UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pzf-1	T05G11.1	0	chrV 15,927,495	C. elegans PZF-1 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	rgs-10	F45B8.2	n/a	chrX 14,963,378	C. elegans RGS-10 protein; contains similarity to Pfam domain PF00615 Regulator of G protein signaling domain contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
4	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
5	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
6	F29C4.6	F29C4.6	n/a	chrIV 120,551	contains similarity to Pfam domain PF01171 PP-loop family contains similarity to Interpro domains IPR011063 (PP-loop), IPR012089 (PP-loop ATPase, YdaO-related), IPR000541 (Protein of unknown function UPF0021), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
7	msh-4	T02G5.6	n/a	chrII 7,078,297	C. elegans MSH-4 protein; contains similarity to Pfam domain PF00488 MutS domain V contains similarity to Interpro domain IPR000432 (DNA mismatch repair protein MutS, C-terminal)
8	F54D10.5	F54D10.5	n/a	chrII 3,807,652
9	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
10	C50E3.13	C50E3.13	n/a	chrV 7,623,254
11	E02H9.7	E02H9.7	n/a	chrIII 2,445,442	contains similarity to Homo sapiens Uncharacterized protein MUC17 (Fragment); ENSEMBL:ENSP00000368750
12	E02H4.6	E02H4.6	n/a	chrX 14,251,350	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
13	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
14	F14D7.2	F14D7.2	n/a	chrV 14,292,817	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
15	C27D9.1	C27D9.1	n/a	chrII 4,754,512	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
16	C31H1.8	C31H1.8	n/a	chrIV 5,812,882	contains similarity to Homo sapiens Protocadherin 15; ENSEMBL:ENSP00000378832
17	fem-3	C01F6.4	n/a	chrIV 9,106,267	fem-3 encodes a novel protein that promotes male development in all tissues.
18	C27C12.3	C27C12.3	n/a	chrX 14,864,682	C27C12.3 encodes a novel protein that is conserved in C. elegans; three other genes related to C27C12.3 are present in tandem on the X chromosome; in situ hybridization studies indicate that C27C12.3 mRNA is expressed in the proximal germline.
19	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
20	C27A7.6	C27A7.6	n/a	chrV 12,126,221	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
21	T25E12.5	T25E12.5	n/a	chrV 16,745,714	contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
22	cpar-1	F54C8.2	n/a	chrIII 9,434,486	cpar-1 encodes one of two C. elegans proteins homologous to the inner kinetochore histone H3 variant CENP-A (the other is encoded by hcp-3); loss of cpar-1 and hcp-3 activity via RNAi results in mitotic chromosome segregation defects, but no significant defects in meiotic chromosome segregation; when expressed in the germline using the pie-1 promoter, a CPAR-1::GFP fusion protein localizes to meiotic chromosomes during late prophase/prometaphase of meiosis I, but is not seen on chromosomes during meiosis II.
23	B0416.4	B0416.4	n/a	chrX 9,279,335	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR001841 (Zinc finger, RING-type), IPR000956 (Stathmin), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
24	C48B4.9	C48B4.9	n/a	chrIII 9,562,829	contains similarity to Arabidopsis thaliana Hypothetical protein (At1g32400/F5D14_22) (Tobamovirus multiplications2A).; TR:Q9C5W7
25	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
26	mel-47	EEED8.1	n/a	chrII 5,421,944	C. elegans MEL-47 protein; contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
27	nos-1	R03D7.7	n/a	chrII 10,952,444	nos-1 encodes an putative RNA-binding protein that contains a zinc-binding motif homologous to that of Drosophila Nanos, a posterior-group protein required for embryonic patterning and primordial germ cell development; in C. elegans, NOS-1 is required redundantly with NOS-2, a second Nanos homolog, for maintenance of germ cell viability during postembryonic development and for preventing primordial germ cells from dividing in the absence of food; nos-1 mRNA is expressed dynamically in the embryo, with early expression seen throughout the embryo and later expression restricted solely to germline blastomeres; nos-1 mRNA becomes undetectable after the 200-cell stage, but reappears later at the 550-cell stage; NOS-1 protein is not detectable in germline blastomeres until the 550-cell stage, suggesting that NOS-1 might actually function zygotically in germline specification.
