UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ttr-15	T07C4.5	2e-70	chrIII 10,338,481	C. elegans TTR-15 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
4	F56B6.6	F56B6.6	n/a	chrX 3,532,316	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
5	T20D4.7	T20D4.7	n/a	chrV 3,409,192	contains similarity to Pfam domains PF08534 (Redoxin) , PF00578 (AhpC/TSA family) contains similarity to Interpro domains IPR011594 (Thioredoxin-like), IPR013740 (Redoxin), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000866 (Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen), IPR006662 (Thioredoxin-related)
6	F26G1.3	F26G1.3	n/a	chrII 4,759,013	F26G1.3 encodes a protein containing a transthyretin-like domain; the product of F26G1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
7	ZK669.3	ZK669.3	n/a	chrII 7,941,811	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
8	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
9	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
10	ttr-30	T08A9.2	0.0000002	chrX 7,331,455	C. elegans TTR-30 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
11	ttr-32	R13A5.3	0.000000002	chrIII 7,566,923	R13A5.3 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although the product of R13A5.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of R13A5.3 activity via RNAi has been reported to result in hyperactive locomotion.
12	Y37D8A.21	Y37D8A.21	n/a	chrIII 12,929,839	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
13	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.
14	srp-2	C05E4.1	n/a	chrV 763,702	srp-2 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily that is orthologous to human NEUROSERPIN (OMIM:602445, mutated in familial encephalopathy with neuroserpin inclusion bodies); SRP-2 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases, and in vitro, recombinant SRP-2 is able to inhibit granzyme B activity; however, as loss of srp-2 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-2 in C. elegans development and/or behavior is not yet known; srp-2 expression is detected in hypodermal cells, particularly in the lateral seam cells.
15	Y57G11C.18	Y57G11C.18	n/a	chrIV 14,841,760	contains similarity to Interpro domain IPR000767 (Disease resistance protein)
16	K08D8.1	K08D8.1	n/a	chrIV 12,893,458	contains similarity to Fusobacterium nucleatum Tryptophanase (EC 4.1.99.1).; TR:Q8RHQ6
17	scl-27	ZK6.3	n/a	chrV 400,930	C. elegans SCL-27 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
18	C50B6.1	C50B6.1	n/a	chrV 13,308,835	contains similarity to Synechocystis sp Hypothetical protein slr1813.; TR:P73698
19	D2007.1	D2007.1	n/a	chrIII 8,155,633
20	btb-7	F45C12.12	n/a	chrII 1,713,745	C. elegans BTB-7 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
21	inx-9	ZK792.3	n/a	chrIV 11,677,349	inx-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; although the precise role of INX-9 in C. elegans development and/or behavior is not yet known, INX-9 may play a role in gonad or germline development, as INX-9 expression is detected solely in the sheath cells of the somatic gonad and particularly, the sheath cells in contact with proximal oocytes.
22	C42C1.2	C42C1.2	n/a	chrIV 12,266,886	contains similarity to Pfam domain PF00481 Protein phosphatase 2C contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR000222 (), IPR014045 (Protein phosphatase 2C, N-terminal), IPR015655 (Protein phosphatase 2C)
23	C10H11.8	C10H11.8	n/a	chrI 4,736,771	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
24	sms-2	F53H8.4	n/a	chrX 946,855	C. elegans SMS-2 protein ; contains similarity to Aedes aegypti Spingomyelin synthetase.; TR:Q17C34
25	F52E10.4	F52E10.4	n/a	chrX 16,286,357	contains similarity to Homo sapiens Zinc finger protein 277; ENSEMBL:ENSP00000006035
26	grd-3	W05E7.1	n/a	chrIV 3,440,050	grd-3 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; GRD-3 is expressed in adult anterior and posterior seam cells, overlapping GRD-5 expression; GRD-3 is also strongly expressed upon infection with the gram-negative bacterium Serratia marcescens, indicating that GRD-3 may be part of C. elegans' innate immunity response; the Ground domain is predicted to form a cysteine-crosslinked protein acting as an intercellular signal, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-3 is weakly required for normal molting; GRD-3 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
27	ttr-37	F21E9.3	0.000003	chrX 1,336,135	C. elegans TTR-37 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
28	C24F3.2	C24F3.2	n/a	chrIV 10,223,062	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016278 (Tyrosine protein phosphatase, dual specificity, 12), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
29	R148.4	R148.4	n/a	chrIII 3,172,188
30	C50B8.1	C50B8.1	n/a	chrV 13,566,397	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
31	C47D12.5	C47D12.5	n/a	chrII 11,685,843
32	srg-23	Y25C1A.11	n/a	chrII 3,095,026	C. elegans SRG-23 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
33	F14H3.12	F14H3.12	n/a	chrV 16,074,705	contains similarity to Pfam domain PF02149 Kinase associated domain 1 contains similarity to Interpro domain IPR001772 (Kinase-associated KA1)
34	C03B1.2	C03B1.2	n/a	chrX 6,370,343
35	R03H4.5	R03H4.5	n/a	chrV 9,020,799	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
36	cyp-32A1	C26F1.2	n/a	chrV 7,783,180	C. elegans CYP-32A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
37	C25E10.10	C25E10.10	n/a	chrV 9,055,890	C25E10.10 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C25E10.10 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C25E10.10 has no obvious function in mass RNAi assays.
38	Y106G6D.6	Y106G6D.6	n/a	chrI 10,120,080	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
39	W03G9.2	W03G9.2	n/a	chrI 4,963,346	contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR001545 (Gonadotropin, beta chain)
40	C17E4.4	C17E4.4	n/a	chrI 9,419,701	contains similarity to Thermoplasma acidophilum Hypothetical membrane protein.; TR:Q9HLF7
41	M02B7.1	M02B7.1	n/a	chrIV 3,806,054
42	K07C11.3	K07C11.3	n/a	chrV 8,207,597	contains similarity to Interpro domains IPR008993 (TIMP-like, OB-fold), IPR001820 (Proteinase inhibitor I35, tissue inhibitor of metalloproteinase), IPR001134 (Netrin, C-terminal)
43	C49H3.12	C49H3.12	n/a	chrIV 7,927,035
44	Y40H7A.11	Y40H7A.11	n/a	chrIV 15,219,977	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
45	T04A11.5	T04A11.5	n/a	chrIV 12,485,693	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
46	F35E8.7	F35E8.7	n/a	chrV 15,914,552	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR003582 (Metridin-like ShK toxin)
47	T04A11.1	T04A11.1	n/a	chrIV 12,476,146	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
48	col-51	T28F2.8	n/a	chrI 3,654,613	col-51 encodes a cuticle collagen.
49	Y40H7A.9	Y40H7A.9	n/a	chrIV 15,207,561	contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
50	C33A12.7	C33A12.7	n/a	chrIV 9,507,832	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)