UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R52.6	R52.6	2.0000000000000002e-66	chrII 2,112,662	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domains IPR003326 (Protein of unknown function DUF130), IPR001507 (Endoglin/CD105 antigen)
2	srh-239	T26H5.3	n/a	chrV 15,446,542	C. elegans SRH-239 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
3	F28D1.1	F28D1.1	n/a	chrIV 12,373,435	contains similarity to Pfam domains PF08149 (BING4CT (NUC141) domain) , PF00400 (WD domain, G-beta repeat) contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR012952 (BING4, C-terminal), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
4	F21D5.6	F21D5.6	n/a	chrIV 8,740,745	contains similarity to Xenopus laevis Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HIssubunit B).; SW:Q5HZP1
5	let-60	ZK792.6	n/a	chrIV 11,689,627	let-60 encodes a member of the GTP-binding RAS protooncogene family; let-60 activity is required for viability, vulval development, spicule development, germ line meiotic progression, posterior development of the hypodermis, chemotaxis, sex myoblast migration, and muscle membrane extension; let-60 acts genetically downstream of let-23 with respect to vulval development and upstream of the MAPK pathway with respect to chemotaxis; let-60 is expressed in neural, muscle, and hypodermal lineages.
6	C48B6.2	C48B6.2	n/a	chrI 6,917,161	contains similarity to Pfam domain PF01479 S4 domain contains similarity to Interpro domains IPR002942 (RNA-binding S4), IPR001912 (Ribosomal protein S4)
7	nhr-168	C50B6.8	n/a	chrV 13,332,476	C. elegans NHR-168 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	polq-1	W03A3.2	n/a	chrIII 5,797,057	C. elegans POLQ-1 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00476 (DNA polymerase family A) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR001098 (DNA-directed DNA polymerase, family A), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR002298 (DNA polymerase A), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
9	emb-27	F10B5.6	n/a	chrII 8,160,979	emb-27 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of the anaphase-promoting complex (APC) subunit APC-6 (CDC16); required maternally and paternally, EMB-27 activity is essential for proper execution of the metaphase-to-anaphase transition during meiosis (both oogenesis and spermatogenesis) and mitosis (during germline proliferation); EMB-27 activity is also critical for embryonic anterior-posterior (A-P) axis formation, production of the secreted eggshell, and normal vulval development; in establishing the embryonic A-P axis, EMB-27 likely acts upstream of the separin protease to ensure proper localization of PAR-3 and PAR-2 to the anterior and posterior cortices, respectively.
10	srx-38	C03A7.5	n/a	chrV 5,154,771	C. elegans SRX-38 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
11	spr-5	Y40B1B.6	n/a	chrI 13,443,987	spr-5 encodes the C. elegans ortholog of the human histone demethylase LSD1 (lysine-specific demethylase 1) that functions to mediate chromatin remodeling and transcriptional regulation; loss of spr-5 activity can suppress the egg-laying defective (Egl) phenotype of mutations in sel-12/presenilin and derepresses expression of hop-1, which encodes the second C. elegans presenilin, by 20- to 30-fold; in binding assays and yeast two-hybrid experiments, SPR-5 interacts with SPR-1, the C. elegans ortholog of CoREST.
12	R08D7.5	R08D7.5	n/a	chrIII 8,974,466	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
13	C56A3.5	C56A3.5	n/a	chrV 13,552,624	contains similarity to Ureaplasma parvum Hypothetical protein UU346.; TR:Q9PQE5
14	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	C36B7.4	C36B7.4	n/a	chrX 7,086,834
16	C05E7.4	C05E7.4	n/a	chrX 12,966,891	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
17	nhr-59	T27B7.1	n/a	chrV 2,277,137	C. elegans NHR-59 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	emb-30	F54C8.3	n/a	chrIII 9,438,172	emb-30 encodes an anaphase-promoting complex/cyclosome (APC/C) component orthologous to mammalian APC-4 and Schizosaccharomyces pombe Lid1; EMB-30 is required for the metaphase-to-anaphase transition during meiosis and mitosis, for establishing anterior-posterior polarity in the early embryo, and for proper localization of germline granules and the maternally provided PAR-2 and PAR-3 proteins.
19	ggr-3	F09C12.1	n/a	chrII 5,131,702	ggr-3 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels; expressed in the AVA, AVB, SMDD, DVA, SIAD, and in some other neurons of the nerve ring.
20	srz-94	F49H6.11	n/a	chrV 17,034,553	C. elegans SRZ-94 protein ;
21	fbxa-22	T12B5.5	n/a	chrIII 939,140	C. elegans FBXA-22 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
22	tag-313	Y66H1A.3	n/a	chrIV 444,376	C. elegans TAG-313 protein ; contains similarity to Bos taurus 39S ribosomal protein L55, mitochondrial precursor (L55mt) (MRP-L55).; SW:P0C2B8
23	C26D10.3	C26D10.3	n/a	chrII 8,327,460	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
24	F57G8.7	F57G8.7	n/a	chrV 16,329,811	contains similarity to Antarctic bacterium str 643 Metalloproteinase precursor.; TR:Q9KH34
25	nhr-177	F16B4.1	n/a	chrV 1,611,519	C. elegans NHR-177 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	W06B4.3	W06B4.3	n/a	chrII 4,464,653	contains similarity to Pfam domain PF05131 Pep3/Vps18/deep orange family contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR007810 (Pep3/Vps18/deep orange), IPR016024 (Armadillo-type fold)
27	C55C3.5	C55C3.5	n/a	chrIV 5,699,611	contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
28	gstk-2	D2024.7	n/a	chrIV 7,241,341	C. elegans GSTK-2 protein; contains similarity to Pfam domain PF01323 DSBA-like thioredoxin domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001853 (DSBA oxidoreductase), IPR014440 (HCCA isomerase/glutathione S-transferase kappa)
29	wrm-1	B0336.1	n/a	chrIII 5,724,932	wrm-1 encodes, along with bar-1 and hmp-2, one of three C. elegans beta-catenin-like proteins; during development, wrm-1 functions in noncanonical Wnt signaling pathways that specify cell fates in the early embryo, the somatic gonad, and postembryonic hypodermal lineages.
