UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-213	T06C12.13	0	chrV 15,895,604	C. elegans NHR-213 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	aat-1	F27C8.1	n/a	chrIV 9,600,317	aat-1 encodes an amino acid transporter catalytic subunit; when co-expressed in Xenopus oocytes with the ATG-2 glycoprotein subunit, AAT-1 is able to facilitate amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; in addition, AAT-1 is able to covalently associate with ATG-2 or ATG-1 to form heterodimers in the Xenopus expression system; when co-expressed with ATG-2, AAT-1 localizes to the cell surface of oocytes, but when expressed alone or with ATG-1, AAT-1 localizes intracellularly.
4	chd-3	T14G8.1	n/a	chrX 12,849,438	chd-3 encodes a PHD-finger SNF2 family member containing a chromo domain and a C-terminal helicase domain that affects Notch-dependent vulval development; expressed in virtually all embryonic cells and in many larval nuclei.
5	str-148	M01D1.1	n/a	chrII 1,047,396	C. elegans STR-148 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
6	F27B3.6	F27B3.6	n/a	chrIII 6,578,178
7	srg-67	ZC317.4	n/a	chrV 5,462,245	C. elegans SRG-67 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
8	ceh-34	C10G8.6	n/a	chrV 5,317,530	ceh-34 encodes a homeodomain protein, homologous to human SIX2 (OMIM:604994), that is expressed very weakly in the pharynxes of late embryos and early larvae; it has no known function.
9	K02E7.11	K02E7.11	n/a	chrII 1,075,134
10	R12B2.6	R12B2.6	n/a	chrIII 5,834,841
11	F14H8.5	F14H8.5	n/a	chrV 15,021,516	contains similarity to Bacillus cereus Hypothetical membrane spanning protein.; TR:Q812W2
12	fbxa-220	Y66A7A.1	n/a	chrIII 11,483,373	C. elegans FBXA-220 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
13	Y41C4A.13	Y41C4A.13	n/a	chrIII 11,735,378	contains similarity to Homo sapiens Rabconnectin; ENSEMBL:ENSP00000251076
14	fpn-1.3	R08F11.6	n/a	chrV 3,796,213	C. elegans FPN-1.3 protein; contains similarity to Pfam domain PF06963 Ferroportin1 (FPN1) contains similarity to Interpro domains IPR009716 (Ferroportin1), IPR016196 (MFS general substrate transporter)
15	Y53C10A.3	Y53C10A.3	n/a	chrI 11,969,389	Y53C10A.3 encodes a paralog of HSF-1 that might regulate ubq-1, since ubq-1 has 5'-flanking sequences resembling heat shock regulatory elements, yet is uninduced by heat shock.
16	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
17	clpp-1	ZK970.2	n/a	chrII 10,301,745	clpp-1 encodes a mitochondrial protein, homologous to bacterial ClpP, required to initiate the stress response to unfolded mitochondrial proteins; as with its bacterial ortholog, CLPP-1 is predicted to be a proteolytic subunit of a Clp-like protease, with an N-terminal region required for mitochondrial localization, and a C-terminal region of ClpP similarity; in response to a mutation stressing mitochondria, clpp-1(RNAi) animals show reduced HSP-60 levels, inhibited nuclear translocation and hsp-60 activation by DVE-1, and aberrant mitochondrial morphology; CLPP-1 is biochemically inhibited by the ClpP inhibitor Z-LY-CMK and the peptide aldehyde MG132, and may also be blocked by them when injected in vivo; CLPP-1 is expressed in the intestine.
18	T21E12.2	T21E12.2	n/a	chrI 4,414,499	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
19	ZK430.5	ZK430.5	n/a	chrII 4,411,199	contains similarity to Pfam domain PF03568 Peptidase family C50 contains similarity to Interpro domain IPR005314 (Peptidase C50, separase)
20	C12D5.10	C12D5.10	n/a	chrV 7,692,770	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
21	srw-138	C44C3.3	n/a	chrV 2,962,370	C. elegans SRW-138 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
22	C40A11.4	C40A11.4	n/a	chrII 2,138,139	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
23	fbxb-85	R17.1	n/a	chrIII 10,848,088	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
24	EEED8.12	EEED8.12	n/a	chrII 5,408,624	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
25	B0041.3	B0041.3	n/a	chrI 4,645,153	contains similarity to Pfam domain PF01476 LysM domain contains similarity to Interpro domain IPR002482 (Peptidoglycan-binding LysM)
26	C08H9.1	C08H9.1	n/a	chrII 9,876,448	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
27	skr-19	R12H7.3	n/a	chrX 13,224,084	The skr-19 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-19(RNAi) animals are at least superficially normal.
