UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-21	T07H3.4	0	chrII 1,583,563	C. elegans CLEC-21 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F22H10.6	F22H10.6	n/a	chrX 16,690,126
4	R105.1	R105.1	n/a	chrIV 4,635,811	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
5	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
6	C25A1.5	C25A1.5	n/a	chrI 10,178,041	contains similarity to Pfam domains PF04116 (Fatty acid hydroxylase superfamily) , PF00173 (Cytochrome b5-like Heme/Steroid binding domain) contains similarity to Interpro domains IPR006694 (Fatty acid hydroxylase), IPR001199 (Cytochrome b5)
7	F52H2.7	F52H2.7	n/a	chrX 2,569,600	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
8	T15D6.4	T15D6.4	n/a	chrI 12,375,417	contains similarity to Aedes aegypti N-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase.; TR:Q175J5
9	Y45G12C.6	Y45G12C.6	n/a	chrV 2,541,544	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	F21C10.5	F21C10.5	n/a	chrV 9,125,800	contains similarity to Xenopus tropicalis H/ACA ribonucleoprotein complex subunit 1-like protein.; SW:Q5RJV1
11	Y41C4A.9	Y41C4A.9	n/a	chrIII 11,714,688	contains similarity to Pfam domain PF06862 Protein of unknown function (DUF1253) contains similarity to Interpro domain IPR010678 (Protein of unknown function DUF1253)
12	C34F6.5	C34F6.5	n/a	chrX 11,208,547	contains similarity to Homo sapiens Histone acetyltransferase MORF beta; ENSEMBL:ENSP00000287239
13	srw-61	H25K10.7	n/a	chrIV 16,237,697	C. elegans SRW-61 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor)
14	C54F6.3	C54F6.3	n/a	chrV 7,534,164	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
15	wts-1	T20F10.1	n/a	chrI 10,294,898	C. elegans WTS-1 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00433 (Protein kinase C terminal domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
16	his-34	F17E9.9	n/a	chrIV 8,336,138	his-34 encodes an H2B histone; his-34 is contained within the histone gene cluster HIS5.
17	K08C7.7	K08C7.7	n/a	chrIV 10,665,006	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
18	scrm-3	C04E12.7	n/a	chrV 3,356,584	scrm-3 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); SCRM-3 is expressed in neurons, anal depressor muscle, and occasionally in body wall muscle cells; however, in apoptotic germline cells, SCRM-3 is fully dispensable for normally rapid engulfment and largely dispensable for phosphatidylserine exposure; SCRM-3 does not bind WAH-1 in vitro, and scrm-3(tm631) mutants have no obvious phenotype.
19	fbxb-39	M01D1.7	n/a	chrII 1,040,136	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
20	tsp-7	T23D8.2	n/a	chrI 9,971,579	C. elegans TSP-7 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
21	C54D2.1	C54D2.1	n/a	chrX 7,843,978	contains similarity to Pfam domain PF01683 EB module contains similarity to Interpro domains IPR006149 (Nematode-specific EB region), IPR002557 (Chitin binding protein, peritrophin-A)
22	ZK550.2	ZK550.2	n/a	chrIV 17,247,626	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
23	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
24	pkc-1	F57F5.5	n/a	chrV 12,019,252	pkc-1 encodes a serine/threonine protein kinase that is orthologous to mammalian protein kinase C epsilon (PRKCE), a member of the nPKC subgroup of the protein kinase C superfamily; together with UNC-13, PKC-1 may act downstream of goa-1 to modulate phorbol ester-induced stimulation of acetylcholine release at NMJs; PKC-1 positively regulates locomotion, and affects thermotaxis and chemotaxis together with kin-11; PKC-1 is required for regulating several behaviors including sensation of volatile and soluble compounds, osmolarity, and temperature (thermosensation); PKC-1 is also required for phorbolester-induced stimulation of acetylcholine release at neuromuscular junctions; PKC-1 localizes to the processes and cell bodies of approximately 75 sensory neurons and interneurons, and pkc-1 mRNA is detectable at varying levels during larval and adult stages.
