UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T05E11.2	T05E11.2	6e-113	chrIV 11,115,881	T05E11.2 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; T05E11.2 is worm-specific, with a with highly divergent sequence lacking obvious homologs; T05E11.2 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
2	amt-2	F49E11.3	n/a	chrIV 13,044,619	amt-2 encodes a transmembrane protein that is one of four C. elegans members of the ammonium transporter AMT/Rh family of proteins predicted to function in transport of ammonium ions across the plasma membrane.
3	C01A2.6	C01A2.6	n/a	chrI 13,382,132	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q54BK4
4	srg-13	T23F11.5	n/a	chrIII 4,673,171	C. elegans SRG-13 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domains IPR001411 (Tetracycline resistance protein, TetB), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
5	ZK938.4	ZK938.4	n/a	chrII 9,835,995	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
6	sre-43	W07G1.6	n/a	chrII 13,967,710	C. elegans SRE-43 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
7	str-150	T03E6.4	n/a	chrV 16,584,195	C. elegans STR-150 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	str-217	Y102A5C.28	n/a	chrV 16,999,587	C. elegans STR-217 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	F28F9.3	F28F9.3	n/a	chrIV 3,831,378
10	hlh-14	C18A3.8	n/a	chrII 5,738,759	hlh-14 encodes a basic helix-loop-helix (bHLH) transcription factor that is one of five C. elegans Achaete-Scute family homologs; HLH-14 activity is required generally for normal egg-laying, movement, body morphology, and larval development; more specifically, HLH-14 is required for proper neuronal development, particularly for regulation of the asymmetric cell division that gives rise to the PVQ/HSN/PHB neuroblasts and for normal differentiation of these neuroblast descendants, including their cell division patterns, migrations, and neurotransmitter expression; in specifying neuronal cell fates, genetic evidence suggests that hlh-14 acts together with hlh-2, which encodes the C. elegans E/Daughterless ortholog; HLH-14 is expresed exclusively in the embryo and detected in the left and right PVQ/HSN/PHB neuroblasts and their descendants, as well as in other cells identified, tentatively, as anterior neuroblasts and posterior neuroblasts such as Caapa.
11	srh-192	ZC132.7	n/a	chrV 4,313,561	C. elegans SRH-192 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	F18E9.4	F18E9.4	n/a	chrX 8,582,026
13	F15D3.8	F15D3.8	n/a	chrI 11,580,950	contains similarity to Methanocaldococcus jannaschii Chromosome partition protein smc homolog.; SW:Q59037
14	K04F1.11	K04F1.11	n/a	chrV 1,660,979	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
15	E02C12.12	E02C12.12	n/a	chrV 9,380,457	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domain IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
16	F02E11.3	F02E11.3	n/a	chrII 3,273,416	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
17	C56G7.3	C56G7.3	n/a	chrIII 3,391,206	contains similarity to Pfam domain PF04727 ELMO/CED-12 family contains similarity to Interpro domain IPR006816 (Engulfment and cell motility, ELM)
18	spe-38	Y52B11A.1	n/a	chrI 10,965,401	C. elegans SPE-38 protein ;
19	str-97	F10A3.8	n/a	chrV 16,154,443	C. elegans STR-97 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	R10F2.5	R10F2.5	n/a	chrIII 2,924,200	contains similarity to Interpro domain IPR000443 (Islet amyloid polypeptide)
21	dmd-4	C27C12.6	n/a	chrX 14,859,502	C. elegans DMD-4 protein; contains similarity to Pfam domains PF00751 (DM DNA binding domain) , PF03474 (DMRTA motif) contains similarity to Interpro domains IPR005173 (DMRTA motif), IPR001275 (DM DNA-binding)
22	Y39E4B.13	Y39E4B.13	n/a	chrIII 13,092,265	contains similarity to Caulobacter crescentus Localization factor podJL (Polar organelle development protein)s[Contains: Localization factor podJS].; SW:PODJ_CAUCR
23	srr-2	T26H2.8	n/a	chrV 19,215,331	C. elegans SRR-2 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domains IPR004950 (Protein of unknown function DUF267, Caenorhabditis species), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
24	C16D9.6	C16D9.6	n/a	chrV 8,249,274	contains similarity to Drosophila melanogaster Flybase gene name is CG9520-PA;; FLYBASE:CG9520
25	srt-25	C16D9.7	n/a	chrV 8,257,371	C. elegans SRT-25 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	srd-60	C13B7.3	n/a	chrV 2,420,332	C. elegans SRD-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	F31B9.2	F31B9.2	n/a	chrX 15,919,200	contains similarity to Mus musculus Radixin (ESP10).; SW:RADI_MOUSE
28	T25E4.2	T25E4.2	n/a	chrII 5,581,240
29	E03G2.1	E03G2.1	n/a	chrX 15,927,754	contains similarity to Plasmodium falciparum Glutamate--cysteine ligase (EC 6.3.2.2).; TR:Q9TY17
30	ZK1225.2	ZK1225.2	n/a	chrI 13,209,439	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
31	C56G2.5	C56G2.5	n/a	chrIII 6,323,209	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR008973 (C2 calcium/lipid-binding region, CaLB)
32	fbxa-213	Y37H2C.3	n/a	chrV 18,268,033	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	srt-8	C50H11.2	n/a	chrV 3,087,272	C. elegans SRT-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
34	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
35	C04F12.8	C04F12.8	n/a	chrI 9,698,564	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
36	C50E3.7	C50E3.7	n/a	chrV 7,595,623	contains similarity to Interpro domain IPR001499 (Fungal pheromone STE3 GPCR)
37	W07G1.1	W07G1.1	n/a	chrII 13,938,717	contains similarity to Pfam domain PF03607 Doublecortin contains similarity to Interpro domain IPR003533 (Doublecortin)
38	F13A2.3	F13A2.3	n/a	chrV 4,394,967
39	srd-49	R04B5.8	n/a	chrV 10,095,486	C. elegans SRD-49 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
40	R12C12.4	R12C12.4	n/a	chrII 6,039,457
41	M03D4.6	M03D4.6	n/a	chrIV 6,144,282	contains similarity to Pfam domain PF02171 Piwi domain contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
42	nhr-169	C54C8.1	n/a	chrI 12,443,002	C. elegans NHR-169 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
43	F48B9.1	F48B9.1	n/a	chrX 2,183,370	contains similarity to Interpro domain IPR001220 (Legume lectin, beta domain)
44	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	aat-7	F54D12.3	n/a	chrII 1,389,233	aat-7 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-7 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-7 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
46	srh-142	T08G3.3	n/a	chrV 16,460,149	C. elegans SRH-142 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	F49C12.1	F49C12.1	n/a	chrIV 9,295,603	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
48	srw-23	F49A5.8	n/a	chrV 16,874,669	C. elegans SRW-23 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
49	Y51A2B.5	Y51A2B.5	n/a	chrV 18,390,243	contains similarity to Interpro domain IPR014044 (SCP-like extracellular)
50	str-252	C06B3.9	n/a	chrV 13,917,252	C. elegans STR-252 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR008365 (Prostanoid receptor), IPR003002 (7TM chemoreceptor, subfamily 1)