UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T05H10.4	T05H10.4	0	chrII 8,053,981	contains similarity to Saccharomyces cerevisiae Involved in cell-type-specific transcription and pheromone response; SGD:YMR043W
2	F32D8.4	F32D8.4	n/a	chrV 10,892,425	F32D8.4 is homologous to Yip1p, an essential Golgi membrane protein in S. cerevisiae that specifically binds the transport GTPases Ypt1p and Ypt31p, as well as Yop1p (the yeast homolog of human ADENOMATOUS POLYPOSIS COLI 1); F32D8.4 is also homologous to the Golgi membrane protein SB140 of H. sapiens, and contains a glutamine/asparagine-rich domain.
3	K06B9.2	K06B9.2	n/a	chrIV 4,192,443	K06B9.2 encodes a putative UDP-N-acetylglucosamine pyrophosphorylase, paralogous to C36A4.4 and orthologous to human UAP1 (OMIM:602862) and UAP1L1; K06B9.2 is thought to catalyse the fourth step of the hexosamine pathway to UDP-N-acetylglucosamine or UDP-N-acetylgalactosamine; K06B9.2 transcripts are enriched during oogenesis; K06B9.2(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, presumably because of defects in chitin and eggshell synthesis.
4	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
5	ZK643.2	ZK643.2	n/a	chrIII 8,957,012	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016473 (dCMP deaminase), IPR016193 (Cytidine deaminase-like), IPR015517 (Cytidine deaminase)
6	ZK632.11	ZK632.11	n/a	chrIII 9,828,713	contains similarity to Pfam domain PF04046 PSP contains similarity to Interpro domains IPR006568 (PSP, proline-rich), IPR001878 (Zinc finger, CCHC-type)
7	Y43E12A.3	Y43E12A.3	n/a	chrIV 10,988,514	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
8	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
9	tag-256	ZK637.3	n/a	chrIII 8,892,125	C. elegans TAG-256 protein ; contains similarity to Drosophila melanogaster Flybase gene name is CG7739-PA;; FLYBASE:CG7739
10	T05B11.4	T05B11.4	n/a	chrV 7,753,022	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
11	C17E7.4	C17E7.4	n/a	chrV 3,893,699
12	ZK643.5	ZK643.5	n/a	chrIII 8,954,457	contains similarity to Homo sapiens RNA binding motif protein 25; ENSEMBL:ENSP00000261973
13	F36A4.5	F36A4.5	n/a	chrIV 4,266,416	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
14	C13F10.2	C13F10.2	n/a	chrV 7,221,750	contains similarity to Drosophila melanogaster Flybase gene name is CG10681-PA;; FLYBASE:CG10681
15	T23D8.7	T23D8.7	n/a	chrI 9,991,647	contains similarity to Pfam domains PF02170 (PAZ domain) , PF08699 (Domain of unknown function (DUF1785)) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR014811 (Region of unknown function DUF1785), IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
16	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
17	T02C1.1	T02C1.1	n/a	chrIII 9,248,028	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR003613 (U box), IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
18	F19B10.2	F19B10.2	n/a	chrII 3,676,170
19	rnr-2	C03C10.3	n/a	chrIII 4,094,174	rnr-2 encodes the small subunit of ribonucleotide reductase; by homology, RNR-2 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-2 is an essential gene whose activity is required for reproduction and embryonic development.
20	fbxb-119	B0462.3	n/a	chrV 18,319,134	C. elegans FBXB-119 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
21	thoc-3	F32H2.4	n/a	chrI 8,972,046	C. elegans THOC-3 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
22	F31F6.2	F31F6.2	n/a	chrX 14,870,061	F31F6.2 encodes a novel protein that is conserved in C. elegans; three other genes related to F31F6.2 are present in tandem on the X chromosome; loss of F31F6.2 function via large-scale RNAi results in increased fat content.
23	K04C2.5	K04C2.5	n/a	chrIII 6,891,261
24	ugt-58	F35H8.6	n/a	chrII 9,585,502	C. elegans UGT-58 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
25	C54G4.9	C54G4.9	n/a	chrI 8,025,714	contains similarity to Pyrococcus furiosus Hypothetical protein PF0537.; TR:Q8U3D2
26	ZK856.12	ZK856.12	n/a	chrV 10,214,597	contains similarity to Homo sapiens similar to hypothetical protein FLJ12851; ENSEMBL:ENSP00000301962
27	F18C12.3	F18C12.3	n/a	chrI 8,097,075	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q54H40
28	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
29	F32E10.2	F32E10.2	n/a	chrIV 7,576,735	contains similarity to Pfam domain PF00385 'chromo' (CHRromatin Organisation MOdifier) domain contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
30	F52B5.2	F52B5.2	n/a	chrI 8,317,068	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
31	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
32	sdz-26	R06A4.6	n/a	chrII 14,382,371	C. elegans SDZ-26 protein; contains similarity to Pfam domain PF07149 Pes-10 contains similarity to Interpro domain IPR009819 (Pes-10)
33	K07F5.12	K07F5.12	n/a	chrIV 9,856,975	contains similarity to Pfam domain PF07857 CEO family (DUF1632) contains similarity to Interpro domain IPR012435 (Protein of unknown function DUF1632)
34	F01F1.11	F01F1.11	n/a	chrIII 5,870,989
35	T05E7.4	T05E7.4	n/a	chrI 6,193,727
36	hil-5	B0414.3	n/a	chrI 5,775,100	C. elegans HIL-5 protein; contains similarity to Pfam domain PF00538 linker histone H1 and H5 family contains similarity to Interpro domains IPR011991 (Winged helix repressor DNA-binding), IPR005819 (Histone H5), IPR000104 (Antifreeze protein, type I), IPR005818 (Histone H1/H5), IPR003216 (Linker histone, N-terminal)
37	F31F6.1	F31F6.1	n/a	chrX 14,867,621	F31F6.1 encodes a novel protein that is conserved in C. elegans; three other genes related to F31F6.1 are present in tandem on the X chromosome.
