UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T04F3.2	T04F3.2	7.000000000000001e-153	chrV 11,758,108	contains similarity to Pfam domain PF00086 Thyroglobulin type-1 repeat contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR000716 (Thyroglobulin type-1)
2	C07G3.2	C07G3.2	n/a	chrV 3,524,079	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
3	ncs-3	K03E6.3	n/a	chrX 1,055,449	ncs-3 encodes a neuronal calcium sensor (NCS) protein with no obvious null phenotype.
4	C32A3.2	C32A3.2	n/a	chrIII 3,629,439	contains similarity to Homo sapiens Kinesin-like protein KIF14; ENSEMBL:ENSP00000236917
5	atg-11	T08A9.1	n/a	chrX 7,337,446	T08A9.1 is orthologous to the human gene LIKELY ORTHOLOG OF MOUSE COILED COIL FORMING PROTEIN 1 (RB1CC1; OMIM:606837), which when mutated leads to disease.
6	nhr-100	C28D4.1	n/a	chrIV 9,729,825	nhr-100 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
7	tsp-20	B0198.1	n/a	chrX 12,032,731	C. elegans TSP-20 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
8	ptr-8	F44F4.4	n/a	chrII 10,891,194	ptr-8 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-8 is weakly required for normal molting from L4 to adult stages; PTR-8 is also required for normal growth to full size and locomotion; PTR-8 is expressed in hypodermis.
9	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
10	nhr-154	C13C4.2	n/a	chrV 12,102,273	C. elegans NHR-154 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	C06E2.1	C06E2.1	n/a	chrX 8,873,724	contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
12	fbxa-10	T12B5.3	n/a	chrIII 953,160	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
13	ser-5	F16D3.7	n/a	chrI 8,385,819	F16D3.7 encodes a homolog of mammalian alpha-adrenergic receptors that is expressed in vulval and bodywall muscle cells, intestine, and head neurons; heterologously expressed F16D3.7 has no effect on adenylate cyclase signalling; F16D3.7 has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
14	tsp-11	B0563.2	n/a	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
15	C53A5.9	C53A5.9	n/a	chrV 14,557,956	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF07646 (Kelch motif) (3), PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR004367 (Cyclin, C-terminal), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
16	tag-151	F10G7.1	n/a	chrII 4,711,891	C. elegans TAG-151 protein; contains similarity to Pfam domains PF08142 (AARP2CN (NUC121) domain) , PF04950 (Protein of unknown function (DUF663)) contains similarity to Interpro domains IPR012948 (AARP2CN), IPR007034 (Protein of unknown function DUF663)
17	nhr-226	T27B7.3	n/a	chrV 2,295,897	C. elegans NHR-226 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR000083 (Fibronectin, type I), IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	pmp-3	C54G10.3	n/a	chrV 14,650,313	pmp-3 encodes a putative ABC transporter orthologous to human ABCD4 (OMIM:603214) and paralogous to PMP-5; pmp-3 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; PMP-3 has no obvious function in mass RNAi assays, and pmp-3(ok1087) mutants are at least grossly normal (in particular, they show no defects in the uptake stage of RNAi).
19	C54D10.5	C54D10.5	n/a	chrV 12,430,253	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
20	F54D12.5	F54D12.5	n/a	chrII 1,370,835	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
21	F02H6.7	F02H6.7	n/a	chrIV 14,227,256	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
22	T02E1.8	T02E1.8	n/a	chrI 8,236,518
23	orai-1	C09F5.2	n/a	chrIII 653,677	C. elegans ORAI-1 protein; contains similarity to Pfam domain PF07856 Protein of unknown function (DUF1650) contains similarity to Interpro domain IPR012446 (Protein of unknown function DUF1650)
24	F31F7.2	F31F7.2	n/a	chrV 6,272,906	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
25	ZK1086.2	ZK1086.2	n/a	chrX 13,792,979	contains similarity to Shewanella oneidensis Hypothetical protein.; TR:Q8EJA6
26	srt-5	C50H11.14	n/a	chrV 3,080,169	C. elegans SRT-5 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
27	F08G12.3	F08G12.3	n/a	chrX 11,301,106	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5Q0
28	kqt-3	Y54G9A.3	n/a	chrII 13,704,530	kqt-3 encodes one of three C. elegans KCNQ-like potassium channel subunits and, with respect to humans, is most similar to the KCNQ1 channel protein which when mutated leads to inherited long QT syndrome (OMIM:607542); although loss of KQT-3 activity via large-scale RNAi screens results in no obvious abnormalities, KQT-3 likely functions to regulate cellular excitability as expression of KQT-3 in Xenopus oocytes can produce K+ channel currents that functionally resemble vertebrate M-currents; activity of these KQT-3 channels can be suppressed by coexpression with the human M1 muscarinic receptor and treatment with diacylglycerol analogs, although KQT-3 is less sensitive to each of these treatments than KQT-1; a KQT-3::GFP fusion protein is expressed in the anterior- and posterior-most intestinal cells, the anterior and posterior mechanosensory neurons ALM and PLM, amphid and phasmid neurons, and in some additional head neurons.
