UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T03G11.3	T03G11.3	3e-156	chrX 5,175,968	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
2	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	F16H11.2	F16H11.2	n/a	chrX 4,662,854	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23LR2
5	M01F1.7	M01F1.7	n/a	chrIII 3,525,420	M01F1.7 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); M01F1.7 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; while M01F1.7 would be expected to mediate PIP(2) signalling in either neuronal function or cytokinesis, it has not yet had a published mutant phenotype, and has no obvious function in mass RNAi assays.
6	dhs-16	C10F3.2	n/a	chrV 5,984,592	dhs-16 encodes a short-chain dehydrogenase predicted to be mitochondrial.
7	C35A11.1	C35A11.1	n/a	chrV 5,406,834	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
8	F14H8.4	F14H8.4	n/a	chrV 15,024,402	contains similarity to Clostridium acetobutylicum Protein containing a domain related to multimeric flavodoxin WrbAsfamily.; TR:Q97H25
9	elc-2	W03H1.2	n/a	chrX 1,777,746	elc-2 encodes a protein containing a Skp1 dimerisation domain that has homology to human transcription elongation factor B (SIII), polypeptide I (15kD, elonginsC).
10	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
11	R08F11.7	R08F11.7	n/a	chrV 3,791,935	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
12	F07E5.9	F07E5.9	n/a	chrII 2,077,849	contains similarity to Interpro domain IPR016160 (Aldehyde dehydrogenase, conserved site)
13	egrh-1	C27C12.2	n/a	chrX 14,847,486	C27C12.2 is orthologous to the human gene BA436D10.3 (EARLY GROWTH RESPONSE 2 (KROX-20 (DROSOPHILA) HOMOLOG)) (EGR2; OMIM:129010), which when mutated leads to disease.
14	C27F2.1	C27F2.1	n/a	chrIII 4,989,295	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
15	F28D1.6	F28D1.6	n/a	chrIV 12,384,958	contains similarity to Neurospora crassa ATP-dependent RNA helicase dbp-8 (EC 3.6.1.-).; SW:Q7RYZ7
16	C06B3.7	C06B3.7	n/a	chrV 13,910,615	contains similarity to Streptococcus agalactiae Tn5252, relaxase.; TR:Q8DZ67
17	sru-40	R07B5.3	n/a	chrV 9,833,347	C. elegans SRU-40 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
18	nhr-220	T19H12.8	n/a	chrV 4,883,423	C. elegans NHR-220 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	nhr-167	C49F5.4	n/a	chrX 11,981,020	C. elegans NHR-167 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
20	srd-1	F33H1.5	n/a	chrII 10,181,388	srd-1 encodes a seven transmembrane chemosensory receptor; SRD-1 is expressed in the ASI chemosensory neurons; SRD-1 expression in ASI is repressed in the presence of dauer pheromone at concentrations lower than that which induces dauer formation.
21	C25E10.11	C25E10.11	n/a	chrV 9,057,966
22	T11F9.14	T11F9.14	n/a	chrV 11,480,742	contains similarity to Oryctolagus cuniculus Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).; SW:TRIF_RABIT
23	F43G6.7	F43G6.7	n/a	chrII 11,811,141	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003980 (Histamine H3 receptor)
24	inx-6	C36H8.2	n/a	chrIV 12,748,113	inx-6 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; INX-6 is required for formation of pharyngeal gap junctions and thus for the electrical coupling and synchronous muscle contractions necessary for normal feeding behavior and postembryonic development; INX-6 may function redundantly with EAT-5, another C. elegans innexin; INX-6 expression is first detected in embryonic pharyngeal precursors and during later larval and adult stages, in pharyngeal corpus muscles and isthmus marginal cells, where INX-6 localizes to plaque-like structures in the plasma membrane.
25	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
26	C25B8.5	C25B8.5	n/a	chrX 6,633,438	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
27	F22D6.8	F22D6.8	n/a	chrI 7,099,204
28	F55D12.1	F55D12.1	n/a	chrI 7,884,957	contains similarity to Brachydanio rerio Hypothetical protein.; TR:Q803L4
29	F15A8.1	F15A8.1	n/a	chrX 4,441,526
30	F53G12.11	F53G12.11	n/a	chrI 145,479	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
31	F45E1.1	F45E1.1	n/a	chrX 8,008,286
32	F28G4.4	F28G4.4	n/a	chrV 16,284,328	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR005069 (Protein of unknown function DUF271)
33	srh-174	F40D4.1	n/a	chrV 17,179,348	C. elegans SRH-174 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	F38C2.4	F38C2.4	n/a	chrIV 16,270,980	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
35	srw-4	F37B4.8	n/a	chrV 2,887,985	C. elegans SRW-4 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
36	lgc-55	Y113G7A.5	n/a	chrV 20,025,213	C. elegans LGC-55 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR013032 (EGF-like region, conserved site), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
37	gpa-3	E02C12.5	n/a	chrV 9,358,223	gpa-3 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects dauer formation, water-soluble chemoattraction and chemoaversion, and volatile chemoattraction; it is expressed in amphid and phasmid neurons and some interneurons.
38	Y38H6C.17	Y38H6C.17	n/a	chrV 20,537,681	Y38H6C.17 encodes a putative amino acid transporter that inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; Y38H6C.17 has 11 predicted transmembrane alpha-helices; Y38H6C.17 has multiple C. elegans paralogs and non-nematode orthologs, including budding yeast AVT3 and AVT4 and human SLC36A1 (OMIM:606561).
39	C28F5.4	C28F5.4	n/a	chrII 7,521,547	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
40	fbxa-3	T08E11.7	n/a	chrII 1,819,483	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
41	F45E12.6	F45E12.6	n/a	chrII 7,313,979
42	srz-70	C09G12.6	n/a	chrIV 3,478,198	C. elegans SRZ-70 protein ;
43	F14B6.2	F14B6.2	n/a	chrI 12,220,319	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
44	Y54E2A.10	Y54E2A.10	n/a	chrII 14,791,729	contains similarity to Dictyostelium discoideum Protein-tyrosine phosphatase 3 (EC 3.1.3.48) (Protein-tyrosine-sphosphate phosphohydrolase 3).; SW:PTP3_DICDI
45	ttr-13	Y44A6B.4	n/a	chrV 20,631,647	C. elegans TTR-13 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
46	srx-45	K01B6.2	n/a	chrIII 9,305,269	C. elegans SRX-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
47	ZC317.2	ZC317.2	n/a	chrV 5,460,748
48	K08F9.3	K08F9.3	n/a	chrV 15,143,291	contains similarity to Pfam domains PF00168 (C2 domain) (3), PF08165 (FerA (NUC095) domain) , PF08150 (FerB (NUC096) domain) contains similarity to Interpro domains IPR012561 (FerB), IPR006614 (Dysferlin, C-terminal), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR012560 (FerA), IPR006613 (Dysferlin, N-terminal), IPR000008 (C2 calcium-dependent membrane targeting)
49	str-87	F59E11.16	n/a	chrV 8,987,304	C. elegans STR-87 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	ZK1067.4	ZK1067.4	n/a	chrII 9,211,645	ZK1067.4 is orthologous to the human gene PROTEOLIPID PROTEIN 1 (PLP1; OMIM:300401), encoding the primary constituent of myelin, which when mutated leads to Pelizaeus-Merzbacher disease (OMIM:312080).