UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R09A1.3	R09A1.3	1e-180	chrV 1,025,455
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	rnp-1	ZK863.7	n/a	chrV 12,193,297	C. elegans RNP-1 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1), IPR001878 (Zinc finger, CCHC-type)
4	K06H7.2	K06H7.2	n/a	chrIII 8,094,871	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
5	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
6	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
7	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
8	Y38F1A.4	Y38F1A.4	n/a	chrII 12,967,952	contains similarity to Mus musculus Neuropeptide Y receptor type 6 (NPY6-R) (Pancreatic polypeptidesreceptor 2) (PP2).; SW:NY6R_MOUSE
9	K03H4.1	K03H4.1	n/a	chrV 13,151,458	contains similarity to Helicobacter pylori Transposase OrfB.; TR:Q93C83
10	C23H5.7	C23H5.7	n/a	chrIV 2,107,829	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000595 (Cyclic nucleotide-binding), IPR014710 (RmlC-like jelly roll fold)
11	cwn-2	W01B6.1	n/a	chrIV 10,069,006	cwn-2 encodes a member of the WNT family; expressed at highest levels in embryos and expression declines and is almost absent by the third larval stage.
12	vps-32.2	C37C3.3	n/a	chrV 7,850,487	C. elegans VPS-32.2 protein; contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
13	dpy-28	Y39A1B.3	n/a	chrIII 10,770,127	dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1.
14	T04C9.3	T04C9.3	n/a	chrIII 5,985,695
15	Y39A3A.3	Y39A3A.3	n/a	chrIII 2,067,514	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
16	C16D9.4	C16D9.4	n/a	chrV 8,241,945	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domains IPR008068 (Cytochrome P450, E-class, group I, CYP2B-like), IPR012444 (Protein of unknown function DUF1647)
17	K05C4.10	K05C4.10	n/a	chrI 14,725,700	contains similarity to Enterococcus faecalis Hypothetical protein.; TR:Q836A3
18	C47D12.8	C47D12.8	n/a	chrII 11,700,677	C47D12.8 encodes an ortholog of the DNA repair protein XPF/ERCC4, which when mutated in humans leads to xeroderma pigmentosum (complementation group F; OMIM:133520); C47D12.8(RNAi) animals are hypersensitive to ultraviolet radiation, with increased germ cell apoptosis and embryonic lethality; C47D12.8 protein interacts with F10G8.7 (an ERCC1 ortholog) in yeast two-hybrid assays; C47D12.8 is expressed broadly in both embryonic and postembryonic animals, and is required for embryonic development; C47D12.8 is upregulated in dauers, and shares an operon with kel-1 and VF13D12L.3.
19	F53C3.8	F53C3.8	n/a	chrII 3,891,751
20	T20G5.4	T20G5.4	n/a	chrIII 10,213,504	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
21	dpr-1	R10D12.2	n/a	chrV 13,941,139	dpr-1 encodes a putative nuclear hormone receptor that affects endoderm differentiation and may promote entry into the dauer state and maintenance of the dauer state; expressed in the endoderm lineage and localization appears dependent on growth conditions.
22	F18F11.4	F18F11.4	n/a	chrIV 332,622	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
23	nhr-215	T07C5.4	n/a	chrX 12,699,419	C. elegans NHR-215 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	sru-22	F36G9.5	n/a	chrV 15,973,922	C. elegans SRU-22 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
25	str-144	C09H5.5	n/a	chrV 8,071,381	C. elegans STR-144 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	fbxa-102	K03D7.7	n/a	chrV 17,492,710	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
27	osm-9	B0212.5	n/a	chrIV 3,554,256	The osm-9 gene encodes a capsaicin receptor homolog involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts.
