UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dhs-31	T04B2.6	4e-142	chrIV 10,040,250	C. elegans DHS-31 protein; contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	T28A11.5	T28A11.5	n/a	chrV 3,270,895	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR003559 (Cytolethal distending toxin C), IPR002542 (Protein of unknown function DUF19)
4	F07C3.9	F07C3.9	n/a	chrV 9,254,456
5	ins-11	C17C3.4	n/a	chrII 5,556,897	ins-11 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-11 is one of 38 insulin-like peptides in C. elegans and is expressed in the labial sensory neurons, the nerve ring, and other neurons; although the precise role of INS-11 in C. elegans development is not yet clear, loss of INS-11 function via RNA-mediated interference can result in animals that are smaller than wild type (Sma).
6	C17B7.4	C17B7.4	n/a	chrV 3,339,687	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR003559 (Cytolethal distending toxin C), IPR002542 (Protein of unknown function DUF19)
7	dhs-26	ZK816.5	n/a	chrX 3,361,621	dhs-26 encodes a short-chain dehydrogenase predicted to be mitochondrial.
8	K01A2.10	K01A2.10	n/a	chrII 322,278	contains similarity to Homo sapiens Coiled-coil domain-containing protein 92; ENSEMBL:ENSP00000238156
9	F35F10.1	F35F10.1	n/a	chrV 3,317,203	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
10	gst-41	R13D7.7	n/a	chrV 7,398,864	C. elegans GST-41 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
11	C32F10.4	C32F10.4	n/a	chrI 5,809,249
12	C34F11.8	C34F11.8	n/a	chrII 5,210,353	contains similarity to Interpro domain IPR002952 (Eggshell protein)
13	C07A9.8	C07A9.8	n/a	chrIII 9,688,522	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
14	T28A11.16	T28A11.16	n/a	chrV 3,258,866	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
15	tag-243	T04A8.4	n/a	chrIII 4,686,618	C. elegans TAG-243 protein; contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)
16	F53A9.7	F53A9.7	n/a	chrX 8,716,682	contains similarity to Interpro domain IPR002395 (HMW kininogen)
17	F18G5.6	F18G5.6	n/a	chrX 9,263,128
18	F53F4.7	F53F4.7	n/a	chrV 13,613,185	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
19	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
20	F53A9.6	F53A9.6	n/a	chrX 8,713,583	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen)
21	F46A8.7	F46A8.7	n/a	chrI 11,238,164	contains similarity to Homo sapiens hypothetical protein MGC35285; ENSEMBL:ENSP00000279688
22	nlp-30	B0213.5	n/a	chrV 3,982,348	nlp-30 encodes five predicted neuropeptide-like proteins; in C. elegans, nlp-30 is part of the YGGWamide neuropeptide family that also contains nlp-24, nlp-25, and nlp-27-32; nlp-30 is expressed in the hypodermis, suggesting that the peptides it encodes may have a non-neuronal function; as loss of nlp-30 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-30-encoded peptides in development and/or behavior is not yet known.
23	flp-14	Y37D8A.15	n/a	chrIII 12,912,600	flp-14 encodes four copies of a single FMRFamide-related short peptide neurotransmitter; FLP-14 can increase pharyngeal action potential frequency, although its exact role in C. elegans neurotransmission is not yet clear.
24	srw-120	K12D9.5	n/a	chrV 2,995,551	C. elegans SRW-120 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
25	tag-38	B0222.4	n/a	chrV 9,145,742	C. elegans TAG-38 protein; contains similarity to Pfam domains PF00282 (Pyridoxal-dependent decarboxylase conserved domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
26	C17G10.7	C17G10.7	n/a	chrII 5,607,281
27	F48C1.8	F48C1.8	n/a	chrI 5,335,938	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
28	ins-4	ZK75.1	n/a	chrII 5,996,546	ins-4 encodes an insulin-like peptide.
29	C03G6.17	C03G6.17	n/a	chrV 7,380,393	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
30	col-114	D2024.8	n/a	chrIV 7,246,056	C. elegans COL-114 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
31	fbxa-24	F54D10.2	n/a	chrII 3,817,370	C. elegans FBXA-24 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
32	grd-9	C04E6.6	n/a	chrV 5,896,978	grd-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-9 is weakly required for normal molting; GRD-9 is also required for normal growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
33	K01D12.10	K01D12.10	n/a	chrV 12,406,600	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR003072 (Orphan nuclear receptor, NOR1 type), IPR003982 (Leukotriene B4 type 2 receptor)
34	F47B8.4	F47B8.4	n/a	chrV 14,324,002	contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR012336 (Thioredoxin-like fold)
35	gst-22	F21H7.1	n/a	chrV 16,231,635	C. elegans GST-22 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
36	C36C5.12	C36C5.12	n/a	chrV 3,158,933	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
37	thn-2	F28D1.5	n/a	chrIV 12,383,557	C. elegans THN-2 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
38	fbxa-164	C08E3.7	n/a	chrII 1,613,450	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
39	C32H11.3	C32H11.3	n/a	chrIV 12,919,384	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
40	T19D12.3	T19D12.3	n/a	chrII 6,660,581
41	F48G7.2	F48G7.2	n/a	chrV 637,034
42	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
43	flp-24	C24A1.1	n/a	chrIII 725,550	C. elegans FLP-24 protein ;
44	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
45	F07C4.10	F07C4.10	n/a	chrV 7,639,387	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
46	Y38H6C.19	Y38H6C.19	n/a	chrV 20,548,064	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
47	F58E6.4	F58E6.4	n/a	chrV 9,750,160	contains similarity to Homo sapiens Protein PRO1073/PRO2853; ENSEMBL:ENSP00000332769
48	T04A11.4	T04A11.4	n/a	chrIV 12,483,683	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
49	C08F11.3	C08F11.3	n/a	chrIV 13,620,866	contains similarity to Homo sapiens HOR5'Beta8; ENSEMBL:ENSP00000332473
50	ttr-1	K03H1.6	n/a	chrIII 9,929,635	ttr-1 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although TTR-1 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of ttr-1 function via RNAi can result in enhanced dauer formation and daf-16-dependent lifespan extension.