25	srh-111	F08E10.6	n/a	chrV 17,484,578	C. elegans SRH-111 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	F43C1.1	F43C1.1	n/a	chrIII 4,213,606	contains similarity to Pfam domains PF00481 (Protein phosphatase 2C) , PF00560 (Leucine Rich Repeat) (11)contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR001611 (Leucine-rich repeat), IPR000694 (Proline-rich region), IPR003591 (Leucine-rich repeat, typical subtype), IPR014045 (Protein phosphatase 2C, N-terminal)
27	C50F7.6	C50F7.6	n/a	chrIV 7,721,871	contains similarity to Homo sapiens Isoform 4 of PDZ domain-containing RING finger protein 4; ENSEMBL:ENSP00000370169
28	C53D6.7	C53D6.7	n/a	chrIV 9,035,988	contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
29	F08D12.7	F08D12.7	n/a	chrII 2,768,193	F08D12.7 encodes a novel protein conserved amongst Caenorhaditis species; although loss of F08D12.7 activity via RNAi results in no obvious defects, F08D12.7 transcripts are enriched in L1-stage muscle and upregulated in L2 larvae in response to overexpression of hlh-2 and hlh-8; in addition, in analyses of the early embryonic transcriptome, F08D12.7 transcripts are classified as strictly maternal; an F08D12.7::gfp reporter fusion is expressed in the vm1 and vm2 vulval muscles, the intestinal and anal depressor muscles, the hypodermis, distal tip cell, ventral nerve cord, head and tail neurons, and body wall muscle.
30	K04G11.3	K04G11.3	n/a	chrX 14,346,393	contains similarity to Pfam domain PF07547 RSD-2 N-terminal domain contains similarity to Interpro domain IPR011508 (RSD-2, N-terminal)
31	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
32	F33H12.1	F33H12.1	n/a	chrII 2,601,167	contains similarity to Pfam domain PF00533 BRCA1 C Terminus (BRCT) domain contains similarity to Interpro domain IPR001357 (BRCT)
33	B0244.7	B0244.7	n/a	chrIII 5,732,127	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
34	Y57G11A.3	Y57G11A.3	n/a	chrIV 14,502,754	contains similarity to Pfam domain PF00412 LIM domain contains similarity to Interpro domain IPR001781 (Zinc finger, LIM-type)
35	B0334.6	B0334.6	n/a	chrII 11,512,193	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
36	sri-42	T10D4.9	n/a	chrII 3,141,931	C. elegans SRI-42 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	R06B9.4	R06B9.4	n/a	chrII 13,754,197	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
38	W08D2.5	W08D2.5	n/a	chrIV 9,821,001	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR000150 (Cof protein), IPR005834 (Haloacid dehalogenase-like hydrolase)
39	F22F7.2	F22F7.2	n/a	chrV 2,125,082	contains similarity to Pfam domain PF03435 Saccharopine dehydrogenase contains similarity to Interpro domains IPR005097 (Saccharopine dehydrogenase), IPR016040 (NAD(P)-binding)
40	T05G5.5	T05G5.5	n/a	chrIII 9,750,414	contains similarity to Pfam domain PF01121 Dephospho-CoA kinase contains similarity to Interpro domains IPR000764 (Uridine kinase), IPR001977 (Dephospho-CoA kinase)
41	frm-9	F31B12.3	n/a	chrX 10,817,663	frm-9 encodes a B41/ERM (ezrin/radixin/moesin) domain containing protein.
42	C05A9.3	C05A9.3	n/a	chrX 10,830,625	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
43	hap-1	ZC395.7	n/a	chrIII 5,264,428	C. elegans HAP-1 protein; contains similarity to Pfam domain PF01725 Ham1 family contains similarity to Interpro domain IPR002637 (Ham1-like protein)
44	F49B2.3	F49B2.3	n/a	chrI 14,311,927	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region)
45	gtl-2	F54D1.5	n/a	chrIV 11,277,712	gtl-2 encodes a predicted receptor-activated calcium channel and represents a family of calcium channels, the other two family members being gtl-1 and gon-2.
46	sdz-15	F23F12.4	n/a	chrIII 6,499,273	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
47	his-1	T10C6.14	n/a	chrV 16,042,648	his-1 encodes an H4 histone; his-1 is contained within the histone gene cluster HIS1; transcript analysis suggests that it encodes the major class of H4 transcripts.
48	atp-4	T05H4.12	n/a	chrV 6,426,736	C. elegans ATP-4 protein; contains similarity to Pfam domain PF05511 Mitochondrial ATP synthase coupling factor 6 contains similarity to Interpro domain IPR008387 (ATPase, F0 complex, subunit F6, mitochondrial)
49	sre-49	C50E10.9	n/a	chrII 12,319,870	C. elegans SRE-49 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
50	clec-242	Y68A4B.2	n/a	chrV 17,244,604	C. elegans CLEC-242 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)