29	T22C8.7	T22C8.7	n/a	chrII 8,632,480	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
30	F58H1.4	F58H1.4	n/a	chrV 11,937,362	contains similarity to Interpro domain IPR006207 (Cystine knot, C-terminal)
31	cyp-23A1	B0304.3	n/a	chrII 4,514,151	The B0304.3 gene encodes a homolog of the human gene CYP7B1, which when mutated leads to giant cell hepatitis (OMIM:231100).
32	B0495.6	B0495.6	n/a	chrII 7,698,778	contains similarity to Pfam domain PF07189 Splicing factor 3B subunit 10 (SF3b10) contains similarity to Interpro domain IPR009846 (Splicing factor 3B subunit 5/RDS3 complex subunit 10)
33	ZC15.3	ZC15.3	n/a	chrV 20,299,636	contains similarity to Homo sapiens Myosin heavy chain, smooth muscle isoform; ENSEMBL:ENSP00000300036
34	C30A5.6	C30A5.6	n/a	chrIII 8,206,270
35	tag-224	B0496.8	n/a	chrIV 7,450,248	tag-224 encodes an ortholog of Drosophila CG6522-PA and of human LMCD1 and TESTIN; TAG-224 is dispensable for Wnt-directed planar cell polarity and the fully asymmetrical division of B.a versus B.p cells.
36	alh-10	C54D1.4	n/a	chrX 7,142,025	C. elegans ALH-10 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
37	str-46	C31B8.6	n/a	chrV 2,899,200	C. elegans STR-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	K02D3.2	K02D3.2	n/a	chrX 13,710,264	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
39	F54F7.7	F54F7.7	n/a	chrX 11,868,588	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
40	F47B7.6	F47B7.6	n/a	chrX 3,770,172
41	D2085.7	D2085.7	n/a	chrII 8,647,166
42	nhr-176	F14H3.11	n/a	chrV 16,072,040	C. elegans NHR-176 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
43	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
44	srx-16	T07H8.1	n/a	chrV 6,976,849	C. elegans SRX-16 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
45	soc-1	F41F3.2	n/a	chrV 4,644,923	C. elegans SOC-1 protein; contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
46	VC5.2	VC5.2	n/a	chrV 7,087,384	contains similarity to Pfam domain PF00053 Laminin EGF-like (Domains III and V) contains similarity to Interpro domains IPR006056 (YjgF-like protein), IPR006210 (EGF), IPR002049 (EGF-like, laminin)
47	unc-50	T07A5.2	n/a	chrIII 10,316,260	unc-50 encodes an integral membrane protein orthologous to the Saccharomyces cerevisiae Golgi component Gmh1p; UNC-50 is required for regulating subtype-specific nicotinic receptor trafficking to the cell surface and thus, for normal synaptic transmission at the neuromuscular junction; UNC-50 is ubiquitously expressed from early embryogenesis to adulthood and localizes to the Golgi.
48	F54E4.4	F54E4.4	n/a	chrX 14,643,359	contains similarity to Pfam domain PF03931 Skp1 family, tetramerisation domain contains similarity to Interpro domains IPR001232 (SKP1 component), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
49	C30F12.1	C30F12.1	n/a	chrI 6,957,790	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domain IPR000571 (Zinc finger, CCCH-type)
50	W10G11.4	W10G11.4	n/a	chrII 3,563,054	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)