28	F15G9.5	F15G9.5	n/a	chrX 9,735,456	contains similarity to Homo sapiens Fibrillin 2 precursor; ENSEMBL:ENSP00000262464
29	F22F1.3	F22F1.3	n/a	chrX 8,162,399	contains similarity to Pfam domain PF02172 KIX domain contains similarity to Interpro domain IPR003101 (Coactivator CBP, KIX)
30	C46H3.3	C46H3.3	n/a	chrX 1,228,487	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
31	LLC1.2	LLC1.2	n/a	chrIV 14,460,481	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
32	C08H9.6	C08H9.6	n/a	chrII 9,873,847	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
33	srbc-6	C36C5.3	n/a	chrV 3,170,772	C. elegans SRBC-6 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
34	R08B4.3	R08B4.3	n/a	chrX 11,119,911	contains similarity to Homo sapiens 23 kDa protein; VG:OTTHUMP00000170038
35	srg-37	K04C1.1	n/a	chrX 14,234,536	C. elegans SRG-37 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
36	C29F9.1	C29F9.1	n/a	chrIII 133,396
37	srt-29	C24B9.5	n/a	chrV 2,718,264	C. elegans SRT-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR001991 (Sodium:dicarboxylate symporter)
38	F27E11.1	F27E11.1	n/a	chrV 3,464,980	contains similarity to Pfam domains PF01773 (Na+ dependent nucleoside transporter N-terminus) , PF07670 (Nucleoside recognition) , PF07662 (Na+ dependent nucleoside transporter C-terminus) contains similarity to Interpro domains IPR008276 (Concentrative nucleoside transporter), IPR002668 (Na+ dependent nucleoside transporter), IPR011657 (Na+ dependent nucleoside transporter, C-terminal), IPR011642 (Nucleoside recognition)
39	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	Y17D7C.2	Y17D7C.2	n/a	chrV 18,717,931	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
41	C32B5.5	C32B5.5	n/a	chrII 974,906	contains similarity to Pfam domain PF00646 F-box domain
42	F53A3.1	F53A3.1	n/a	chrIII 1,941,574
43	arl-6	C38D4.8	n/a	chrIII 4,814,024	arl-6 encodes an ADP-Ribosylation factor-Like member of the Ras superfamily of small GTP-binding proteins and is a predicted homolog of the human ARL6 gene, identified as the gene that underlies Bardet-Biedl syndrome type 3; GFP-tagged ARL-6 undergoes intraflagellar transport (IFT) in the ciliary axoneme, implicating ARL-6 in ciliary transport; arl-6 is expressed in amphid and phasmid ciliated sensory neurons.
44	W04B5.6	W04B5.6	n/a	chrIII 2,434,376
45	T20F7.5	T20F7.5	n/a	chrX 16,850,352	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	F01G10.7	F01G10.7	n/a	chrIV 10,240,539	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
47	ace-4	Y48B6A.7	n/a	chrII 14,201,652	ace-4 encodes an divergent acetylcholinesterase homolog with biochemically undetectable activity.
48	glb-8	C26C6.7	n/a	chrI 7,510,602	glb-8 encodes a globin with no obvious function in mass RNAi assays; glb-8 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-8 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions; glb-8 expression is lower in L3 larvae than in young adults or dauers.
49	ptd-2	F07C3.1	n/a	chrV 9,252,223	C. elegans PTD-2 protein; contains similarity to Interpro domains IPR000731 (Sterol-sensing 5TM box), IPR006069 (ATPase, P-type cation exchange, alpha subunit)
50	Y102A5C.27	Y102A5C.27	n/a	chrV 16,988,446	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)