UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R10H10.4	R10H10.4	2e-41	chrIV 10,394,780	contains similarity to Arabidopsis thaliana T15B16.1 protein.; TR:Q9ZSH8
2	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
3	T07D10.1	T07D10.1	n/a	chrI 12,604,999	contains similarity to Strongylocentrotus purpuratus Katanin p80 subunit.; TR:O61585
4	F08H9.4	F08H9.4	n/a	chrV 14,463,959	F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
5	F47B10.8	F47B10.8	n/a	chrX 10,905,841	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
6	K02F6.5	K02F6.5	n/a	chrII 2,535,834	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
7	C55A1.7	C55A1.7	n/a	chrV 15,647,283	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
8	lgc-37	ZC482.5	n/a	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
9	srx-85	F38B7.4	n/a	chrV 11,553,428	C. elegans SRX-85 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
10	rab-28	Y11D7A.4	n/a	chrIV 9,243,090	rab-28 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; the precise biological role and expression pattern of rab-28 are not yet known.
11	C50E3.8	C50E3.8	n/a	chrV 7,598,180
12	F44A2.7	F44A2.7	n/a	chrV 9,322,227
13	srg-14	F26B1.6	n/a	chrI 6,313,673	C. elegans SRG-14 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
14	F36D4.4	F36D4.4	n/a	chrV 9,404,118	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000832 (GPCR, family 2, secretin-like), IPR000276 (GPCR, rhodopsin-like)
15	glb-27	W01C9.5	n/a	chrII 8,548,030	glb-27 encodes a globin whose expression is probably induced by anoxia in a HIF-1-dependent manner; glb-27 transcription is higher in L3 and dauers than in young adults; glb-27 has no obvious function in mass RNAi assays.
16	W03A5.1	W03A5.1	n/a	chrIII 5,410,601	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
17	nhr-167	C49F5.4	n/a	chrX 11,981,020	C. elegans NHR-167 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
19	gpc-1	K02A4.2	n/a	chrX 12,881,921	The gpc-1 gene encodes a heterotrimeric guanine nucleotide-binding protein gamma subunit, expressed specifically in sensory neurons, that is involved in taste adaptation.
20	F08F3.1	F08F3.1	n/a	chrV 5,447,387
21	T19D7.7	T19D7.7	n/a	chrX 678,427	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
22	H28G03.3	H28G03.3	n/a	chrX 5,221,191
23	aqp-6	C32C4.2	n/a	chrV 10,651,251	apq-6 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability five- to seven-fold; aqp-6 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-5; AQP-6 is expressed in the cilia and cell bodies of IL1 sensory neurons; AQP-6 is orthologous to human AQP8 (OMIM:603750).
24	F02H6.5	F02H6.5	n/a	chrIV 14,222,125	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR015904 (Sulphide quinone-reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
25	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
26	C18D1.2	C18D1.2	n/a	chrII 10,057,912	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
27	C15B12.3	C15B12.3	n/a	chrX 6,467,380
28	T23G4.2	T23G4.2	n/a	chrIV 13,688,527	contains similarity to Interpro domain IPR001984 (Peptidase S16, Lon protease)
29	F47F2.3	F47F2.3	n/a	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
30	F53B1.3	F53B1.3	n/a	chrX 2,106,394
31	sro-1	D1022.6	n/a	chrII 7,461,799	C. elegans SRO-1 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
32	F30B5.7	F30B5.7	n/a	chrIV 4,230,520	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
33	ZC239.3	ZC239.3	n/a	chrII 3,216,335	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
34	F42A9.9	F42A9.9	n/a	chrIV 8,638,434
35	C49G9.1	C49G9.1	n/a	chrI 12,565,152	contains similarity to Fugu rubripes Wilms tumour gene.; TR:O93433
36	C55A1.4	C55A1.4	n/a	chrV 15,642,939	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
37	T05B4.9	T05B4.9	n/a	chrV 4,117,993	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
38	T25B6.4	T25B6.4	n/a	chrX 9,016,157
39	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
40	F26A1.8	F26A1.8	n/a	chrIII 4,821,475	contains similarity to Interpro domain IPR000010 (Proteinase inhibitor I25, cystatin)
41	F40G9.6	F40G9.6	n/a	chrIII 179,840
42	ilys-4	C55F2.2	n/a	chrIV 7,896,569	C. elegans ILYS-4 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
43	C39D10.5	C39D10.5	n/a	chrX 7,891,348
44	F15G9.2	F15G9.2	n/a	chrX 9,713,365	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAW6
45	C55A1.6	C55A1.6	n/a	chrV 15,648,434	contains similarity to Lactococcus lactis Protein maturation protein.; TR:Q9CEV9
46	clec-264	F31D4.4	n/a	chrV 20,844,595	C. elegans CLEC-264 protein; contains similarity to Pfam domains PF01466 (Skp1 family, dimerisation domain) , PF03931 (Skp1 family, tetramerisation domain) contains similarity to Interpro domains IPR001232 (SKP1 component), IPR016072 (SKP1 component, dimerisation), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
47	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	C17H11.1	C17H11.1	n/a	chrX 8,177,329	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR000276 (GPCR, rhodopsin-like)
49	D2062.1	D2062.1	n/a	chrII 2,632,264	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
50	F49D11.2	F49D11.2	n/a	chrI 10,922,443	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)