UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T02G6.2	T02G6.2	0	chrI 11,801,906	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9C9Y9
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	tag-19	C09G9.4	n/a	chrIV 8,875,605	tag-19 superficially resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, it is distantly related, being no closer to them than to glutamine decarboxylase/sphingosinge lyase (e.g., tag-38, spl-1); tag-19 thus might be termed a Pyridoxal-phosphate (PLP) dependent decarboxylase-like protei, but is missing the absolutely conserved Lys residue of all PLP-DCs (hence the -like would be needed); tag-19 is dispensable in mass RNAi assays.
4	F36D1.6	F36D1.6	n/a	chrI 11,270,696	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
5	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
6	Y113G7A.12	Y113G7A.12	n/a	chrV 20,140,914
7	C06C3.9	C06C3.9	n/a	chrII 9,377,271
8	H12D21.5	H12D21.5	n/a	chrV 14,894,419	contains similarity to Interpro domains IPR001307 (Thiosulfate sulfurtransferase), IPR000463 (Cytosolic fatty-acid binding protein), IPR001763 (Rhodanese-like)
9	try-6	F48A9.3	n/a	chrI 6,586,594	C. elegans TRY-6 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
10	fbxa-96	H03G16.4	n/a	chrX 15,059,361	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
11	unc-79	E03A3.6	n/a	chrIII 4,074,729	unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with nca-1 and nca-2, which encode ion channel subunits, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of NCA-1 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults.
12	W03D8.3	W03D8.3	n/a	chrI 2,821,478	contains similarity to Interpro domain IPR000694 (Proline-rich region)
13	ceh-6	K02B12.1	n/a	chrI 8,500,257	ceh-6 encodes a POU family homeodomain protein, homologous to human POU3F4 (OMIM:304400, mutated in conductive deafness 3) that affects embryonic viability, locomotion, and molting, and that regulates ectodermal and excretory function; CEH-6 is expressed dynamically during development and expression includes neurons, the excretory cell, and ectodermal cells.
14	T09B4.3	T09B4.3	n/a	chrI 6,177,087
15	F37C4.1	F37C4.1	n/a	chrIV 3,890,907	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
16	F54D12.7	F54D12.7	n/a	chrII 1,383,599	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
17	srb-19	C54F6.11	n/a	chrV 7,518,912	C. elegans SRB-19 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
18	Y47H9B.2	Y47H9B.2	n/a	chrI 11,745,783	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
19	C03B1.6	C03B1.6	n/a	chrX 6,350,637
20	Y41C4A.1	Y41C4A.1	n/a	chrIII 11,648,712	contains similarity to Oryza sativa Putative aspartate kinase.; TR:Q851Z6
21	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
22	F07C3.2	F07C3.2	n/a	chrV 9,226,731
23	F10D7.4	F10D7.4	n/a	chrX 17,380,140
24	F46F5.11	F46F5.11	n/a	chrII 810,328	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
25	sri-36	F33H12.5	n/a	chrII 2,584,688	C. elegans SRI-36 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	K06B4.3	K06B4.3	n/a	chrV 15,672,799	contains similarity to Saccharomyces cerevisiae mRNA binding protein; SGD:YPR042C
27	sra-38	T21H8.3	n/a	chrX 13,898,963	C. elegans SRA-38 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
28	ZC404.7	ZC404.7	n/a	chrV 6,779,108
29	F28C10.4	F28C10.4	n/a	chrX 539,044
30	col-132	C39E9.9	n/a	chrIV 13,090,324	C. elegans COL-132 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
31	ceh-12	F33D11.4	n/a	chrI 5,841,090	ceh-12 encodes a homeobox protein orthologous to human HLXB9 (OMIM:142994, mutated in Currarino syndrome) that is required for normal synaptic inputs to motor neurons VA2-VA10 (sisters to VB3-VB11); ceh-12 is expressed in VB motor neurons, but repressed in their VA siblings by UNC-4 and UNC-37; unc-4 or unc-37 mutants show ectopic CEH-12 expression in VA neurons, which is both necessary and sufficient to induce VA neurons to form gap junctions with normally VB-specific interneurons; ceh-12 mutations have no grossly obvious phenotype, and have no effect on del-1 or acr-5 repression in VB neurons, but do suppress the backward movement defect of unc-4 mutants, and do derepress vab-7 (normally restricted to DB and VC motor neurons); CEH-12, like other HLXB9 orthologs, has an N-terminal eh1 domain that may interact with UNC-37/Groucho, and that may indicate CEH-12 to be a transcriptional repressor.
32	C31H1.2	C31H1.2	n/a	chrIV 5,792,361	contains similarity to Pfam domain PF02013 Cellulose or protein binding domain contains similarity to Interpro domains IPR003616 (Post-SET zinc-binding region), IPR000215 (Protease inhibitor I4, serpin), IPR002883 (Dockerin, cellulose-binding family V)
33	Y113G7B.11	Y113G7B.11	n/a	chrV 20,209,977	contains similarity to Naja atra Cardiotoxin 10 precursor.; TR:Q9W6W6
34	T05A1.3	T05A1.3	n/a	chrIV 9,563,673	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
35	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
36	T11A5.1	T11A5.1	n/a	chrV 9,859,109	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR008162 (Inorganic pyrophosphatase)
37	lact-1	F46H5.8	n/a	chrX 7,259,241	lact-1 encodes a beta-lactamase domain-containing protein.
38	ZK418.6	ZK418.6	n/a	chrIII 7,076,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000694 (Proline-rich region), IPR000276 (GPCR, rhodopsin-like)
39	F35B3.7	F35B3.7	n/a	chrX 17,038,997	contains similarity to Homo sapiens Leucine zipper putative tumor suppressor 2; ENSEMBL:ENSP00000359240
40	sru-22	F36G9.5	n/a	chrV 15,973,922	C. elegans SRU-22 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
41	B0207.11	B0207.11	n/a	chrI 5,963,581	B0207.11 encodes a nematode-specific protein probably required for a normally high ovulation rate; B0207.11 has no obvious non-nematode homologs, but does have a putative N-terminal coiled-coil domain and an SH2 motif, and is is paralogous to four other C. elegans proteins (F42G4.6, F44F4.10, T08G11.2, and Y81G3A.1); B0207.11(tm322) hermaphrodites show abnormal egg-laying, retaining significantly fewer eggs than wild-type (perhaps due to a lowered ovulation rate) while retaining late-stage embryos; B0207.11 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs.
42	T11F1.2	T11F1.2	n/a	chrII 2,957,123	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
43	T06E4.5	T06E4.5	n/a	chrV 9,631,723	contains similarity to Interpro domains IPR001046 (Natural resistance-associated macrophage protein), IPR001266 (Ribosomal protein S19e)
44	C44B11.1	C44B11.1	n/a	chrIII 3,156,820	contains similarity to Pfam domain PF06905 Fas apoptotic inhibitory molecule (FAIM1) contains similarity to Interpro domain IPR010695 (Fas apoptotic inhibitory molecule)
45	W02D7.3	W02D7.3	n/a	chrV 8,294,341
46	srt-44	M199.1	n/a	chrIV 15,105,017	C. elegans SRT-44 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	Y18D10A.3	Y18D10A.3	n/a	chrI 12,812,894	contains similarity to Pfam domain PF03853 YjeF-related protein N-terminus contains similarity to Interpro domain IPR004443 (YjeF-related protein, N-terminal)
48	K02D10.3	K02D10.3	n/a	chrIII 8,771,549
49	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
50	nhr-39	F44A2.4	n/a	chrV 9,303,947	C. elegans NHR-39 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)