28	F07C6.3	F07C6.3	n/a	chrIV 12,789,701	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
29	Y17D7C.1	Y17D7C.1	n/a	chrV 18,709,792	contains similarity to Trypanosoma brucei Hypothetical protein.; TR:Q7YVJ9
30	str-68	Y73C8C.6	n/a	chrV 3,106,888	C. elegans STR-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	K04H4.5	K04H4.5	n/a	chrIII 9,360,700	contains similarity to Yaba monkey tumor virus Yb-L1L protein.; TR:Q9QBC3
32	R07B1.6	R07B1.6	n/a	chrX 9,867,228	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
33	ZC482.3	ZC482.3	n/a	chrIII 12,762,606	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
34	T21D11.1	T21D11.1	n/a	chrIII 7,246,672	contains similarity to Pfam domain PF00413 Matrixin contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin)
35	nhr-83	F48G7.3	n/a	chrV 632,120	C. elegans NHR-83 protein; contains similarity to Pfam domains PF07914 (Protein of unknown function (DUF1679)) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR015897 (CHK kinase-like)
36	C28G1.2	C28G1.2	n/a	chrX 8,837,092	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
37	lrx-1	T04H1.6	n/a	chrV 12,253,997	lrx-1 encodes a protein that contains four class A low-density lipoprotein receptor domains.
38	srz-14	K05D4.3	n/a	chrV 16,184,163	C. elegans SRZ-14 protein ;
39	gpa-5	F53B1.7	n/a	chrX 2,119,972	gpa-5 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in AWA, with faint expression in ASI.
40	bcc-1	M7.3	n/a	chrIV 11,089,293	bcc-1 encodes a homolog of Drosophila and vertebrate Bicaudal C (BICC) that contains KH RNA-binding domains, a serine-rich region, and a SAM (sterile alpha motif) domain; by homology, BCC-1 is predicted to function as a cytoplasmic RNA-binding protein that is required for translational regulation and/or mRNA stability during embryonic or germline development; however, as loss of bcc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of BCC-1 in C. elegans development and/or behavior is not yet known.
41	mom-1	T07H6.2	n/a	chrX 6,295,619	mom-1 encodes a predicted O-acyltransferase that is orthologous to Porcupine proteins conserved across a wide range of species; MOM-1 functions as part of a Wnt/MAPK signaling pathway that is required maternally for endoderm induction in the early embryo; by homology, MOM-1 is predicted to be a membrane-spanning endoplasmic reticulum protein that stimulates post-translational processing of Wnt signaling molecules such as MOM-2; embryonic mosaic analysis indicates that MOM-1 activity is required in the signaling cell, P2, for proper specification of endoderm, consistent with its predicted role in processing MOM-2/Wnt.
42	C01G6.9	C01G6.9	n/a	chrII 9,294,851	contains similarity to Plasmodium falciparum SET-domain protein, putative.; TR:Q8IC77
43	nhr-54	F36D3.2	n/a	chrV 16,504,904	C. elegans NHR-54 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	sri-11	T22H2.3	n/a	chrI 11,696,802	C. elegans SRI-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
45	E02H9.1	E02H9.1	n/a	chrIII 2,468,952
46	C09F5.1	C09F5.1	n/a	chrIII 660,714
47	R12E2.6	R12E2.6	n/a	chrI 4,151,478	contains similarity to Interpro domain IPR000694 (Proline-rich region)
48	rhgf-1	F13E6.6	n/a	chrX 10,704,787	rhgf-1 encodes an RGS RhoGEF (Regulator of G-protein Signaling Rho Guanine Nucleotide Exchange Factor); RHGF-1 functions within cholingergic motor neurons in one of four G-protein-mediated signaling pathways that control locomotion via regulation of acetylcholine (ACh) release at neuromuscular junctions; in regulating ACh release, RHGF-1 functions downstream of the C. elegans Galpha12 ortholog, GPA-12, and upstream of the Rho GTPase ortholog, RHO-1; additionally, rhgf-1 activity is required for normal mechanosensory behavior, egg laying, and embryonic development; an rhgf-1 reporter fusion is expressed in ventral cord motor neurons as well as several head neurons.
49	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
50	srw-108	R11G11.5	n/a	chrV 528,386	C. elegans SRW-108 protein ;