UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T05H10.1	T05H10.1	0	chrII 8,044,949	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR011051 (Cupin, RmlC-type)
2	nex-3	C28A5.3	n/a	chrIII 4,443,071	nex-3 encodes an annexin, a member of a family of calcium-dependent phospholipid binding proteins; by homology, NEX-3 could function in a number of processes, such as membrane fusion, cytoskeletal interactions, and intracellular signaling; however, as loss of nex-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of NEX-3 in C. elegans development and/or behavior is not yet known.
3	F46F11.8	F46F11.8	n/a	chrI 5,625,448
4	F56A8.4	F56A8.4	n/a	chrIII 13,264,008	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
5	F26H9.4	F26H9.4	n/a	chrI 9,306,326	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR005248 (Probable nicotinate-nucleotide adenylyltransferase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
6	D1086.4	D1086.4	n/a	chrV 14,091,601	contains similarity to Saccharomyces cerevisiae GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2; SGD:YAL035W
7	ZK418.8	ZK418.8	n/a	chrIII 7,084,302	contains similarity to Pfam domain PF00013 KH domain contains similarity to Interpro domains IPR009019 (K Homology, prokaryotic type), IPR004087 (K Homology), IPR004088 (K Homology, type 1)
8	sqv-3	R10E11.4	n/a	chrIII 9,779,478	sqv-3 encodes a beta(1,4)-galactosyltransferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos, vulval morphogenesis, and chondroitin synthesis; SQV-3 is orthologous to human human galactosyltransferase I (B4GALT7; OMIM:604327, mutated in the progeroid form of Ehlers-Danlos syndrome); sqv-3 transgenically rescues hamster cells lacking galactosyl transferase I; the common requirement for SQV-3 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
9	C42C1.8	C42C1.8	n/a	chrIV 12,292,136	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
10	F52C6.3	F52C6.3	n/a	chrII 1,925,233	contains similarity to Interpro domain IPR000626 (Ubiquitin)
11	F30F8.3	F30F8.3	n/a	chrI 7,836,374	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
12	fbxa-108	F59A1.7	n/a	chrV 17,657,524	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
13	F52C6.4	F52C6.4	n/a	chrII 1,923,563	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
14	fbxa-197	T06C12.4	n/a	chrV 15,868,291	C. elegans FBXA-197 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
15	F21F8.2	F21F8.2	n/a	chrV 8,275,167	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
16	T04A8.15	T04A8.15	n/a	chrIII 4,713,844	contains similarity to Saccharomyces cerevisiae Ubiquitin-specific protease; SGD:YDL122W
17	Y57G7A.8	Y57G7A.8	n/a	chrII 1,291,464
18	F33G12.2	F33G12.2	n/a	chrII 5,030,810	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
19	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
20	T14G10.7	T14G10.7	n/a	chrIV 10,148,080	contains similarity to Bos taurus GPI transamidase component PIG-S (Phosphatidylinositol-glycansbiosynthesis class S protein).; SW:Q3SZL5
21	ccdc-55	C16C10.6	n/a	chrIII 4,167,827	C. elegans CCDC-55 protein ; contains similarity to Mus musculus Coiled-coil domain-containing protein 55.; SW:Q5NCR9
22	F27B3.5	F27B3.5	n/a	chrIII 6,560,937	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
23	ulp-5	K02F2.4	n/a	chrI 6,813,375	C. elegans ULP-5 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
24	ZC410.3	ZC410.3	n/a	chrIV 9,077,529	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
25	F48E8.2	F48E8.2	n/a	chrIII 5,466,142	contains similarity to Mus musculus E2F-associated phosphoprotein (EAPP).; SW:Q5BU09
26	C56C10.9	C56C10.9	n/a	chrII 6,591,647	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
27	M05D6.2	M05D6.2	n/a	chrII 8,469,058	contains similarity to Pfam domain PF05794 T-complex protein 11 contains similarity to Interpro domain IPR008862 (T-complex 11)
28	zhp-3	K02B12.8	n/a	chrI 8,530,344	zhp-3 encodes a RING finger protein orthologous to budding yeast Cst9p (meiotically expressed) and human RNF212 (associated with varying recombination rate); ZHP-3 activity is required during meiosis for crossover recombination and chiasma formation; ZHP-3 activity is thus essential for proper chromosome segregation and normal levels of fertility; a ZHP-3::GFP fusion protein localizes along synapsed chromosomes in a manner that is dependent upon the presence of mature synaptonemal complexes; ZHP-3 is paralogous to D1081.9, F55A12.10, and Y39B6A.16.
