UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T02G5.2	T02G5.2	7e-144	chrII 7,095,853	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001023 (Heat shock protein Hsp70)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	ceh-36	C37E2.4	n/a	chrX 14,184,445	ceh-36 encodes a paired-like homeodomain transcription factor that is one of three orthodenticle (OTD)-like homeodomain proteins in C. elegans (the others being ttx-1 and ceh-37); CEH-36 is required broadly for specification of the AWC olfactory neuron and also for establishing the left-right asymmetry of the ASEL and ASER gustatory neurons; in addition, CEH-36 is sufficient to specify the AFD thermosensory neuron fate in some cell types; CEH-36 is expressed in the AWC and ASE chemosensory neurons.
4	F53G2.1	F53G2.1	n/a	chrII 2,492,698	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
5	str-118	F57A8.3	n/a	chrV 10,052,955	C. elegans STR-118 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	clec-18	F56H6.8	n/a	chrI 12,302,280	C. elegans CLEC-18 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
7	mdt-31	F32H2.2	n/a	chrI 8,966,630	C. elegans MDT-31 protein; contains similarity to Pfam domain PF05669 SOH1 contains similarity to Interpro domain IPR008831 (SOH1)
8	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
9	Y116A8B.1	Y116A8B.1	n/a	chrIV 17,216,790	contains similarity to Oryza sativa P0660F12.13 protein (P0614D08.10 protein).; TR:Q94CR6
10	F36H5.4	F36H5.4	n/a	chrII 1,762,375
11	C35A11.3	C35A11.3	n/a	chrV 5,374,943	contains similarity to Homo sapiens Uncharacterized protein MUC5AC (Fragment); ENSEMBL:ENSP00000371671
12	K10C3.4	K10C3.4	n/a	chrI 9,861,391	contains similarity to Xenopus laevis Transmembrane protein 98.; SW:Q6INX1
13	srx-47	E02C12.3	n/a	chrV 9,350,632	C. elegans SRX-47 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
14	clec-231	C29F3.4	n/a	chrV 15,350,031	C. elegans CLEC-231 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
15	F55A4.3	F55A4.3	n/a	chrX 1,023,626
16	ZK899.6	ZK899.6	n/a	chrX 9,463,973	contains similarity to Saccharomyces cerevisiae Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function; SGD:YPL195W
17	Y53C12B.2	Y53C12B.2	n/a	chrII 9,740,855	contains similarity to Pfam domain PF00013 KH domain contains similarity to Interpro domains IPR004087 (K Homology), IPR004088 (K Homology, type 1)
18	air-2	B0207.4	n/a	chrI 5,938,181	air-2 encodes an aurora/Ipl1-related serine/threonine protein kinase that affects embryonic viability and chromosome segregation during meiosis and mitosis and is required for cytokinesis; AIR-2 has two functions during mitosis, one in chromosome segregation, and a second, independent function in cytokinesis through ZEN-4; AIR-2 and ZEN-4 may act in parallel to a second pathway that includes CYK-1; AIR-2 phosphorylates two adjacent, evolutionarily conserved C-terminal serines of the inner centromere protein ICP-1; AIR-2 forms a robust complex with CSC-1, BIR-1, and ICP-1; air-2 is expressed highly in embryos, in the mature oocytes, spermatocytes, and extruded polar bodies.
19	M03F8.6	M03F8.6	n/a	chrV 5,954,355	contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
20	pup-3	F59A3.9	n/a	chrI 5,532,199	pup-3 encodes a template-independent poly(U) polymerase with 3'' end RNA substrates, distantly similar to human ZCCHC6 and ZCCHC11; PUP-3 is paralogous to the GLD-2 family of poly(A) polymerases; PUP-3 has no obvious function in mass RNAi assays.
21	fkh-8	F40H3.4	n/a	chrII 6,190,440	fkh-8 encodes one of 15 C. elegans forkhead transcription factors; loss of fkh-8 activity via RNAi has been reported to result in either no defects or a weakly penetrant aldicarb resistance phenotype; an FKH-8 reporter fusion is expressed in nerve cells in the head and tail ganglia of both males and hermaphrodites with expression beginning in the later stages of embryogenesis and continuing through adulthood.