38	nasp-2	C50B6.2	n/a	chrV 13,311,278	C. elegans NASP-2 protein ; contains similarity to Halocynthia roretzi Protein HGV2.; SW:Q02508
39	pld-1	C04G6.3	n/a	chrII 5,087,755	C. elegans PLD-1 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF00614 (Phospholipase D Active site motif) (2), PF00787 (PX domain) contains similarity to Interpro domains IPR016555 (Phospholipase D, eukaryota), IPR001683 (Phox-like), IPR001849 (Pleckstrin-like), IPR001736 (Phospholipase D/Transphosphatidylase), IPR015679 (Phospholipase D)
40	lys-9	C54C8.6	n/a	chrI 12,455,280	C. elegans LYS-9 protein; contains similarity to Interpro domain IPR017853 (Glycoside hydrolase, catalytic core)
41	him-17	T09E8.2	n/a	chrV 13,178,423	him-17 encodes a protein with no obvious non-nematode homologs that localizes to chromatin in germline nuclei, and that is required for double-stranded break (DSB) formation, chiasmata, crossovers, and genetic recombination during meiosis, but is dispensable for homolog pairing and synapsis, spo-11 germline transcription, or the conversion of DSBs into chiasmata; HIM-17 is also required for normal organization of meiotic stages in the germline, and to promote its orderly transistion from (potentially tumorous) mitosis to meiosis; moreover, HIM-17 is required for normal dimethylation of lysine 9 residues on H3 histones in meiotic prophase chromosomes from early pachytene onward, with null him-17(ok424) mutants showing greatly reduced or delayed dimethylation in both hermaphrodite and male germlines; HIM-17 cooperates with GLP-1 to promote meiotic entry, and with EGO-1 to promote germline viability; HIM-17 has six THAP and THAP-like domains, a domain type also found in CDC-14B, CTB-1, GON-14, LIN-15A, LIN-15B, and LIN-36, along with ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1; missense or truncating mutations of HIM-17's THAP and THAP-like domains cause partial loss of function, implying that the domains collectively and partially contribute to HIM-17 activity; of the C. elegans genes encoding THAP or THAP-like domains, at least four (lin-15A, lin-15B, lin-36, and him-17) interact genetically with lin-35/Rb.
42	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
43	kbp-5	C34B2.2	n/a	chrI 10,687,701	C. elegans KBP-5 protein ;
44	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
45	tag-319	C30B5.1	n/a	chrII 6,200,135	C. elegans TAG-319 protein ;
46	zim-3	T07G12.11	n/a	chrIV 10,559,796	zmp-3 encodes a protein with two C-terminal noncanonical C2H2 zinc-fingers whose paralogs include HIM-8, ZIM-1/-2, and C02F5.12; ZIM-3 is specifically required for homolog pairing, synapsis, and segregation of chromosomes I and IV during meiosis; zim-3(tm2303) oocytes ending prophase have ~4 bivalents and ~4 univalents, the latter of which are consistently chromosomes I and IV; ZIM-3 associates with the right end of chromosome I and the left end of chromosome IV, which may indicate an association with their pairing centers; while the C-terminal region of ZIM-3 most closely resembles those of its orthologs in other Caenorhabditis species, its N-terminal region instead most closely resembles those of its paralogs in C. elegans, indicating coevolving, species-specific functions; ZIM-3 foci, like HIM-8 foci, associate with the nuclear envelope during meiotic prophase; zim-3 mutants also have some defective segregation of the X chromosome (yielding a Him phenotype), but this may be an indirect effect of autosomal asynapsis.
47	flh-3	Y11D7A.13	n/a	chrIV 9,270,834	C. elegans FLH-3 protein; contains similarity to Pfam domain PF04500 FLYWCH zinc finger domain contains similarity to Interpro domains IPR007588 (Zinc finger, FLYWCH-type), IPR009057 (Homeodomain-like)
48	C42D4.13	C42D4.13	n/a	chrIV 7,187,729	contains similarity to Interpro domain IPR004052 (Potassium channel, voltage dependent, Kv1.5)
49	tag-342	B0464.8	n/a	chrIII 9,468,896	C. elegans TAG-342 protein ;
50	T09E11.4	T09E11.4	n/a	chrI 12,361,669	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)