UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srxa-10	R10E11.7	6e-173	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	inx-7	K02B2.4	n/a	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
4	F13A2.1	F13A2.1	n/a	chrV 4,381,556
5	H28G03.4	H28G03.4	n/a	chrX 5,223,420	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
6	F52E10.3	F52E10.3	n/a	chrX 16,283,853	contains similarity to Salmonella typhimurium Secretion system apparatus protein ssaM.; SW:SSAM_SALTY
7	C40H5.2	C40H5.2	n/a	chrX 11,754,976	contains similarity to Bifidobacterium longum Possible magnesium and cobalt transport protein.; TR:Q8G4E0
8	srx-42	C06B3.11	n/a	chrV 13,921,696	C. elegans SRX-42 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
9	T07D1.5	T07D1.5	n/a	chrX 2,419,146
10	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
11	T07D3.3	T07D3.3	n/a	chrII 895,627	contains similarity to Homo sapiens CGI16-iso; ENSEMBL:ENSP00000368599
12	D1037.1	D1037.1	n/a	chrI 3,687,476	contains similarity to Pfam domains PF00035 (Double-stranded RNA binding motif) , PF01585 (G-patch domain) contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR000694 (Proline-rich region), IPR014720 (Double-stranded RNA-binding-like), IPR000467 (D111/G-patch)
13	K10C2.6	K10C2.6	n/a	chrX 6,451,568
14	C47F8.3	C47F8.3	n/a	chrI 12,315,930	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
15	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
16	srx-8	C14C6.9	n/a	chrV 555,265	C. elegans SRX-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
17	C06B3.2	C06B3.2	n/a	chrV 13,901,062	contains similarity to Pfam domain PF00350 Dynamin family contains similarity to Interpro domain IPR001401 (Dynamin, GTPase region)
18	K04B12.3	K04B12.3	n/a	chrII 14,444,229	contains similarity to Anopheles gambiae str PEST AGAP010179-PA (Fragment).; TR:Q7Q0T1
19	F58B3.6	F58B3.6	n/a	chrIV 11,637,391	contains similarity to Pfam domains PF04836 (Interferon-related protein conserved region) , PF05004 (Interferon-related developmental regulator (IFRD)) contains similarity to Interpro domains IPR007701 (Interferon-related developmental regulator), IPR006921 (Interferon-related protein conserved region), IPR016024 (Armadillo-type fold)
20	T26G10.1	T26G10.1	n/a	chrIII 9,405,416	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
21	Y18D10A.1	Y18D10A.1	n/a	chrI 12,797,263	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding)
22	tbx-32	ZK380.1	n/a	chrX 1,656,225	C. elegans TBX-32 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
23	F08F8.4	F08F8.4	n/a	chrIII 7,358,292	contains similarity to Interpro domain IPR001126 (UMUC-like DNA-repair protein)
24	C11E4.7	C11E4.7	n/a	chrX 9,617,962
25	srt-1	C13B7.1	n/a	chrV 2,436,754	C. elegans SRT-1 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	C06C3.3	C06C3.3	n/a	chrII 9,370,697	contains similarity to Pfam domain PF03607 Doublecortin contains similarity to Interpro domain IPR003533 (Doublecortin)
27	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
28	grl-28	T24A6.15	n/a	chrV 3,551,603	grl-28 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
29	C32B5.6	C32B5.6	n/a	chrII 969,468
30	ZC196.4	ZC196.4	n/a	chrV 8,734,518	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR007883 (Protein of unknown function DUF713), IPR000565 (DNA topoisomerase, type IIA, subunit B)
31	ZC190.7	ZC190.7	n/a	chrV 8,686,461
32	ZK402.3	ZK402.3	n/a	chrX 1,402,534	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
33	H04M03.1	H04M03.1	n/a	chrIV 5,897,858	contains similarity to Pfam domain PF00821 Phosphoenolpyruvate carboxykinase contains similarity to Interpro domains IPR013035 (Phosphoenolpyruvate carboxykinase, C-terminal), IPR008210 (Phosphoenolpyruvate carboxykinase, N-terminal), IPR008209 (Phosphoenolpyruvate carboxykinase, GTP-utilising)
34	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
35	mig-17	F57B7.4	n/a	chrV 11,447,925	mig-17 encodes a secreted metalloprotease that is a member of the ADAM (A Disintegrin And Metalloprotease) protein family; MIG-17 activity is required for proper migration of gonadal leader cells, namely the hermaphrodite distal tip cells (DTCs) and the male linker cell (MLC); a MIG-17::GFP translational fusion protein is first detected in late embryos with expression continuing through adulthood; expression is initially seen on the pseudocoelomic face of body wall muscles and then on the surface of the gonad, when the DTCs migrate on the lateral hypodermis towards the dorsal muscles; proper MIG-17 localization and glycosylation requires activity of MIG-23, a membrane-bound nucleoside diphosphatase, as well as activity of COGC-3 and COGC-1, two members of the conserved oligomeric Golgi complex; expression studies with MIG-17 deletion derivatives indicate that MIG-17 is expressed by the body wall muscles and then localizes to the DTCs where its activity is sufficient for guiding DTC migration.
36	K10D11.2	K10D11.2	n/a	chrIV 12,980,447	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
37	F42C5.6	F42C5.6	n/a	chrIV 7,308,755
38	fem-2	T19C3.8	n/a	chrIII 633,323	A CB5161 ortholog of fem-2, Cbn-fem-2, has been isolated from the sibling Caenorhabditis species CB5161.
39	str-170	T08B6.7	n/a	chrIV 4,878,848	C. elegans STR-170 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	F48E8.4	F48E8.4	n/a	chrIII 5,456,244	contains similarity to Interpro domain IPR009011 (Mannose-6-phosphate receptor, binding)
41	C10C6.6	C10C6.6	n/a	chrIV 11,476,280	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
42	K06H6.5	K06H6.5	n/a	chrV 577,400	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
43	twk-4	ZK1067.5	n/a	chrII 9,192,128	C. elegans TWK-4 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
44	W07E6.3	W07E6.3	n/a	chrII 496,617	contains similarity to Interpro domain IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase)
45	C11D9.1	C11D9.1	n/a	chrI 4,424,085	contains similarity to Pfam domain PF00621 RhoGEF domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001478 (PDZ/DHR/GLGF)
46	K08F4.5	K08F4.5	n/a	chrIV 10,135,380	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
47	vha-1	R10E11.8	n/a	chrIII 9,781,407	vha-1 encodes an ortholog of subunit c of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-1 is a predicted V-ATPase transmembrane rotor component; VHA-1 and VHA-2/3 comprise a closely related family of subunit c co-orthologs, predicted to carry protons from the cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) for transmembrane export; VHA-1, like VHA-12 and VHA-17, antagonizes EFF-1-mediated cell fusion in hypodermal cells; VHA-1 is required for ovulation and embryogenesis, since vha-1(RNAi) animals are sterile with polyploid, unmatured oocytes and dead progeny; VHA-1 is required for alae formation, like the V0 subunits VHA-4 and VHA-5, but not like the V1 subunits VHA-8 or VHA-13; vha-1 shares an operon with vha-2 and R10E11.6; both vha-1 and vha-2 are expressed in the excretory cell, the rectum, and a pair of cells near the anus.
48	T21H3.5	T21H3.5	n/a	chrV 1,159,760
49	ilys-2	C45G7.2	n/a	chrIV 2,468,243	C. elegans ILYS-2 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
50	srg-61	C24B9.11	n/a	chrV 2,739,518	C. elegans SRG-61 protein; contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)