UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R09F10.3	R09F10.3	0	chrX 8,295,584	contains similarity to Dictyostelium discoideum Spore coat protein sp96.; SW:P14328
2	R07E5.3	R07E5.3	n/a	chrIII 4,405,506	The R07E5.3 gene encodes a homolog of SNF5/Ini1, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; R07E5.3 may be involved in asymmetric cell division of the T cells.
3	pix-1	K11E4.4	n/a	chrX 13,730,745	C. elegans PIX-1 protein ;
4	smo-1	K12C11.2	n/a	chrI 1,340,894	C. elegans SMO-1 protein; contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
5	cpf-2	F56A8.6	n/a	chrIII 13,267,824	C. elegans CPF-2 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
6	div-1	R01H10.1	n/a	chrIII 10,246,876	div-1 encodes a homolog of the B subunit of the DNA polymerase alpha-primase complex; DIV-1 is required in embryos for the normal timing of interphase in cell divisions, and for the asymmetric distribution of PIE-1 and P granules.
7	F33D11.10	F33D11.10	n/a	chrI 5,867,449	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
8	amx-1	R13G10.2	n/a	chrIII 3,824,311	C. elegans AMX-1 protein; contains similarity to Pfam domains PF01593 (Flavin containing amine oxidoreductase) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR001613 (Flavin-containing amine oxidase), IPR000960 (Flavin-containing monooxygenase FMO), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding), IPR007526 (SWIRM)
9	hst-2	C34F6.4	n/a	chrX 11,205,546	hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad.
10	taf-11.1	F48D6.1	n/a	chrX 4,255,964	C. elegans TAF-11.1 protein; contains similarity to Pfam domain PF04719 hTAFII28-like protein conserved region contains similarity to Interpro domains IPR006809 (TAFII28-like protein), IPR000104 (Antifreeze protein, type I), IPR009072 (Histone-fold)
11	ZK381.2	ZK381.2	n/a	chrIV 6,966,550	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
12	egl-18	F55A8.1	n/a	chrIV 1,915,415	egl-18 encodes a member of the GATA-family of transcription factors that affects cell migration, cell fate specification; expressed in the head, in hypodermal seam cells, VC neurons, and vulval precursor cells.
13	ugt-41	F10D2.11	n/a	chrV 7,162,312	C. elegans UGT-41 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
14	hil-6	F59A7.4	n/a	chrV 2,031,066	C. elegans HIL-6 protein; contains similarity to Pfam domain PF00538 linker histone H1 and H5 family contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR011991 (Winged helix repressor DNA-binding), IPR005819 (Histone H5), IPR003882 (Pistil-specific extensin-like protein), IPR005818 (Histone H1/H5), IPR003216 (Linker histone, N-terminal)
15	dao-3	K07E3.3	n/a	chrX 8,085,329	dao-3 encodes a protein containing tetrahydrofolate dehydrogenase/cyclohydrolase catalytic and NAD(P)-binding domains; by similarity to mammalian enzymes, DAO-3 is predicted to function in one-carbon unit metabolism and thus, in amino acid and nucleotide biosynthesis; dao-3 expression appears to be regulated by daf-2-mediated insulin signaling: microarray experiments suggest that it is upregulated in daf-2 mutant adults, while differential display and Northern analyses suggest that it is down-regulated; a dao-3 promoter gfp fusion is expressed in larvae in the hypodermis and in the nervous system, including tail neurons and phasmids.
16	F55A4.1	F55A4.1	n/a	chrX 1,036,270	contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR010908 (Longin), IPR011012 (Longin-like), IPR001388 (Synaptobrevin)
17	R03E9.2	R03E9.2	n/a	chrX 6,731,598	contains similarity to Interpro domain IPR001220 (Legume lectin, beta domain)
18	F26F12.4	F26F12.4	n/a	chrV 5,867,027
19	ZC250.3	ZC250.3	n/a	chrV 5,796,478	contains similarity to Pfam domain PF04142 Nucleotide-sugar transporter contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR007271 (Nucleotide-sugar transporter)
20	T10B5.3	T10B5.3	n/a	chrV 1,866,374	contains similarity to Pfam domain PF08162 NUC189 domain contains similarity to Interpro domain IPR012979 (Protein of unknown function NUC189, C-terminal)
21	R04A9.2	R04A9.2	n/a	chrX 374,567	contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
22	F53B1.6	F53B1.6	n/a	chrX 2,116,438	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR001279 (Beta-lactamase-like)
23	mig-2	C35C5.4	n/a	chrX 11,549,321	mig-2 encodes a member of the Rho family of GTP-binding proteins that affects the migration of Q neuroblasts, HSN cells, and CAN cells as well as axon outgrowth and guidance; it is expressed in early embryos and expressed in adults in the vulva, distal tip cells of the gonad, and the sex myoblasts and their descendants.
24	acbp-6	Y17G7B.1	n/a	chrII 11,972,918	C. elegans ACBP-6 protein; contains similarity to Pfam domain PF00887 Acyl CoA binding protein contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR000582 (Acyl-CoA-binding protein, ACBP)
25	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
26	F16D3.4	F16D3.4	n/a	chrI 8,366,932	F16D3.4 encodes a putative beta-tubulin folding cofactor D, orthologous to human TBCD (OMIM:604649); in early embryos, F16D3.4 is required for normally rapid microtubule elongation; F16D3.4 may be a ligand and effector of the ARL2 ortholog EVL-20; F16D3.4 is expressed in larval and adult pharynx, intestine, and neurons; in mass RNAi assays, F16D3.4 is required for normal mitotic spindle elongation, embryonic and larval viability, fertility, locomotion, body shape, vulval development, and cuticular integrity.