29	C01G5.5	C01G5.5	n/a	chrIV 6,525,508	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
30	T01E8.4	T01E8.4	n/a	chrII 10,238,236	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains WD repeats.
31	T20D3.8	T20D3.8	n/a	chrIV 9,342,540	contains similarity to Pfam domain PF06432 Phosphatidylinositol N-acetylglucosaminyltransferase contains similarity to Interpro domain IPR009450 (Phosphatidylinositol N-acetylglucosaminyltransferase)
32	K11H3.3	K11H3.3	n/a	chrIII 9,852,736	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
33	C38D4.4	C38D4.4	n/a	chrIII 4,794,206	contains similarity to Saccharomyces cerevisiae Delayed Anaerobic Gene; SGD:YJR151C
34	srx-10	R10D12.4	n/a	chrV 13,945,845	C. elegans SRX-10 protein; contains similarity to Pfam domain PF08560 Protein of unknown function (DUF1757) contains similarity to Interpro domain IPR013869 (Protein of unknown function DUF1757)
35	tbx-36	ZK829.5	n/a	chrIV 11,951,305	C. elegans TBX-36 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
36	C07E3.9	C07E3.9	n/a	chrII 10,351,043	contains similarity to Pfam domain PF00068 Phospholipase A2 contains similarity to Interpro domains IPR016090 (Phospholipase A2), IPR001211 (Phospholipase A2, eukaryotic), IPR013090 (Phospholipase A2, active site)
37	C16C8.14	C16C8.14	n/a	chrII 3,450,118	C16C8.14 encodes a Caenorhabditis-specific protein, with a central predicted coiled-coil and a C-terminal ubiqutin-like domain; C16C8.14 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; C16C8.14 is paralogous to C16C8.4, C16C8.11, C16C8.12, C16C8.13, C16C8.15, C16C8.16, and F54D10.7.
38	srj-14	C03G6.3	n/a	chrV 7,371,464	C. elegans SRJ-14 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	glh-2	C55B7.1	n/a	chrI 6,515,665	glh-2 encodes a putative DEAD-box RNA helicase that contains six CCHC zinc fingers and is homologous to Drosophila VASA, a germ-line-specific, ATP-dependent, RNA helicase; at non-permissive temperatures, GLH-2 plays a role in germ-line development and fertility, specifically in regulating the normal extent of germ-line proliferation, oogenesis, and the production of functional sperm; GLH-2 activity may also be required for the wild-type morphology of P granules and for localization of several protein components, but not accumulation of P granule mRNA components; GLH-2 interacts in vitro with itself and with KGB-1, a JNK-like MAP kinase; GLH-2 is a constitutive P granule component and thus, with the exception of mature sperm, is expressed in germ cells at all stages of development; GLH-2 is cytoplasmic in oocytes and the early embryo, while perinuclear in all later developmental stages as well as in the distal and medial regions of the hermaphrodite gonad; GLH-2 is expressed at barely detectable levels in males.
40	C35D10.6	C35D10.6	n/a	chrIII 4,859,975	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
41	F14D2.8	F14D2.8	n/a	chrII 3,348,717	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
42	F57C9.7	F57C9.7	n/a	chrI 4,825,902
43	ZK742.2	ZK742.2	n/a	chrV 7,802,661	contains similarity to Homo sapiens Isoform 1 of Uncharacterized protein KIAA1530; ENSEMBL:ENSP00000374501
44	F26F12.2	F26F12.2	n/a	chrV 5,838,075
45	C16C8.13	C16C8.13	n/a	chrII 3,451,870	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
46	dnj-22	T23B12.7	n/a	chrV 8,461,579	This gene encodes a protein containing a DnaJ ('J') domain that is predicted to be mitochondrial.
47	K05C4.4	K05C4.4	n/a	chrI 14,736,077	contains similarity to Homo sapiens Hypothetical protein KIAA1185; ENSEMBL:ENSP00000253061
48	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	W03C9.2	W03C9.2	n/a	chrII 11,963,758	contains similarity to Schizosaccharomyces pombe Transcription elongation factor S-II (TFIIS).; SW:TFS2_SCHPO
50	B0545.4	B0545.4	n/a	chrIV 109,498	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)