UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R102.1	R102.1	4e-74	chrIV 10,686,816	contains similarity to Oryza sativa Similar to Arabidopsis thaliana chromosome 4.; TR:Q9LWR6
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C01B4.8	C01B4.8	n/a	chrV 2,491,606	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
4	daf-5	W01G7.1	n/a	chrII 14,035,373	daf-5 encodes a proline-rich protein, conserved in C. briggsae but not observed in non-nematode genomes, that promotes dauer formation in the group II branch of the dauer pathway, may regulate chemosensation via AWC neurons, and may regulate egg laying; daf-5 mutations suppress the dauer phenotype of group II Daf-c mutants; daf-5(e1385) partially suppresses dauer formation by aex-6(sa699) mutants at 26.8 degrees C.
5	F41C6.6	F41C6.6	n/a	chrX 6,881,383
6	F28B1.1	F28B1.1	n/a	chrV 17,043,156	contains similarity to Mus musculus Hypothetical protein.; TR:Q8C3I4
7	E02C12.11	E02C12.11	n/a	chrV 9,379,644	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
8	ZK849.1	ZK849.1	n/a	chrI 14,184,199	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
9	myo-2	T18D3.4	n/a	chrX 12,471,624	myo-2 encodes a muscle-type specific myosin heavy chain isoform; myo-2 is expressed in pharyngeal muscle.
10	pqn-60	R11G11.7	n/a	chrV 504,306	pqn-60 encodes a 154-residue, glutamine/asparagine (Q/N)-rich ('prion'-like) protein, predicted to have coiled-coil structure, with many paralogs in nematodes but no obvious non-nematode orthologs; PQN-60 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
11	K01A6.4	K01A6.4	n/a	chrIV 11,739,659	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001419 (HMW glutenin)
12	F56D2.8	F56D2.8	n/a	chrIII 5,581,951
13	W09G12.6	W09G12.6	n/a	chrIV 1,232,354	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
14	T01H3.5	T01H3.5	n/a	chrII 7,880,026	T01H3.5 encodes an unfamiliar protein; T01H3.5 and T01H3.5 share an operon divergently transcribed from another operon containing vha-4.
15	unc-41	C27H6.1	n/a	chrV 9,971,233	unc-41 encodes an ortholog of Drosophila STONED A (STNA) required for normal locomotion; a beta-strand in the mu-adaptin-like domain of UNC-41 binds the C2A domain of SNT-1, and this binding is required for SNT-1 endocytosis, punctate localization of UNC-41 in neurons, and transgenic rescue of unc-41(e268) animals; UNC-41 is also required for normal secretion of EGL-17 from P6.p cells, and for embryonic viability; UNC-41 is expressed in the larval and adult nervous system; UNC-41, like other stonins, is an adaptin, and by orthology with stonins is predicted to be a protein adaptor that helps sort SNT-1 endocytotically.
16	myo-5	F58G4.1	n/a	chrV 8,113,539	C. elegans MYO-5 protein; contains similarity to Pfam domains PF01576 (Myosin tail) , PF00612 (IQ calmodulin-binding motif) , PF02736 (Myosin N-terminal SH3-like domain) , PF00063 (Myosin head (motor domain)) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin), IPR004009 (Myosin, N-terminal, SH3-like), IPR002928 (Myosin tail), IPR001609 (Myosin head, motor region)
17	snf-7	ZK1010.9	n/a	chrIII 13,008,187	C. elegans SNF-7 protein; contains similarity to Pfam domain PF00209 Sodium:neurotransmitter symporter family contains similarity to Interpro domain IPR000175 (Sodium:neurotransmitter symporter)
18	F58F9.6	F58F9.6	n/a	chrIV 6,236,744	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
19	K07F5.8	K07F5.8	n/a	chrIV 9,849,087	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
20	F37H8.3	F37H8.3	n/a	chrII 11,182,323	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR005834 (Haloacid dehalogenase-like hydrolase)
21	D1005.3	D1005.3	n/a	chrX 1,453,357	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
22	F46F5.4	F46F5.4	n/a	chrII 805,580	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
23	R05H10.1	R05H10.1	n/a	chrII 14,852,898	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
24	W01A8.3	W01A8.3	n/a	chrI 7,066,580	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
25	ace-1	W09B12.1	n/a	chrX 16,370,244	ace-1 encodes a class A acetylcholinesterase that functions redundantly with ACE-2 with respect to total class A acetylcholinesterase activity, and that genetically interacts with ace-2 and ace-3; ace-1 is expressed in the body wall muscle, sphincter muscle, head neurons, a few pharyngeal muscle cells, and the diagonal and spicule muscles of the male.