27	B0310.6	B0310.6	n/a	chrX 530,795
28	cdh-9	F59C12.1	n/a	chrX 16,598,558	cdh-9 encodes a member of the cadherin superfamily of transmembrane glycoproteins that mediate homophilic cell-cell adhesion; as loss of CDH-9 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CDH-9 in C. elegans development and/or behavior is not yet known.
29	sedl-1	W05H7.3	n/a	chrX 1,439,758	C. elegans SEDL-1 protein; contains similarity to Pfam domain PF04628 Sedlin, N-terminal conserved region contains similarity to Interpro domains IPR011012 (Longin-like), IPR006722 (Sedlin)
30	T19B10.9	T19B10.9	n/a	chrV 11,249,483	contains similarity to Interpro domain IPR000694 (Proline-rich region)
31	F19C6.3	F19C6.3	n/a	chrX 10,007,249	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF00093 (von Willebrand factor type C domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR008037 (Proteinase inhibitor I19, pacifastin), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR001007 (von Willebrand factor, type C)
32	his-2	T10C6.13	n/a	chrV 16,041,899	his-2 encodes an H3 histone; his-2 is contained within the histone gene cluster HIS1.
33	K04F10.7	K04F10.7	n/a	chrI 6,367,224	contains similarity to Homo sapiens Isoform 1 of Protein FAM76B; ENSEMBL:ENSP00000351631
34	F47G4.2	F47G4.2	n/a	chrI 14,080,352	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
35	F11E6.8	F11E6.8	n/a	chrIV 17,447,304	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
36	F14B4.1	F14B4.1	n/a	chrI 9,268,427	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) , PF00057 (Low-density lipoprotein receptor domain class A) , PF00058 (Low-density lipoprotein receptor repeat class B) (4)contains similarity to Interpro domains IPR000033 (), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding), IPR015943 (WD40/YVTN repeat-like)
37	cup-4	C02C2.3	n/a	chrIII 7,867,528	The primary phenotype of cup-4 animals is an accumulation of secreted GFP in the pseudocoelom, suggesting a decrease in, or the absence of, endocytosis in coelomocytes.
38	K08H10.9	K08H10.9	n/a	chrV 9,992,294	contains similarity to Pfam domain PF04051 Transport protein particle (TRAPP) component, Bet3 contains similarity to Interpro domain IPR007194 (Transport protein particle (TRAPP) component, Bet3)
39	F31E8.4	F31E8.4	n/a	chrII 6,799,569	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
40	C40H1.6	C40H1.6	n/a	chrIII 9,331,786	contains similarity to Pfam domain PF08694 Ubiquitin-fold modifier-conjugating enzyme 1 contains similarity to Interpro domains IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR014806 (Protein of unknown function DUF1782)
41	tra-4	F53B3.1	n/a	chrX 2,855,643	C. elegans TRA-4 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR008162 (Inorganic pyrophosphatase), IPR015880 (Zinc finger, C2H2-like), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
42	iftb-1	K04G2.1	n/a	chrI 8,027,270	iftb-1 encodes the C. elegans ortholog of translation initiation factor 2 beta (eIF2beta); by homology, IFTB-1 is predicted to function in translation initiation and start codon recognition; loss of iftb-1 via RNAi indicates that iftb-1 activity is required for a number of processes including growth, development, and body morphogenesis; loss of iftb-1 activity in adult animals extends lifespan.
43	tag-289	F14F3.3	n/a	chrX 10,523,120	C. elegans TAG-289 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
44	fbxb-57	F55C9.4	n/a	chrV 19,289,333	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
45	apm-3	F53H8.1	n/a	chrX 956,347	apm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.
46	snr-6	Y49E10.15	n/a	chrIII 12,429,334	snr-6 encodes the C. elegans ortholog of the small nuclear ribonucleoprotein E, one of seven subunits of the heptameric Sm complex required for the biogenesis and function of snRNPs that catalyze mRNA splicing; in addition to its predicted role in pre-mRNA processing, SNR-6 activity is essential for embryogenesis and is required for several aspects of germ cell specification including cell division patterns, localization and subcellular distribution of P granules, maintenance of transcriptional quiescence, and expression of the germ lineage-specific proteins PIE-1, GLD-1, and NOS-2; snr-6 is also required for wild-type levels of fertility; immunostaining of adults and embryos using antibodies raised against mammalian Sm proteins suggests that SNR-6 localizes to the nucleus and cytoplasm in many cell types, as well as to P granules in germ cells and their embryonic precursors.
47	R11E3.2	R11E3.2	n/a	chrIV 4,773,617	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
48	F17A9.4	F17A9.4	n/a	chrV 6,109,818	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal), IPR002343 (Paraneoplastic encephalomyelitis antigen)
49	D2023.5	D2023.5	n/a	chrV 11,826,462	contains similarity to Interpro domain IPR001763 (Rhodanese-like)
50	rnp-7	K04G7.10	n/a	chrIII 7,160,025	C. elegans RNP-7 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)