UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R12E2.14	R12E2.14	n/a	chrI 4,150,308	contains similarity to Interpro domain IPR004051 (Potassium channel, voltage dependent, Kv1.4)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
6	his-9	ZK131.3	n/a	chrII 13,823,762	his-9 encodes an H3 histone; by homology, HIS-9 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-9 is a replication-dependent histone locus that resides in the HIS3 cluster on chromosome II.
7	Y116A8B.4	Y116A8B.4	n/a	chrIV 17,224,339	contains similarity to Clostridium acetobutylicum Predicted membrane protein.; TR:Q97KC4
8	his-10	ZK131.4	n/a	chrII 13,823,128	his-10 encodes an H4 histone.
9	fbxb-40	M01D1.9	n/a	chrII 1,049,413	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
10	sri-1	F36G9.8	n/a	chrV 15,966,916	C. elegans SRI-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002208 (SecY protein)
11	T22C1.11	T22C1.11	n/a	chrI 7,967,828	contains similarity to Oryctolagus cuniculus Trichohyalin.; SW:P37709
12	his-56	F54E12.3	n/a	chrIV 11,338,648	his-56 encodes an H4 histone.
13	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	nac-2	R107.1	n/a	chrIII 9,040,048	nac-2 encodes a high affinity sodium-coupled citrate transporter that is orthologous to the mammalian citrate transporter NaCT and is one of four C. elegans proteins related to Drosophila Indy; when expressed in a heterologous system, NAC-2 exhibits high affinity sodium/citrate and sodium/succinate cotransporter activity, although the transport rate for citrate is much higher than that for succinate; nac-2::gfp reporter fusions are expressed in the intestine, from early larval stages through adulthood; the effects of nac-2(RNAi) are variable, with reports of a 19% increase in lifespan accompanied by decreased body size and fat content in affected animals and reports of no apparent decrease in average lifespan.
15	his-13	ZK131.7	n/a	chrII 13,820,324	his-13 encodes an H3 histone; his-13 is contained within the histone gene cluster HIS3.
16	fbxb-51	K05F6.3	n/a	chrII 1,552,094	C. elegans FBXB-51 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
17	daf-10	F23B2.4	n/a	chrIV 9,141,552	daf-10 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex A component IFT122; daf-10 activity is required for intraflagellar transport and thus for proper development of amphid and phasmid neurons, dauer development, chemotaxis, and normal lifespan; a DAF-10::GFP fusion protein undergoes both anterograde and retrograde intraflagellar transport in amphid or phasmid sensory neurons.
18	C03A7.12	C03A7.12	n/a	chrV 5,179,902	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
19	W04A8.3	W04A8.3	n/a	chrI 13,845,353	contains similarity to Plasmodium falciparum Reticulocyte-binding protein, putative.; TR:Q8I4R2
20	K08H2.2	K08H2.2	n/a	chrX 13,234,539	contains similarity to Homo sapiens Hypothetical protein KIAA0144; ENSEMBL:ENSP00000271877
21	srsx-18	C04E6.2	n/a	chrV 5,923,404	C. elegans SRSX-18 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
22	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
23	Y70D2A.1	Y70D2A.1	n/a	chrX 14,922,327	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR000276 (GPCR, rhodopsin-like)
24	ZC204.2	ZC204.2	n/a	chrII 1,664,783	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
25	F14H8.5	F14H8.5	n/a	chrV 15,021,516	contains similarity to Bacillus cereus Hypothetical membrane spanning protein.; TR:Q812W2
26	nhr-213	T06C12.13	n/a	chrV 15,895,604	C. elegans NHR-213 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
27	F27C1.4	F27C1.4	n/a	chrI 5,423,026
28	ZK218.7	ZK218.7	n/a	chrV 17,106,188	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR000480 (Glutelin), IPR003582 (Metridin-like ShK toxin)
29	R57.2	R57.2	n/a	chrX 298,212	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
30	T20D4.19	T20D4.19	n/a	chrV 3,431,055	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
31	T27A8.1	T27A8.1	n/a	chrX 16,052,166	T27A8.1 encodes a putative metallocarboxypeptidase orthologous to human AEBP1 (OMIM:602981) and carboxypeptidase D, E, M, N, X2, and Z precursors; T27A8.1 and its human orthologs, along with other proteins, comprise an M14B peptidase subfamily; T27A8.1 has no obvious function in mass RNAi assays.
