UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sra-24	T06G6.2	0	chrI 12,706,029	C. elegans SRA-24 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
4	F59B1.4	F59B1.4	n/a	chrV 3,626,020	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000194 (ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)
5	C53B4.6	C53B4.6	n/a	chrIV 8,985,786	contains similarity to Pfam domain PF08449 UAA transporter family contains similarity to Interpro domain IPR013657 (UAA transporter)
6	clec-227	F08H9.5	n/a	chrV 14,473,432	C. elegans CLEC-227 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
7	dbl-1	T25F10.2	n/a	chrV 6,759,095	dbl-1 encodes a member of the transforming growth factor beta (TGFbeta) superfamily that includes Drosophila decapentaplegic (Dpp) and the vertebrate bone morphogenetic proteins (BMPs); DBL-1 functions as a dose-dependent ligand for the SMA-6 and DAF-4 TGFbeta receptors that ultimately activate the SMA-2, -3, and -4 complex of transcription factors to regulate body length and size, as well as the patterning of male sensory rays and copulatory spicules; DBL-1 signaling upregulates sma-6 expression, suggesting that there is positive autoregulation in the DBL-1 signaling pathway; in contrast, DBL-1 negatively regulates expression of LON-1, a predicted secreted protein that is a downstream component of the body size pathway; DBL-1 is expressed primarily in neurons.
8	clec-143	ZK673.9	n/a	chrII 10,469,224	C. elegans CLEC-143 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR000158 (Cell division protein FtsZ, N-terminal), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
9	Y57G7A.6	Y57G7A.6	n/a	chrII 1,283,801	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
10	B0244.5	B0244.5	n/a	chrIII 5,745,987
11	D1014.2	D1014.2	n/a	chrV 8,145,287	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
12	fbxa-89	Y75B8A.21	n/a	chrIII 12,237,580	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
13	ZK380.4	ZK380.4	n/a	chrX 1,652,654
14	K04E7.1	K04E7.1	n/a	chrX 6,462,585
15	F56H6.3	F56H6.3	n/a	chrI 12,289,861
16	F14F9.3	F14F9.3	n/a	chrV 5,139,826	contains similarity to Interpro domain IPR002867 (Zinc finger, C6HC-type)
17	T10E10.3	T10E10.3	n/a	chrX 6,313,109	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
18	R13.2	R13.2	n/a	chrIV 10,826,996	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
19	pqn-62	T03G11.1	n/a	chrX 5,200,980	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
20	srj-10	F14H3.1	n/a	chrV 16,073,333	C. elegans SRJ-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	sre-56	C50E10.8	n/a	chrII 12,326,444	C. elegans SRE-56 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR002090 (Na+/H+ exchanger, isoform 6 (NHE6)), IPR000276 (GPCR, rhodopsin-like)
23	acr-9	C40C9.2	n/a	chrX 13,644,544	acr-9 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors.
24	srt-56	Y73C8C.9	n/a	chrV 3,121,061	C. elegans SRT-56 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
25	T08G5.1	T08G5.1	n/a	chrV 14,019,744	contains similarity to Saccharomyces cerevisiae Protein that may function as a cochaperone, as suggested by the presence of a DnaJ-like domain; SGD:YNL227C
26	ZC266.1	ZC266.1	n/a	chrV 4,700,209
27	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
28	srg-2	C18F10.5	n/a	chrIII 6,259,346	srg-2 encodes a predicted seven transmembrane domain G protein-coupled chemosensory receptor; an SRG-2::GFP fusion protein is expressed exclusively in the cilia of ASK sensory neurons, which are believed to be involved in chemotaxis to lysine and sensory regulation of egg laying; localization of SRG-2 to ASK cilia does not appear to depend upon wild-type activity of either odr-4 or odr-8.
29	srx-7	C14C6.1	n/a	chrV 561,828	C. elegans SRX-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
30	F38E1.11	F38E1.11	n/a	chrV 8,379,393
31	W09G12.8	W09G12.8	n/a	chrIV 1,226,925	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
32	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
33	F08D12.4	F08D12.4	n/a	chrII 2,778,750	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
34	vab-15	R07B1.1	n/a	chrX 9,848,439	The vab-15 gene encodes a msh-like homeobox gene that appears required for production of touch cell precursors, and that is orthologous to the human gene MSH HOMEO BOX HOMOLOG 1 (MSX1; OMIM:142983) which when mutated leads to disease.
35	W09C5.1	W09C5.1	n/a	chrI 13,627,524	contains similarity to Pfam domain PF01201 Ribosomal protein S8e contains similarity to Interpro domain IPR001047 (Ribosomal protein S8e)
36	C14A11.6	C14A11.6	n/a	chrX 2,812,319
37	C34D4.10	C34D4.10	n/a	chrIV 7,120,692
38	F54B11.8	F54B11.8	n/a	chrX 13,602,980	contains similarity to Silene gallica Reverse transcriptase (Fragment).; TR:Q8W3T3
39	T22E5.3	T22E5.3	n/a	chrX 6,386,631	contains similarity to Pfam domains PF01682 (DB module) , PF00041 (Fibronectin type III domain) contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR002602 (Protein of unknown function DB), IPR007110 (Immunoglobulin-like)
40	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	srg-16	F15A4.4	n/a	chrII 12,468,465	C. elegans SRG-16 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
42	ZK721.3	ZK721.3	n/a	chrX 8,785,606
43	C28A5.5	C28A5.5	n/a	chrIII 4,451,510	contains similarity to Petunia hybrida PGPS/D8.; TR:Q9ZTN1
44	C40H1.3	C40H1.3	n/a	chrIII 9,328,239	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000003630
45	C24H10.1	C24H10.1	n/a	chrX 5,073,103	C24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
46	srt-73	T06C10.2	n/a	chrIV 7,880,158	C. elegans SRT-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	F21G4.4	F21G4.4	n/a	chrX 9,898,328	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
48	srg-9	T12A2.10	n/a	chrIII 6,256,061	C. elegans SRG-9 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
49	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
50	F54C1.1	F54C1.1	n/a	chrI 5,011,081	contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)