26	ins-26	ZC334.1	n/a	chrI 14,037,463	ins-26 encodes an insulin-like peptide.
27	ugt-43	F01D4.1	n/a	chrIV 10,466,113	C. elegans UGT-43 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
28	B0303.14	B0303.14	n/a	chrIII 8,714,993	contains similarity to Homo sapiens 33 kDa protein; VG:OTTHUMP00000025234
29	F16G10.2	F16G10.2	n/a	chrII 2,375,633	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
30	F35H12.1	F35H12.1	n/a	chrX 936,580	contains similarity to Interpro domain IPR015649 (Schwannomin interacting protein 1)
31	Y43F8C.15	Y43F8C.15	n/a	chrV 19,705,582
32	K01D12.3	K01D12.3	n/a	chrV 12,384,951	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
33	F40G9.14	F40G9.14	n/a	chrIII 176,962	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR007087 (Zinc finger, C2H2-type)
34	nhr-63	C06C6.4	n/a	chrV 16,003,610	C. elegans NHR-63 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
35	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
36	C16C8.17	C16C8.17	n/a	chrII 3,441,631	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domain IPR005098 (Protein of unknown function DUF281)
37	B0238.12	B0238.12	n/a	chrV 5,268,306	B0238.12 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; B0238.12 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; B0238.12 has no obvious function in mass RNAi assays.
38	arf-1.1	F45E4.1	n/a	chrIV 7,635,253	arf-1.1 encodes a member of the ADP-ribosylation factor family.
39	sfa-1	Y116A8C.32	n/a	chrIV 17,107,555	Y116A8C.32 encodes an ortholog of splicing factor SF1, which enables 3' splice site recognition by binding U2AF65 and the intron branch site during splicing complex formation; Y116A8C.32 shares several domains with mammalian SF1 proteins (a U2AF65 binding domain, a hnRNP K homology domain, two RNA-binding zinc knuckles, and a proline-rich C-terminal domain), while also sharing a hydrophilic N-terminal domain (enriched for serine, arginine, lysine, and aspartate) with Drosophila but not mammalian SF1; Y116A8C.32's N-terminal domain resembles RS domains in other splicing proteins; Y116A8C.32 is required for embryonic viability, normally rapid growth, and proper body morphology.
40	gst-40	F56B3.10	n/a	chrIV 761,476	C. elegans GST-40 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
41	clec-135	C16A11.8	n/a	chrII 4,257,930	C. elegans CLEC-135 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
42	T09B4.7	T09B4.7	n/a	chrI 6,160,874	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000104 (Antifreeze protein, type I), IPR000719 (Protein kinase, core)
43	ace-3	Y48B6A.8	n/a	chrII 14,207,809	ace-3 encodes one of four C. elegans acetylcholinesterases (AChE); ACE-3 represents ~5% of the total AChE activity in C. elegans and in vitro, hydrolyzes acetylthio-, butyrylthio-, and propionylthiocholine substrates with equal efficiency; although loss-of-function mutations in ace-3 result in no obvious defects, animals doubly mutant with ace-1 or ace-2 have slight defects in backward locomotion and animals triply mutant for ace-1, -2, and -3 arrest as unhatched, yet fully developed, embryos; ace-3 is the downstream gene in an operon with a fourth AChE-encoding gene, ace-4, and transcriptional reporter fusions with ace-4 upstream sequences direct expression in pharyngeal muscles pm3, 4, 5, and 7, the two CAN (canal associated neuron) cells, midbody dorsal body wall muscles in larvae, and several neurons in the head and anal ganglion
44	R13G10.4	R13G10.4	n/a	chrIII 3,827,770	R13G10.4 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, M02F4.3, and R04E5.2; by orthology with MAM3, R13G10.4 may participate in metal homoeostasis; R13G10.4, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; R13G10.4 is required for normal development in mass RNAi assays.
45	ZK1010.5	ZK1010.5	n/a	chrIII 12,985,882	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	Y23H5A.4	Y23H5A.4	n/a	chrI 2,618,955	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
47	cyp-33C8	R08F11.3	n/a	chrV 3,802,105	C. elegans CYP-33C8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
48	ZK1290.11	ZK1290.11	n/a	chrII 7,561,190
49	F16G10.5	F16G10.5	n/a	chrII 2,368,093
50	R13A5.9	R13A5.9	n/a	chrIII 7,577,267	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)