32	K12B6.8	K12B6.8	n/a	chrV 6,310,389	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
33	mab-7	ZC13.4	n/a	chrX 895,155	mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically affecting the structural cells, neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab-7 promoter-gfp construct is expressed in hypodermis, body seam, ray structural cells, and several neurons in the head and tail region.
34	his-14	ZK131.8	n/a	chrII 13,819,690	his-14 encodes an H4 histone.
35	T28A11.18	T28A11.18	n/a	chrV 3,267,438	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
36	T21E12.2	T21E12.2	n/a	chrI 4,414,499	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
37	T28C6.8	T28C6.8	n/a	chrIV 8,830,136	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
38	ugt-24	C49A9.8	n/a	chrIV 6,208,144	C. elegans UGT-24 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
39	srg-37	K04C1.1	n/a	chrX 14,234,536	C. elegans SRG-37 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
40	F47H4.2	F47H4.2	n/a	chrV 17,356,736	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
41	scl-4	C39E9.1	n/a	chrIV 13,062,457	C. elegans SCL-4 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR000480 (Glutelin)
42	sdz-38	ZK892.7	n/a	chrII 9,981,301	C. elegans SDZ-38 protein; contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
43	his-2	T10C6.13	n/a	chrV 16,041,899	his-2 encodes an H3 histone; his-2 is contained within the histone gene cluster HIS1.
44	C14A6.8	C14A6.8	n/a	chrV 18,170,317	contains similarity to Gallus gallus Cellular tumor antigen p53 (Tumor suppressor p53).; SW:P53_CHICK
45	kin-29	F58H12.1	n/a	chrX 2,848,198	kin-29 encodes a serine/threonine kinase with significant homology in the kinase domain to the AMP-activated protein kinase (AMPK) and SNF1 kinases; the AMP-kinase cascade is activated by cellular stresses that deplete ATP; AMP-kinase is believed to protect the mammalian cell by 'switching off' ATP-consuming pathways like fatty acid synthesis, by phosphorylating key regulatory enzymes, and switching on alternative pathways for ATP generation; kin-29 is involved in regulating the expression of chemosensory receptors and entry into the daur pathway; kin-29 also affects body size via interaction with the Sma/Mab pathway and lifespan, with mutants exhibiting a smaller body size and increased life span; a functional KIN-29-GFP fusion protein is expressed in sensory neurons and many other cell types, and localizes to the cytoplasm; under conditions of cellular stress like heat shock and starvation, KIN-29-GFP translocates to the nucleus.
46	nhr-288	Y51A2B.3	n/a	chrV 18,381,620	C. elegans NHR-288 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
47	lips-4	K12B6.3	n/a	chrV 6,279,558	C. elegans LIPS-4 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
48	arl-6	C38D4.8	n/a	chrIII 4,814,024	arl-6 encodes an ADP-Ribosylation factor-Like member of the Ras superfamily of small GTP-binding proteins and is a predicted homolog of the human ARL6 gene, identified as the gene that underlies Bardet-Biedl syndrome type 3; GFP-tagged ARL-6 undergoes intraflagellar transport (IFT) in the ciliary axoneme, implicating ARL-6 in ciliary transport; arl-6 is expressed in amphid and phasmid ciliated sensory neurons.
49	C35A5.9	C35A5.9	n/a	chrV 10,527,324	C35A5.9 encodes a class 4 histone deacetylase (HDAC), orthologous to human HDAC11.
50	set-12	K09F5.5	n/a	chrX 7,734,685	set-12 encodes a putative histone H3 lysine-9 methyltransferase with no non-nematode orthologs; neither set-12(n4442) nor set-12(RNAi) have any obvious phenotypes.