UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R11F4.3	R11F4.3	0	chrII 4,071,458	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016054 (Ly-6 antigen / uPA receptor -like)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	T02G5.12	T02G5.12	n/a	chrII 7,097,415	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001411 (Tetracycline resistance protein, TetB), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
5	C14B1.6	C14B1.6	n/a	chrIII 3,716,084	contains similarity to Interpro domain IPR008162 (Inorganic pyrophosphatase)
6	D2096.11	D2096.11	n/a	chrIV 8,390,987	contains similarity to Pfam domains PF00307 (Calponin homology (CH) domain) (2), PF02187 (Growth-Arrest-Specific Protein 2 Domain) contains similarity to Interpro domains IPR003108 (Growth-arrest-specific protein 2), IPR002017 (Spectrin repeat), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding)
7	F08F8.2	F08F8.2	n/a	chrIII 7,360,724	contains similarity to Pfam domain PF00368 Hydroxymethylglutaryl-coenzyme A reductase contains similarity to Interpro domains IPR004554 (Hydroxymethylglutaryl-CoA reductase, class I, catalytic), IPR009029 (Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding), IPR002202 (Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)
8	F33H1.3	F33H1.3	n/a	chrII 10,173,524	contains similarity to Drosophila melanogaster Flybase gene name is CG2685-PA;; FLYBASE:CG2685
9	C47D12.2	C47D12.2	n/a	chrII 11,677,666	C47D12.2 encodes an ortholog of human FLJ20071/FLJ90130 (dymeclin, OMIM:607461, mutated in Dyggve-Melchior-Clausen dysplasia and Smith-McCort dysplasia), which has no obvious function in mass RNAi assays
10	F44A6.4	F44A6.4	n/a	chrX 10,214,952	contains similarity to Salmonella typhi Anaerobic sulfite reductase subunit A (EC 1.8.2.-).; TR:Q8Z4M7
11	nlp-24	F35B12.7	n/a	chrV 11,616,534	C. elegans NLP-24 protein; contains similarity to Interpro domain IPR000817 (Prion protein)
12	cdd-2	F49E8.4	n/a	chrIV 7,547,502	A functional cytidine deaminase that affects morphology of embryos; it is expressed at all life cycle stages.
13	C03H5.2	C03H5.2	n/a	chrII 390,779	C03H5.2 encodes a transporter of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc), orthologous to human SLC35A3 (OMIM:605632); CO3H5.2 is redundantly required, with its paralog SRF-3, for normal progression of oocytes through proximal gonads and for normal gonad morphology; C03H5.2 is expressed in many tissues, including pharynx, intestine, pharyngeal gland cells, seam cells, spermatheca, vulva, various muscles, hypodermis, and neurons; C03H5.2 transports both UDP-GlcNAc and UDP-GalNAc independently and simultaneously, with these two molecules neither competing with one another nor being transported as a heterodimer; C03H5.2's two transport activities are genetically separable, since an internally deleted version of C03H5.2 (lacking only 16 residues) retains normal levels of UDP-GlcNAc transport while losing 85-90% of its UDP-GalNAc transport activity; C03H5.2's activity has been experimentally validated through heterologous expression in budding yeast Golgi apparatus, and mutation of C03H5.2 in conserved residues greatly reduces this activity.
14	cpg-4	C10F3.1	n/a	chrV 5,997,803	cpg-4 encodes a large (782-residue), unfamiliar, putatively secreted protein with a C-terminal low-complexity domain; CPG-4 has 35 potential chondroitin attachment sites, mostly in its C-terminal half, 4 of which have been verified by mass spectrometry; CPG-4 has no obvious function in mass RNAi assays.
15	F41C3.1	F41C3.1	n/a	chrII 4,752,652	contains similarity to Pfam domain PF06887 Protein of unknown function (DUF1265) contains similarity to Interpro domain IPR009676 (Protein of unknown function DUF1265)
16	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
17	dbr-1	C55B7.8	n/a	chrI 6,491,723	dbr-1 encodes a homolog of the RNA lariat-debranching enzyme; DBR-1 is predicted to function in RNA processing by hydrolyzing the 2'-5' phosphodiester bond at the branchpoint of excised lariat intron RNA, thus converting the introns into linear molecules that can subsequently be degraded by exonucleases; in C. elegans, DBR-1 activity is required for embryonic and germline development, as well as for normal rates of postembryonic growth; overexpression of C. elegans DBR-1 in Saccharomyces cerevisiae can complement the RNA processing defects of a dbr1 null mutant strain, restoring debranching activity and intron degradation to near wild-type levels.
18	F26F4.5	F26F4.5	n/a	chrIII 4,889,536	contains similarity to Pfam domain PF00307 Calponin homology (CH) domain contains similarity to Interpro domains IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding)
19	F19C7.6	F19C7.6	n/a	chrIV 4,595,282
20	ugt-14	H23N18.2	n/a	chrV 4,907,256	C. elegans UGT-14 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
21	cyp-34A5	B0213.10	n/a	chrV 3,956,709	C. elegans CYP-34A5 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
22	M116.5	M116.5	n/a	chrIV 8,417,632	contains similarity to Pfam domains PF00307 (Calponin homology (CH) domain) (4), PF02187 (Growth-Arrest-Specific Protein 2 Domain) contains similarity to Interpro domains IPR003108 (Growth-arrest-specific protein 2), IPR002017 (Spectrin repeat), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding), IPR001589 (Actinin-type, actin-binding, conserved site)
23	str-81	T26H2.6	n/a	chrV 19,226,172	C. elegans STR-81 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	sna-2	T13F2.7	n/a	chrIV 9,776,092	sna-2 encodes an snRNP-binding protein (SNA-2/SL75p) homologous to Ascaris SL95p (SL 175kd); SNA-2 is found in at least two Sm snRNPs, SL1 and Y, but not in SL2; in snRNP SL1, SNA-2 associates with the SNA-1/SL21p protein, while associating with SUT-1/SL26p (a paralog of SNA-1) in snRNP Y; sna-2(RNAi) is lethal; SNA-2 can bind either SNA-1 or SUT-1 even in the absence of RNA.