22	kal-1	K03D10.1	n/a	chrI 14,135,394	kal-1 encodes a cell surface protein that contains a WAP-type protease inhibitor domain and Type III fibronectin domains and is the C. elegans ortholog of human KAL-1, mutated in the X-linked form of the neurological disorder Kallmann syndrome; in C. elegans, both kal-1 loss-of-function mutations and kal-1 overexpression result in similar phenotypes that indicate KAL-1 activity is required for epithelial morphogenesis and axon branching; kal-1 transcriptional reporters reveal expression beginning in the 50-cell stage embryo in 2-3 cells with later embryonic expression in at least 8-10 AB-derived ventral neuroblasts that are a substrate for migrating epidermal cells during ventral enclosure; later expression in larvae and adults is restricted to anterior neurons, including AIY, AIZ, RID, M5, ASI, and labial sensory neurons, ventral nerve cord motorneurons, midbody neurons HSN, CAN, and PVM, tail neurons DVB, DVC, and PDB, and the nonneuronal excretory cell as well as in uterine muscles; in the AIY interneurons, kal-1 is part of a gene battery whose expression is under the control of the CEH-10 and TTX-3 Paired and LIM-type homeodomains, respectively.
23	nhr-198	K06B4.8	n/a	chrV 15,695,079	C. elegans NHR-198 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	srv-7	T22B7.5	n/a	chrX 5,643,888	C. elegans SRV-7 protein; contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
25	fbxb-25	F58E1.2	n/a	chrII 1,684,456	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
26	srg-1	C18F10.4	n/a	chrIII 6,257,730	C. elegans SRG-1 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
27	srx-73	F41F3.7	n/a	chrV 4,664,669	C. elegans SRX-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
28	F23C8.12	F23C8.12	n/a	chrI 2,451,478
29	K12H6.7	K12H6.7	n/a	chrII 2,835,833
30	lim-7	C04F1.3	n/a	chrI 5,721,019	lim-7 encodes a LIM homeodomain protein; a lim-7 mutation can result in lethality or sterility; lim-7 reporter fusion are specifically expressed in the somatic gonadal sheath cells during the L4 larval stage and continuing through adulthood.
31	F55C9.11	F55C9.11	n/a	chrV 19,307,376	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
32	C40A11.4	C40A11.4	n/a	chrII 2,138,139	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
33	ZC13.2	ZC13.2	n/a	chrX 881,854
34	grl-1	C24G6.7	n/a	chrV 5,532,342	grl-1 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; GRL-1 is expressed in intestine, neurons, and larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
35	Y51A2B.2	Y51A2B.2	n/a	chrV 18,375,467	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domain IPR006874 (Protein of unknown function DUF621)
36	taf-7.1	F54F7.1	n/a	chrX 11,836,759	The taf-7.1 gene encodes an ortholog of mammalian TATA-binding protein associated factor TAF7L (TAFIIQ, OMIM:300314) that in mice exhibits testis-specific expression; TAF-7 function in C. elegans is not yet known, as taf-7 inactivation by RNA interference does not result in any obvious developmental defects.
37	srb-7	F37C12.17	n/a	chrIII 7,178,120	C. elegans SRB-7 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
38	W04D2.5	W04D2.5	n/a	chrV 12,493,975	contains similarity to Pfam domain PF00411 Ribosomal protein S11 contains similarity to Interpro domain IPR001971 (Ribosomal protein S11)
39	srd-12	C39H7.6	n/a	chrIV 5,629,500	C. elegans SRD-12 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001073 (Complement C1q protein)
40	srh-62	ZK6.9	n/a	chrV 402,409	C. elegans SRH-62 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F47G4.6	F47G4.6	n/a	chrI 14,060,105	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)
42	W10D9.3	W10D9.3	n/a	chrII 458,256
43	R07C3.6	R07C3.6	n/a	chrII 924,524
44	R03A10.1	R03A10.1	n/a	chrX 15,430,484	contains similarity to Saccharomyces cerevisiae Protein involved in transcription-coupled repair nucleotide exicision repair of UV-induced DNA lesions; homolog of human CSB protein; SGD:YJR035W
45	Y56A3A.33	Y56A3A.33	n/a	chrIII 12,001,104	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
46	T20D4.19	T20D4.19	n/a	chrV 3,431,055	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
47	ver-2	T17A3.8	n/a	chrIII 148,578	C. elegans VER-2 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00569 (Zinc finger, ZZ type) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site), IPR000433 (Zinc finger, ZZ-type)
48	C43H6.3	C43H6.3	n/a	chrX 2,408,512	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
49	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
50	cfi-1	T23D8.8	n/a	chrI 9,997,318	cfi-1 encodes a DNA-binding protein containing an AT-rich interaction domain (ARID) that affects differentiation of the URA sensory neurons, AVD, and PVC interneurons; acts downstream of UNC-86 and LIN-32 in controlling URA and IL2 cell fate, and is expressed in some neurons and muscle cells.