UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	glb-22	R11H6.3	0	chrV 14,605,162	glb-22 encodes a globin with no obvious function in mass RNAi assays.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	srw-17	T10H4.6	n/a	chrV 15,276,192	C. elegans SRW-17 protein; contains similarity to Interpro domains IPR000190 (AT1 angiotensin II receptor), IPR017452 (GPCR, rhodopsin-like superfamily), IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter)
5	F22F1.2	F22F1.2	n/a	chrX 8,150,103	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
6	Y43F8B.6	Y43F8B.6	n/a	chrV 19,493,363	contains similarity to Yersinia pestis Putative insecticial toxin.; TR:Q8ZAV3
7	nhr-140	C33G8.9	n/a	chrV 6,988,762	C. elegans NHR-140 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	C54A12.2	C54A12.2	n/a	chrII 5,254,604	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
9	nhr-42	C33G8.6	n/a	chrV 6,999,694	C. elegans NHR-42 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	F31E8.1	F31E8.1	n/a	chrII 6,829,225
11	D1022.5	D1022.5	n/a	chrII 7,458,058
12	T22F7.4	T22F7.4	n/a	chrIII 526,147
13	twk-23	F19D8.1	n/a	chrX 13,819,543	twk-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-23 in C. elegans development and/or behavior is not yet known, however TWK-23 may function redundantly with other TWK channels; TWK-23 is expressed in neurons, muscle, the posterior intestine, and diffusely in many other tissues.
14	F47H4.2	F47H4.2	n/a	chrV 17,356,736	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
15	M01B2.6	M01B2.6	n/a	chrV 15,242,739	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
16	Y44A6D.3	Y44A6D.3	n/a	chrV 20,786,983	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
17	nhr-191	F55D12.3	n/a	chrI 7,896,919	C. elegans NHR-191 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	egl-38	C04G2.7	n/a	chrIV 10,108,695	The egl-38 gene encodes a Pax5 homolog.
19	F13H8.2	F13H8.2	n/a	chrII 6,272,139	contains similarity to Pfam domains PF04003 (Dip2/Utp12 Family) , PF00400 (WD domain, G-beta repeat) (8)contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR007148 (Small-subunit processome, Utp12), IPR015943 (WD40/YVTN repeat-like)
20	daf-10	F23B2.4	n/a	chrIV 9,141,552	daf-10 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex A component IFT122; daf-10 activity is required for intraflagellar transport and thus for proper development of amphid and phasmid neurons, dauer development, chemotaxis, and normal lifespan; a DAF-10::GFP fusion protein undergoes both anterograde and retrograde intraflagellar transport in amphid or phasmid sensory neurons.
21	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
22	C13A10.1	C13A10.1	n/a	chrII 1,353,185
23	clec-43	R07C3.1	n/a	chrII 945,103	C. elegans CLEC-43 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (3)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
24	str-183	T13F3.1	n/a	chrV 16,276,778	C. elegans STR-183 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	Y11D7A.10	Y11D7A.10	n/a	chrIV 9,259,330	contains similarity to Coniophora arida ATP synthase subunit 6 (EC 3.6.3.14) (ATP synthase A chain)s(Fragment).; TR:Q9XLN6
26	R03D7.2	R03D7.2	n/a	chrII 10,933,886	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
27	F25E2.3	F25E2.3	n/a	chrX 812,150	contains similarity to Pfam domain PF02551 Acyl-CoA thioesterase contains similarity to Interpro domain IPR003703 (Acyl-CoA thioesterase)
28	nhr-186	F47C10.3	n/a	chrV 3,853,607	C. elegans NHR-186 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
29	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	F35E8.9	F35E8.9	n/a	chrV 15,916,920	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
31	ttr-54	T14G10.4	n/a	chrIV 10,156,441	C. elegans TTR-54 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
32	srh-182	ZK228.5	n/a	chrV 18,472,715	C. elegans SRH-182 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	str-102	R08H2.13	n/a	chrV 15,385,819	C. elegans STR-102 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	T07C12.10	T07C12.10	n/a	chrV 9,960,139	contains similarity to Rattus norvegicus Trans-Golgi network integral membrane protein TGN38 precursor.; SW:TGN3_RAT
35	str-243	K02H11.7	n/a	chrV 1,523,505	C. elegans STR-243 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	try-4	F31D4.6	n/a	chrV 20,855,551	C. elegans TRY-4 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
37	lips-4	K12B6.3	n/a	chrV 6,279,558	C. elegans LIPS-4 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
38	srj-57	T03D3.14	n/a	chrV 2,854,982	C. elegans SRJ-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	C08B6.5	C08B6.5	n/a	chrV 10,118,697	contains similarity to Danio rerio Glutamate receptor delta-2 subunit precursor (GluR delta-2).; SW:Q68Y21
40	H25K10.2	H25K10.2	n/a	chrIV 16,210,717	contains similarity to Halobacterium sp ORF H0114.; TR:O51964
41	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
42	C31H5.1	C31H5.1	n/a	chrI 9,028,536	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative)
43	F08G2.8	F08G2.8	n/a	chrII 13,853,676	contains similarity to Triticum aestivum Alpha/beta-gliadin A-IV precursor (Prolamin).; SW:GDA4_WHEAT
44	F57C7.4	F57C7.4	n/a	chrX 10,585,230	contains similarity to Interpro domain IPR008972 ()
45	che-3	F18C12.1	n/a	chrI 8,071,859	The dynein heavy chain (DHC) 1b isoform that affects the establishment and maintainance of the structural integrity of sensory cilia and also has a role in intraflagellar transport; it is expressed in ciliated sensory neurons.
46	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
47	C54E10.2	C54E10.2	n/a	chrV 18,829,031	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
48	xtr-1	F54F7.4	n/a	chrX 11,852,038	xtr-1 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
49	abf-3	F54B8.5	n/a	chrV 15,817,602	abf-3 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-3 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
50	pde-5	C32E12.2	n/a	chrI 5,198,010	C. elegans PDE-5 protein; contains similarity to Pfam domains PF01590 (GAF domain) , PF00233 (3'5'-cyclic nucleotide phosphodiesterase) contains similarity to Interpro domains IPR002073 (3'5'-cyclic nucleotide phosphodiesterase), IPR003018 (GAF), IPR003607 (Metal-dependent phosphohydrolase, HD region)