25	K09B11.10	K09B11.10	n/a	chrIV 13,439,731	contains similarity to Interpro domain IPR000998 (MAM)
26	ZK507.6	ZK507.6	n/a	chrIII 9,107,905	contains similarity to Pfam domains PF00134 (Cyclin, N-terminal domain) , PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR004367 (Cyclin, C-terminal), IPR014400 (Cyclin, A/B/D/E)
27	F46C5.7	F46C5.7	n/a	chrII 8,839,705	contains similarity to Homo sapiens Splice isoform 1 of Q8WXQ8 Carboxypeptidase A5 precursor; ENSEMBL:ENSP00000289573
28	C06E1.7	C06E1.7	n/a	chrIII 8,592,089	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
29	srh-220	F47C12.5	n/a	chrIV 3,977,216	C. elegans SRH-220 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	D1043.1	D1043.1	n/a	chrII 11,585,601	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
31	srw-8	F59D6.5	n/a	chrV 3,033,490	C. elegans SRW-8 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
32	cash-1	K07C5.8	n/a	chrV 10,364,141	cash-1 encodes an ortholog of Drosophila CKA and the human striatins STRN, STRN3, and STRN4 that is required for vulval development; CASH-1 has an N-terminal region which may bind caveolin or calmodulin, and a C-terminal region with five tandem WD domains; by its orthology with CKA and striatins, CASH-1 is predicted to act as a scaffold linking signal transduction proteins (such as JKK-1 and JNK-1) to transcription factors (such as JUN-1 or FOS-1); CASH-1 is expressed broadly, in both larval and adult pharynx, intestine, rectal epithelium, hypodermis, and neurons, as well as the developing vulva and the adult reproductive system.
33	C29H12.5	C29H12.5	n/a	chrII 6,111,947	contains similarity to Pfam domain PF00385 'chromo' (CHRromatin Organisation MOdifier) domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR000953 (Chromo domain), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR016197 (Chromo domain-like)
34	coq-5	ZK652.9	n/a	chrIII 7,857,812	coq-5 encodes a putative 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, homologous to COQ5 in S. cerevisiae and to a family of methyltransferases involved in ubiquinone, menaquinone, biotin and sterol biosynthesis and in phosphatidylethanolamine methylation; COQ-5 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-5 can transgenically rescue a coq-5 deletion in S. cerevisiae; coq-5(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans.
35	T27A8.3	T27A8.3	n/a	chrX 16,062,905	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR011991 (Winged helix repressor DNA-binding)
36	cas-2	C18E3.6	n/a	chrI 4,191,639	C. elegans CAS-2 protein; contains similarity to Pfam domains PF01213 (Adenylate cyclase associated (CAP) N terminal) , PF08603 (DE Adenylate cyclase associated (CAP) C terminal) contains similarity to Interpro domains IPR001837 (Adenylate cyclase-associated CAP), IPR000694 (Proline-rich region), IPR013992 (Adenylate cyclase-associated CAP, N-terminal), IPR003073 (Orphan nuclear receptor, NURR type), IPR016098 (Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal), IPR006599 (CARP motif), IPR013912 (Adenylate cyclase-associated CAP, C-terminal)
37	F43H9.3	F43H9.3	n/a	chrV 8,024,072	contains similarity to Homo sapiens PAP associated domain containing 4; ENSEMBL:ENSP00000296783
38	ZC376.3	ZC376.3	n/a	chrV 14,169,887	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
39	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
40	htp-3	F57C9.5	n/a	chrI 4,828,421	C. elegans HTP-3 protein; contains similarity to Pfam domain PF02301 HORMA domain contains similarity to Interpro domain IPR003511 (DNA-binding HORMA)
41	T13B5.3	T13B5.3	n/a	chrII 1,099,395	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
42	K02D10.4	K02D10.4	n/a	chrIII 8,778,867
43	ZK1193.2	ZK1193.2	n/a	chrX 411,499	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR002049 (EGF-like, laminin), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans), IPR002035 (von Willebrand factor, type A)
44	6R55.2	6R55.2	n/a	chrX 17,713,765
45	R05D3.8	R05D3.8	n/a	chrIII 8,357,800	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
46	dcr-1	K12H4.8	n/a	chrIII 8,076,021	The dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III; dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs; DCR-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to DCR-1 for endonucleolytic processing.
47	clec-29	T25E12.9	n/a	chrV 16,738,407	C. elegans CLEC-29 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
48	ekl-1	F22D6.6	n/a	chrI 7,096,946	C. elegans EKL-1 protein; contains similarity to Pfam domain PF00567 Tudor domain contains similarity to Interpro domains IPR008191 (Maternal tudor protein), IPR002999 (Tudor)
49	R04B5.5	R04B5.5	n/a	chrV 10,088,214	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR011597 (GroES-related), IPR016040 (NAD(P)-binding), IPR002328 (Alcohol dehydrogenase, zinc-containing, conserved site)
50	tre-5	C23H3.7	n/a	chrII 54,158	C. elegans TRE-5 protein; contains similarity to Pfam domain PF01204 Trehalase contains similarity to Interpro domains IPR001661 (Glycoside hydrolase, family 37), IPR008928 (Six-hairpin glycosidase-like)