UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	flp-10	T06C10.4	2e-21	chrIV 7,869,261	flp-10 encodes a FMRFamide-related neuropeptide; in males, flp-10 activity is required for a sensory transduction pathway that negatively regulates the frequency of certain substeps of turning behavior during mating; a flp-10::gfp reporter is expressed in a number of neurons including AIM, ASI, AUA, BAG, BDU, DVB, PQR, PVR, and URX, and in the vulD cells.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C18D4.4	C18D4.4	n/a	chrV 17,530,973	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
4	K02E2.7	K02E2.7	n/a	chrV 20,380,450	contains similarity to Homo sapiens RB1-inducible coiled-coil protein 1; ENSEMBL:ENSP00000025008
5	C02F12.5	C02F12.5	n/a	chrX 3,671,203	C02F12.5 encodes a putatively secreted protein with a Kunitz/bovine pancreatic trypsin inhibitor domain; C02F12.5 has no obvious function in mass RNAi assays.
6	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	Y40H7A.11	Y40H7A.11	n/a	chrIV 15,219,977	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
8	fbxa-29	ZC47.3	n/a	chrIII 1,273,100	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
9	srx-20	R13H7.1	n/a	chrIV 6,868,598	C. elegans SRX-20 protein ;
10	F26A3.1	F26A3.1	n/a	chrI 7,641,050	contains similarity to Interpro domain IPR008262 (Lipase, active site)
11	R09D1.11	R09D1.11	n/a	chrII 9,467,636	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
12	str-102	R08H2.13	n/a	chrV 15,385,819	C. elegans STR-102 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	cyp-37B1	F28G4.1	n/a	chrV 16,279,374	C. elegans CYP-37B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
14	ZC196.1	ZC196.1	n/a	chrV 8,744,495
15	grl-3	K03B8.7	n/a	chrV 11,411,850	grl-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-3 is expressed in intestine, larval renal gland cells, and larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
16	str-183	T13F3.1	n/a	chrV 16,276,778	C. elegans STR-183 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	C10G8.3	C10G8.3	n/a	chrV 5,313,573	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domain IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
18	xtr-1	F54F7.4	n/a	chrX 11,852,038	xtr-1 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
19	C08B6.5	C08B6.5	n/a	chrV 10,118,697	contains similarity to Danio rerio Glutamate receptor delta-2 subunit precursor (GluR delta-2).; SW:Q68Y21
20	F14H3.12	F14H3.12	n/a	chrV 16,074,705	contains similarity to Pfam domain PF02149 Kinase associated domain 1 contains similarity to Interpro domain IPR001772 (Kinase-associated KA1)
21	B0507.6	B0507.6	n/a	chrV 8,749,589	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
22	ZK1307.9	ZK1307.9	n/a	chrII 9,650,113	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
23	W08F4.5	W08F4.5	n/a	chrII 567,279
24	R10H1.1	R10H1.1	n/a	chrII 7,495,254	contains similarity to Interpro domain IPR008374 (SF-assemblin)
25	F08F1.3	F08F1.3	n/a	chrX 8,430,035
26	K08D8.1	K08D8.1	n/a	chrIV 12,893,458	contains similarity to Fusobacterium nucleatum Tryptophanase (EC 4.1.99.1).; TR:Q8RHQ6
27	F21C10.4	F21C10.4	n/a	chrV 9,127,111	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
28	T25D10.4	T25D10.4	n/a	chrII 6,408,988
29	T15D6.8	T15D6.8	n/a	chrI 12,390,358	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
30	clec-15	T07D10.4	n/a	chrI 12,631,859	C. elegans CLEC-15 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
31	C24F3.2	C24F3.2	n/a	chrIV 10,223,062	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016278 (Tyrosine protein phosphatase, dual specificity, 12), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
32	srx-128	F55B12.7	n/a	chrV 13,838,056	C. elegans SRX-128 protein ;
33	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
34	nnt-1	C15H9.1	n/a	chrX 6,124,888	nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial.
35	T04A11.1	T04A11.1	n/a	chrIV 12,476,146	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
36	C03A7.12	C03A7.12	n/a	chrV 5,179,902	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
37	Y106G6D.6	Y106G6D.6	n/a	chrI 10,120,080	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
38	Y51B9A.8	Y51B9A.8	n/a	chrII 9,399,270	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01549 (ShK domain-like) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
39	ard-1	F01G4.2	n/a	chrIV 11,132,448	ard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial.
40	K12B6.8	K12B6.8	n/a	chrV 6,310,389	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
41	ZK673.3	ZK673.3	n/a	chrII 10,451,229	ZK673.3 encodes a protein with a THAP or THAP-like domain required for embryonic development; other proteins with THAP or THAP-like domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
42	sago-1	K12B6.1	n/a	chrV 6,306,024	sago-1 encodes an Argonaute homolog that is partially required for the amplification phase of RNAi responses; a multiply mutant strain (MAGO), consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894), F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, is completely resistant to both germline and somatic RNAi; sago-1 is genetically redundant with ppw-1 and sago-2, with any one of these genes being able to transgenically partially restore the deficiency of MAGO worms; GFP-tagged SAGO-1 binds small secondary siRNAs produced by RNAi against GFP; MAGO is not transgenically rescued by rde-1; strains overexpressing GFP::SAGO-1 exhibited an enhanced level of RNAi overall, suggesting that SAGO-1 and its congeners are rate-limiting in vivo for RNAi.
43	F48E8.3	F48E8.3	n/a	chrIII 5,462,687	contains similarity to Pfam domains PF00890 (FAD binding domain) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR010960 (Flavocytochrome c), IPR006076 (FAD dependent oxidoreductase), IPR003953 (Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal), IPR016040 (NAD(P)-binding)
44	C40C9.3	C40C9.3	n/a	chrX 13,647,897	contains similarity to Conus textile Conotoxin scaffold VI/VII.; TR:Q9U653
45	uev-3	F26H9.7	n/a	chrI 9,311,457	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
46	ZC190.10	ZC190.10	n/a	chrV 8,696,074
47	M176.8	M176.8	n/a	chrII 9,437,409	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
48	F39G3.6	F39G3.6	n/a	chrV 4,712,695	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
49	str-138	ZC513.11	n/a	chrV 8,059,468	C. elegans STR-138 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	R03D7.2	R03D7.2	n/a	chrII 10,933,886	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1