30	F54D11.3	F54D11.3	n/a	chrV 4,636,257
31	str-223	F49C5.6	n/a	chrII 12,564,977	C. elegans STR-223 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	K11H12.1	K11H12.1	n/a	chrIV 652,824	contains similarity to Pfam domain PF01722 BolA-like protein contains similarity to Interpro domain IPR002634 (BolA-like protein)
33	rheb-1	F54C8.5	n/a	chrIII 9,455,024	rheb-1 encodes a GTPase orthologous to the mammalian Rheb and Rheb1 GTPases; loss of rheb-1 activity via RNAi indicates that RHEB-1 is involved in the mitochondrial unfolded protein response and that its function is required for normal growth rates, body size, osmoregulation, reproduction, and locomotion.
34	B0432.9	B0432.9	n/a	chrII 283,160	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
35	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
36	cdc-48.3	K04G2.3	n/a	chrI 8,034,273	C. elegans CDC-48.3 protein; contains similarity to Pfam domains PF07726 (ATPase family associated with various cellular activities (AAA)) , PF00004 (ATPase family associated with various cellular activities (AAA)) , PF07728 (ATPase family associated with various cellular activities (AAA)) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR011704 (ATPase associated with various cellular activities, AAA-5), IPR011703 (ATPase associated with various cellular activities, AAA-3), IPR003960 (AAA ATPase, conserved site), IPR003593 (AAA+ ATPase, core)
37	mes-6	C09G4.5	n/a	chrIV 8,512,584	mes-6 encodes a WD repeat-containing protein that is orthologous to Drosophila Extra sex combs (Esc); as a member of a Polycomb-like chromatin repressive complex with MES-2 and MES-3, MES-6 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; MES-6 expression is detected in the nuclei of all cells during early embryogenesis, in the germline precursors Z2 and Z3 and faintly in some somatic cells during late embryogenesis and the L1 larval stage, widely in later larvae, and in germline and oocyte nuclei in adults; normal MES-6 distribution is dependent upon wild-type activity of MES-2 and MES-3, and likewise, distribution of MES-3 is dependent upon wild-type activity of MES-2 and MES-6
38	F21D5.8	F21D5.8	n/a	chrIV 8,739,792	contains similarity to Homo sapiens 13 kDa protein; ENSEMBL:ENSP00000376734
39	T09E11.1	T09E11.1	n/a	chrI 12,338,593	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
40	F58B3.7	F58B3.7	n/a	chrIV 11,639,167	contains similarity to Pfam domains PF01585 (G-patch domain) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR016967 (Splicing factor, SPF45), IPR003954 (RNA recognition, region 1), IPR000467 (D111/G-patch), IPR000504 (RNA recognition motif, RNP-1), IPR009145 (U2 auxiliary factor small subunit)
41	F53H4.3	F53H4.3	n/a	chrX 15,886,572	contains similarity to Mus musculus Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).; SW:ATX1_MOUSE
42	xbx-5	T24A11.2	n/a	chrIII 3,803,450	C. elegans XBX-5 protein ;
43	F09E5.9	F09E5.9	n/a	chrII 5,346,983
44	F01G10.10	F01G10.10	n/a	chrIV 10,247,944	contains similarity to Pfam domains PF02886 (LBP / BPI / CETP family, C-terminal domain) , PF01273 (LBP / BPI / CETP family, N-terminal domain) contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
45	hlh-19	F57C12.3	n/a	chrX 556,516	C. elegans HLH-19 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
46	C27F2.4	C27F2.4	n/a	chrIII 4,959,381	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
47	T20G5.9	T20G5.9	n/a	chrIII 10,210,308	contains similarity to Pfam domain PF09282 Mago binding contains similarity to Interpro domain IPR015362 (Exon junction complex, Pym)
48	H43I07.2	H43I07.2	n/a	chrV 4,201,565	contains similarity to Pfam domains PF01000 (RNA polymerase Rpb3/RpoA insert domain) , PF01193 (RNA polymerase Rpb3/Rpb11 dimerisation domain) contains similarity to Interpro domains IPR011263 (DNA-directed RNA polymerase, RpoA/D/Rpb3-type), IPR011262 (DNA-directed RNA polymerase, insert), IPR011261 (DNA-directed RNA polymerase, dimerisation)
49	C49A9.5	C49A9.5	n/a	chrIV 6,215,077	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
50	str-40	C50H11.12	n/a	chrV 3,068,667	C. elegans STR-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)