile surviving parents are abnormally long-lived (2.7 times longer than wild-type and 4.2 times longer than gas-1 mutants); double mutants remain hypersensitive to oxygen.
34	tag-335	C42C1.5	n/a	chrIV 12,277,039	C. elegans TAG-335 protein; contains similarity to Pfam domains PF00132 (Bacterial transferase hexapeptide (three repeats)) (4), PF00483 (Nucleotidyl transferase) contains similarity to Interpro domains IPR001451 (Bacterial transferase hexapeptide repeat), IPR005835 (Nucleotidyl transferase), IPR011004 (Trimeric LpxA-like)
35	ZK1058.9	ZK1058.9	n/a	chrIII 3,924,612	contains similarity to Borrelia burgdorferi Probable O-sialoglycoprotein endopeptidase (EC 3.4.24.57)s(Glycoprotease).; SW:GCP_BORBU
36	F55A12.6	F55A12.6	n/a	chrI 5,340,452	contains similarity to Interpro domain IPR002952 (Eggshell protein)
37	C13C4.5	C13C4.5	n/a	chrV 12,116,190	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
38	sra-22	F28C12.7	n/a	chrI 12,702,151	C. elegans SRA-22 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR000344 (Nematode chemoreceptor, Sra)
39	spd-5	F56A3.4	n/a	chrI 5,173,414	C. elegans SPD-5 protein; contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
40	fli-1	B0523.5	n/a	chrIII 8,679,606	fli-1 encodes a homolog of Drosophila flightless-I; can interact with human Ha-Ras and human actin in vitro; mRNA levels are highest in embryos.
41	clec-206	F59A7.1	n/a	chrV 2,002,373	C. elegans CLEC-206 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
42	fbf-2	F21H12.5	n/a	chrII 6,090,134	fbf-2 encodes an RNA-binding protein that is one of 11 C. elegans members of the PUF family (Pumilio and FBF) of translational regulators; FBF-2 is nearly identical to FBF-1 with which it is largely redundant in regulating two aspects of germline development: 1)maintenance of stem cell proliferation, and 2)the hermaphroditic switch between spermatogenesis and oogenesis; in maintaining germline stem cells, the FBF proteins, acting through NOS-3, negatively regulate the activity of gld-1 mRNA, which encodes a translational repressor required for meiotic entry; in regulating the sperm-to-oocyte switch, the FBFs act downstream of GLD-3 to negatively regulate the activity of fem-3 mRNA, which encodes a novel protein required for germline sex determination; consistent with their role in germline development, FBF-1 and FBF-2 are expressed in the germline cytoplasm, becoming enriched in the mitotic region during the L4 larval and adult stages.
43	C25H3.4	C25H3.4	n/a	chrII 5,692,793	contains similarity to Pfam domains PF01472 (PUA domain) , PF01253 (Translation initiation factor SUI1) contains similarity to Interpro domains IPR004521 (Uncharacterized domain 2), IPR015947 (PUA-like), IPR001950 (Translation initiation factor SUI1), IPR002478 (PUA)
44	F53B6.5	F53B6.5	n/a	chrI 8,950,742	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR011991 (Winged helix repressor DNA-binding)
45	plc-2	Y75B12B.6	n/a	chrV 15,195,140	C. elegans PLC-2 protein; contains similarity to Pfam domains PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes)
46	E01G4.6	E01G4.6	n/a	chrII 13,483,996	contains similarity to Caenorhabditis remanei P17 (Fragment).; TR:A0MIX2
47	D2089.2	D2089.2	n/a	chrII 10,660,588	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
48	B0454.6	B0454.6	n/a	chrII 3,034,446	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
49	W07E11.1	W07E11.1	n/a	chrX 10,093,967	contains similarity to Pfam domains PF04898 (Glutamate synthase central domain) , PF01645 (Conserved region in glutamate synthase) , PF01266 (FAD dependent oxidoreductase) , PF00310 (Glutamine amidotransferases class-II) , PF07992 (Pyridine nucleotide-disulphide oxidoreductase) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) , PF01493 (GXGXG motif) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000583 (Glutamine amidotransferase, class-II), IPR013785 (Aldolase-type TIM barrel), IPR006076 (FAD dependent oxidoreductase), IPR006005 (Glutamate synthase, NADH/NADPH, small subunit 1), IPR000759 (Adrenodoxin reductase), IPR006982 (Glutamate synthase, central-N), IPR002932 (Glutamate synthase, central-C), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR002489 (Glutamate synthase, alpha subunit, C-terminal), IPR012285 (Fumarate reductase, C-terminal), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR012220 (Glutamate synthase, eukaryotic), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
50	ZK1037.6	ZK1037.6	n/a	chrV 15,326,789	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)