28	C16A3.2	C16A3.2	n/a	chrIII 6,390,183	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
29	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
30	B0393.6	B0393.6	n/a	chrIII 4,781,174	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
31	cdk-1	T05G5.3	n/a	chrIII 9,747,971	cdk-1 encodes a cyclin-dependent kinase, orthologous to and functionally interchangeable with CDC28 from S. cerevisiae; CDK-1 is required for cell-cycle progression through M phase in both meiosis and mitosis.
32	C29A12.1	C29A12.1	n/a	chrV 10,812,876	contains similarity to Mesocricetus auratus Synaptonemal complex protein 1 (SCP-1 protein) (Meiotic chromosomessynaptic protein) (Fragment).; SW:SCP1_MESAU
33	C49C8.3	C49C8.3	n/a	chrIV 8,644,987
34	C04B4.2	C04B4.2	n/a	chrX 12,284,223	contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
35	ZC477.5	ZC477.5	n/a	chrIV 7,102,332
36	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
37	T19H5.4	T19H5.4	n/a	chrII 9,487,245	contains similarity to Gallus gallus Homeobox prospero-like protein PROX1 (PROX 1).; SW:PRX1_CHICK
38	R02F2.4	R02F2.4	n/a	chrIII 5,485,028	R02F2.4 encodes a protein with six chitin-binding peritrophin-A domains; R02F2.4 transcripts are enriched during oogenesis; like CEJ-1 and CPG-2, R02F2.4 might participate in eggshell synthesis and early embryonic development, and R02F2.4's multiple peritrophin-A domains might enable mechanical cross-linking of chitin; however, R02F2.4 has no obvious function in mass RNAi assays; while R02F2.4 is more closely similar to CPG-2 than CEJ-1, it may be less strongly expressed (since it has substantially fewer ESTs) and thus be less important in development.
39	F53F4.4	F53F4.4	n/a	chrV 13,596,162	contains similarity to Candida albicans Chitinase 3 precursor (EC 3.2.1.14).; SW:CHI3_CANAL
40	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
41	C17H11.4	C17H11.4	n/a	chrX 8,181,277	contains similarity to Drosophila melanogaster Flybase gene name is ari-1-PC;; FLYBASE:CG5659
42	F32D1.6	F32D1.6	n/a	chrV 4,374,245
43	zyg-11	C08B11.1	n/a	chrII 8,019,153	zyg-11 encodes a protein containing four diverged leucine-rich repeats and an armadillo-like helical domain and is conserved in metazoa, but not found in Drosophila; during development, ZYG-11 functions as the substrate-recognition subunit for a CUL-2-based ubiquitin-ligase complex that is required for a number of biological processes including progression through meiotic anaphase II, mitotic chromosome condensation, and establishment of anterior/posterior polarity in the early embryo; ZYG-11 interacts with CUL-2 in vivo and with ELC-1/elongin C in vitro.
44	ZK1320.7	ZK1320.7	n/a	chrII 9,672,350	contains similarity to Pfam domains PF00023 (Ankyrin repeat) , PF01585 (G-patch domain) contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR002110 (Ankyrin), IPR000467 (D111/G-patch)
45	T15D6.7	T15D6.7	n/a	chrI 12,387,268	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
46	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
47	gei-12	F52D2.4	n/a	chrX 1,988,059	gei-12 encodes a novel protein that affects embryonic viability and development of the hypodermis; interacts with GEX-3 in yeast two-hybrid assays, and is expressed in all somatic cells.
48	W06D11.1	W06D11.1	n/a	chrX 12,294,462
49	R06C7.2	R06C7.2	n/a	chrI 7,234,078	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86KG8
50	C17F4.5	C17F4.5	n/a	chrII 3,247,215	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.