UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-214	T07C5.3	0	chrX 12,701,293	C. elegans NHR-214 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	K04B12.3	K04B12.3	n/a	chrII 14,444,229	contains similarity to Anopheles gambiae str PEST AGAP010179-PA (Fragment).; TR:Q7Q0T1
3	gnrr-7	F13D2.3	n/a	chrX 11,186,568	C. elegans GNRR-7 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
4	grl-28	T24A6.15	n/a	chrV 3,551,603	grl-28 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
5	R03A10.5	R03A10.5	n/a	chrX 15,448,432	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR000348 (emp24/gp25L/p24)
6	C14C6.6	C14C6.6	n/a	chrV 546,947	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
7	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
8	clec-147	C04H5.2	n/a	chrII 14,536,651	C. elegans CLEC-147 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
9	F46B3.16	F46B3.16	n/a	chrV 20,630,275
10	bli-3	F56C11.1	n/a	chrI 150,659	bli-3 encodes a large homolog of dual oxidase ('Ce-Duox1'), with an N-terminal peroxidase domain, two central calmodulin-binding EF hands, and a C-terminal superoxide-generating NADPH-oxidase domain; BLI-3 is required for dityrosine cross-linking of collagen, and thus for cuticular integrity; BLI-3 is thought to use cytosolic NADPH to generate reactive oxygen, which then drives the peroxidase ectodomain to cross-link free tyrosine in collagen; BLI-3 is expressed exclusively in hypodermal cells at low levels, with peaks of expression corresponding to collagen/cuticle biosynthesis.
11	E01B7.1	E01B7.1	n/a	chrV 17,926,717	contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR000694 (Proline-rich region)
12	inx-7	K02B2.4	n/a	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
13	B0491.1	B0491.1	n/a	chrII 11,349,105	contains similarity to Pfam domain PF05007 Mannosyltransferase (PIG-M) contains similarity to Interpro domain IPR007704 (Mannosyltransferase, DXD)
14	K10C2.6	K10C2.6	n/a	chrX 6,451,568
15	scrm-2	ZK1053.5	n/a	chrI 13,235,906	scrm-2 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); in apoptotic germline cells, SCRM-2 is fully dispensable for normally rapid engulfment and largely dispensable for phosphatidylserine exposure; SCRM-2 does not bind WAH-1 in vitro, and scrm-2(tm650) mutants have no obvious phenotype.
16	srw-83	ZK262.6	n/a	chrV 18,428,523	C. elegans SRW-83 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
17	K02B2.6	K02B2.6	n/a	chrIV 5,961,963
18	sri-54	T10D4.8	n/a	chrII 3,136,737	C. elegans SRI-54 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001411 (Tetracycline resistance protein, TetB)
19	Y54E2A.4	Y54E2A.4	n/a	chrII 14,754,890	contains similarity to Archaeoglobus fulgidus NADH oxidase (NOXA-3).; TR:O29847
20	M151.2	M151.2	n/a	chrII 3,632,782	contains similarity to Interpro domain IPR000533 (Tropomyosin)
21	F10E7.6	F10E7.6	n/a	chrII 7,113,277
22	twk-4	ZK1067.5	n/a	chrII 9,192,128	C. elegans TWK-4 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
23	fbxb-118	W06A11.3	n/a	chrII 4,063,201	C. elegans FBXB-118 protein ;
24	K06H6.5	K06H6.5	n/a	chrV 577,400	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
25	C08B6.10	C08B6.10	n/a	chrV 10,126,265	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
26	T27A3.7	T27A3.7	n/a	chrI 6,108,746	contains similarity to Pfam domain PF00130 Phorbol esters/diacylglycerol binding domain (C1 domain) contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR001781 (Zinc finger, LIM-type)
27	C54H2.4	C54H2.4	n/a	chrX 5,768,086
28	srh-236	Y68A4A.9	n/a	chrV 17,211,345	C. elegans SRH-236 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	lgc-18	T01H10.7	n/a	chrX 12,126,727	C. elegans LGC-18 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
30	str-181	R11D1.6	n/a	chrV 12,717,648	C. elegans STR-181 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	F14D2.6	F14D2.6	n/a	chrII 3,331,956	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
32	F31F7.3	F31F7.3	n/a	chrV 6,269,506
33	W03H9.1	W03H9.1	n/a	chrII 14,148,639	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
34	Y75B8A.28	Y75B8A.28	n/a	chrIII 12,320,885	contains similarity to Saccharomyces cerevisiae Required for START A of cell cycle, and glucose and nitrogen repression of sporulation; SGD:YJL005W
35	F11G11.13	F11G11.13	n/a	chrII 4,875,478	contains similarity to Pfam domain PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain contains similarity to Interpro domains IPR000749 (ATP:guanido phosphotransferase), IPR014746 (Glutamine synthetase/guanido kinase, catalytic region)
36	fbxa-165	C08E3.8	n/a	chrII 1,615,632	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
37	B0336.3	B0336.3	n/a	chrIII 5,713,118	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domains IPR000571 (Zinc finger, CCCH-type), IPR000694 (Proline-rich region), IPR000504 (RNA recognition motif, RNP-1), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR001984 (Peptidase S16, Lon protease)
38	gld-1	T23G11.3	n/a	chrI 7,696,949	gld-1 encodes a protein containing a K homology RNA binding domain that is required for meiotic cell cycle progression during oogenesis in parallel with gld-2, and also affects spermatogenesis; it physically interacts with its putative mRNA targets in vitro and with FOG-2, and is expressed in the cytoplasm at high levels during meiotic prophase.
39	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
40	K04F1.13	K04F1.13	n/a	chrV 1,652,895	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
41	srxa-10	R10E11.7	n/a	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
42	F36H12.17	F36H12.17	n/a	chrIV 5,277,187
43	nhr-89	E03H4.13	n/a	chrI 12,440,583	C. elegans NHR-89 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	bra-1	F54B11.6	n/a	chrX 13,598,994	The bra-1 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1) that negatively regulates the DAF-1/DAF-7/DAF-14 TGF-beta signalling pathway.
45	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
46	T07D3.2	T07D3.2	n/a	chrII 902,779	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
47	T10E9.5	T10E9.5	n/a	chrI 6,522,462
48	clec-102	F33E2.3	n/a	chrI 12,579,521	C. elegans CLEC-102 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
49	nhr-76	C05G6.1	n/a	chrIV 630,739	C. elegans NHR-76 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
50	F18A12.5	F18A12.5	n/a	chrII 3,397,557	F18A12.5 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.5 has no clear orthologs in other organisms.