UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	str-150	T03E6.4	1e-179	chrV 16,584,195	C. elegans STR-150 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	sre-43	W07G1.6	n/a	chrII 13,967,710	C. elegans SRE-43 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
3	F31A9.1	F31A9.1	n/a	chrX 1,797,616
4	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	T05E11.2	T05E11.2	n/a	chrIV 11,115,881	T05E11.2 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; T05E11.2 is worm-specific, with a with highly divergent sequence lacking obvious homologs; T05E11.2 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
6	T25E4.2	T25E4.2	n/a	chrII 5,581,240
7	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.
8	C56G7.3	C56G7.3	n/a	chrIII 3,391,206	contains similarity to Pfam domain PF04727 ELMO/CED-12 family contains similarity to Interpro domain IPR006816 (Engulfment and cell motility, ELM)
9	F49D11.2	F49D11.2	n/a	chrI 10,922,443	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
10	K12C11.3	K12C11.3	n/a	chrI 1,336,076	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
11	srd-60	C13B7.3	n/a	chrV 2,420,332	C. elegans SRD-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	snt-6	C08G5.4	n/a	chrII 747,906	C. elegans SNT-6 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
13	ZK1225.2	ZK1225.2	n/a	chrI 13,209,439	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
14	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
15	C17A2.3	C17A2.3	n/a	chrII 3,844,552	contains similarity to Drosophila melanogaster Flybase gene name is CG2975-PA;; FLYBASE:CG2975
16	srw-23	F49A5.8	n/a	chrV 16,874,669	C. elegans SRW-23 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
17	nas-39	F38E9.2	n/a	chrX 16,464,603	C. elegans NAS-39 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) (2), PF00431 (CUB domain) (4), PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR015446 (Bone morphogenetic protein 1/tolloid-like protein), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR001506 (Peptidase M12A, astacin), IPR006210 (EGF), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding)
18	C18D1.2	C18D1.2	n/a	chrII 10,057,912	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
19	inx-20	T23H4.1	n/a	chrI 9,877,813	C. elegans INX-20 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
20	srz-61	K03D3.4	n/a	chrIV 16,322,140	C. elegans SRZ-61 protein ;
21	C01A2.6	C01A2.6	n/a	chrI 13,382,132	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q54BK4
22	F28F9.3	F28F9.3	n/a	chrIV 3,831,378
23	srf-3	M02B1.1	n/a	chrIV 12,852,213	C. elegans SRF-3 protein; contains similarity to Pfam domains PF08449 (UAA transporter family) , PF04142 (Nucleotide-sugar transporter) contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR013657 (UAA transporter), IPR007271 (Nucleotide-sugar transporter)
24	F41E6.1	F41E6.1	n/a	chrV 8,624,595
25	srh-192	ZC132.7	n/a	chrV 4,313,561	C. elegans SRH-192 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	srb-17	F01D4.7	n/a	chrIV 10,455,510	C. elegans SRB-17 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
27	srh-142	T08G3.3	n/a	chrV 16,460,149	C. elegans SRH-142 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	spe-38	Y52B11A.1	n/a	chrI 10,965,401	C. elegans SPE-38 protein ;
29	F59H6.2	F59H6.2	n/a	chrII 2,021,048
30	C54E4.4	C54E4.4	n/a	chrIV 2,163,172
31	che-12	B0024.8	n/a	chrV 10,303,399	che-12 encodes a conserved protein that contains at least seven predicted HEAT repeats; CHE-12 activity is required continuously in sensory neurons for formation of distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis to a subset of attractants, including sodium chloride; a che-12::gfp promoter fusion is expressed in the two phasmid neurons and the subset of amphid neurons that contain relatively simple cilia; a CHE-12::GFP protein localizes to cilia in a manner suggesting that it requires intraflagellar transport for proper localization, but is unlikely to be a core IFT particle component; che-12 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor.
32	srbc-2	C04E12.9	n/a	chrV 3,375,717	C. elegans SRBC-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
33	clec-3	C41H7.7	n/a	chrII 3,018,651	C. elegans CLEC-3 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
34	Y51A2B.5	Y51A2B.5	n/a	chrV 18,390,243	contains similarity to Interpro domain IPR014044 (SCP-like extracellular)
35	Y43F8C.11	Y43F8C.11	n/a	chrV 19,670,774	contains similarity to Mus sp Interleukin-3 receptor beta subunit (Fragment).; TR:Q64130
36	C18D11.1	C18D11.1	n/a	chrIII 11,818,072	contains similarity to Sporobolus stapfianus Hypothetical protein.; TR:O04820
37	W03F9.4	W03F9.4	n/a	chrV 149,461	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domains IPR000542 (Acyltransferase ChoActase/COT/CPT), IPR001644 (C3A-anaphylatoxin receptor)
38	F38B6.7	F38B6.7	n/a	chrX 6,697,033	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
39	F16G10.13	F16G10.13	n/a	chrII 2,395,441	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
40	F08G12.5	F08G12.5	n/a	chrX 11,309,490	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
41	C17B7.9	C17B7.9	n/a	chrV 3,331,512	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
42	aqp-6	C32C4.2	n/a	chrV 10,651,251	apq-6 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability five- to seven-fold; aqp-6 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-5; AQP-6 is expressed in the cilia and cell bodies of IL1 sensory neurons; AQP-6 is orthologous to human AQP8 (OMIM:603750).
43	T24D5.1	T24D5.1	n/a	chrX 12,575,561	contains similarity to Melanoplus sanguinipes entomopoxvirus ORF MSV156 hypothetical protein.; TR:Q9YVT6
44	F08F3.1	F08F3.1	n/a	chrV 5,447,387
45	F55F1.2	F55F1.2	n/a	chrX 2,769,819
46	nhr-194	F59E11.8	n/a	chrV 8,969,321	C. elegans NHR-194 protein; contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
47	F56C9.8	F56C9.8	n/a	chrIII 7,317,655
48	clec-114	C49A1.9	n/a	chrI 14,233,796	C. elegans CLEC-114 protein; contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
49	bbs-9	C48B6.8	n/a	chrI 6,920,270	C. elegans BBS-9 protein ; contains similarity to Homo sapiens 95 kDa protein; ENSEMBL:ENSP00000346214
50	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)