UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T05D4.2	T05D4.2	0	chrIII 13,562,369	contains similarity to Mus musculus Similar to SPEER 2.; TR:Q80ZP2
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	F43G6.5	F43G6.5	n/a	chrII 11,815,623	contains similarity to Pfam domains PF04926 (Poly(A) polymerase predicted RNA binding domain) , PF01909 (Nucleotidyltransferase domain) , PF04928 (Poly(A) polymerase central domain) contains similarity to Interpro domains IPR007012 (Poly(A) polymerase, central region), IPR002934 (Nucleotidyltransferase), IPR007010 (Poly(A) polymerase, RNA-binding region), IPR014492 (Poly(A) polymerase), IPR011068 (Nucleotidyltransferase, class I, C-terminal-like)
5	W04A8.5	W04A8.5	n/a	chrI 13,850,230	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	F31D5.6	F31D5.6	n/a	chrII 4,211,553	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
7	F58E1.12	F58E1.12	n/a	chrII 1,693,958
8	dct-13	Y116A8C.17	n/a	chrIV 17,024,680	Y116A8C.17 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of Y116A8C.17 is predicted to function as an RNA-binding protein.
9	R07C3.5	R07C3.5	n/a	chrII 931,761
10	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
11	egl-26	C23H3.1	n/a	chrII 70,469	egl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function.
12	M01E5.6	M01E5.6	n/a	chrI 13,299,460	contains similarity to Pfam domain PF02172 KIX domain contains similarity to Interpro domain IPR003101 (Coactivator CBP, KIX)
13	C24H12.1	C24H12.1	n/a	chrII 444,212	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
14	sdz-18	F45C12.11	n/a	chrII 1,705,740	C. elegans SDZ-18 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
15	taf-11.1	F48D6.1	n/a	chrX 4,255,964	C. elegans TAF-11.1 protein; contains similarity to Pfam domain PF04719 hTAFII28-like protein conserved region contains similarity to Interpro domains IPR006809 (TAFII28-like protein), IPR000104 (Antifreeze protein, type I), IPR009072 (Histone-fold)
16	R07C3.7	R07C3.7	n/a	chrII 916,765
17	T26E3.5	T26E3.5	n/a	chrI 12,663,411	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
18	hch-1	F40E10.1	n/a	chrX 14,698,114	hch-1 encodes a member of the zinc-dependent metalloprotease family that contains an epidermal growth factor-like domain, a CUB domain, and a TSP1 domain and affects hatching and QL neuroblast migration.
19	vet-6	F44F1.7	n/a	chrI 13,271,377	vet-6 encodes a protein that contains a spectrin repeat; vet-6 is preferentially transcribed in embryos prior to gastrulation.
20	R05H5.5	R05H5.5	n/a	chrII 10,200,234	contains similarity to Pfam domain PF04161 Arv1-like family contains similarity to Interpro domains IPR007290 (Arv1-like protein), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
21	C08F1.6	C08F1.6	n/a	chrII 1,787,707
22	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
23	F33E2.5	F33E2.5	n/a	chrI 12,591,727	contains similarity to Pyrococcus horikoshii Hypothetical protein PH1222.; TR:O58961
24	fbxb-57	F55C9.4	n/a	chrV 19,289,333	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
25	sdz-30	T04D3.2	n/a	chrI 13,307,433	C. elegans SDZ-30 protein; contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
26	ZK899.6	ZK899.6	n/a	chrX 9,463,973	contains similarity to Saccharomyces cerevisiae Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function; SGD:YPL195W
27	C07E3.6	C07E3.6	n/a	chrII 10,368,675	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
28	C24H12.8	C24H12.8	n/a	chrII 422,729	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
29	C02B8.2	C02B8.2	n/a	chrX 8,144,673
30	Y44A6C.2	Y44A6C.2	n/a	chrV 20,718,374	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I380
31	fbxb-61	F55C9.10	n/a	chrV 19,304,563	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
32	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
33	F55A3.3	F55A3.3	n/a	chrI 10,791,127	contains similarity to Pfam domains PF08512 (Histone chaperone Rttp106-like) , PF08644 (FACT complex subunit (SPT16/CDC68)) , PF00557 (metallopeptidase family M24) contains similarity to Interpro domains IPR013719 (Region of unknown function DUF1747, eukaryote), IPR000994 (Peptidase M24, catalytic core), IPR013953 (FACT complex subunit Spt16p/Cdc68p)
34	ZC395.11	ZC395.11	n/a	chrIII 5,286,154
35	C45G9.2	C45G9.2	n/a	chrIII 5,069,704	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR003733 (Thiamine monophosphate synthase), IPR001269 (Dihydrouridine synthase, DuS)
36	K01A2.9	K01A2.9	n/a	chrII 316,397	contains similarity to Interpro domain IPR002229 (Blood group Rhesus C/E and D polypeptide)
37	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
38	srj-37	F48G7.1	n/a	chrV 639,279	C. elegans SRJ-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	srw-53	T05G11.7	n/a	chrV 15,944,112	C. elegans SRW-53 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
40	K08H2.4	K08H2.4	n/a	chrX 13,239,283
41	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
42	sdz-38	ZK892.7	n/a	chrII 9,981,301	C. elegans SDZ-38 protein; contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
43	his-55	F54E12.1	n/a	chrIV 11,338,029	his-55 encodes an H3 histone; by homology, HIS-55 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-55 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
44	T11B7.1	T11B7.1	n/a	chrIV 8,841,747	contains similarity to Mus musculus Girdin (Girders of actin filament) (Coiled-coil domain-containingsprotein 88A) (Akt phosphorylation enhancer) (APE) (Hook-relatedsprotein 1) (HkRP1) (G alpha-interacting vesicle-associated protein)s(GIV).; SW:Q5SNZ0
45	psa-4	F01G4.1	n/a	chrIV 11,128,568	The psa-4 (phasmid socket absent) gene encodes an ortholog of SWI2/SNF2, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-4 is probably required during mitosis of the T cells for asymmetric cell division.
46	F26F4.6	F26F4.6	n/a	chrIII 4,892,477	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
47	F25B4.4	F25B4.4	n/a	chrV 5,685,274
48	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
49	F23D12.5	F23D12.5	n/a	chrX 14,450,814	F23D12.5 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; F23D12.5 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); F23D12.5 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, F23D12.5 has no obvious function in mass RNAi assays.
50	fzr-1	ZK1307.6	n/a	chrII 9,642,652	fzr-1 encodes a WD repeat-containing protein homologous to Cdh1/Hct1/FZR (OMIM:603619), a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C) required for anaphase initiation and exit from mitosis; FZR-1 is required for fertility, and also functions redundantly with lin-35/Rb to for normal embryogensis and control of postembryonic cell proliferation; FZR-1 probably regulates the levels of G1 cyclins, degradation of which is critical for G1 arrest.