UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R07H5.10	R07H5.10	4e-173	chrIV 11,214,469	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
5	F41E6.1	F41E6.1	n/a	chrV 8,624,595
6	ZC132.5	ZC132.5	n/a	chrV 4,306,648	contains similarity to Pfam domain PF05380 Pao retrotransposon peptidase contains similarity to Interpro domains IPR008042 (Retrotransposon, Pao), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
7	F47G6.2	F47G6.2	n/a	chrI 1,475,611	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
8	D1007.3	D1007.3	n/a	chrI 4,576,495
9	clec-156	F26A1.11	n/a	chrIII 4,842,010	C. elegans CLEC-156 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	lge-1	K09C8.4	n/a	chrX 10,968,138	C. elegans LGE-1 protein; contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
11	cyp-34A10	B0213.16	n/a	chrV 3,971,866	C. elegans CYP-34A10 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
12	srh-115	Y61B8A.2	n/a	chrV 17,256,442	C. elegans SRH-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	R10D12.8	R10D12.8	n/a	chrV 13,951,956	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
14	M04D8.5	M04D8.5	n/a	chrIII 10,032,724	contains similarity to Periplaneta americana Large conductance calcium activated potassium channel pSlo spliceforms1-5A.; TR:Q8I9V1
15	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
16	srz-1	F14F8.3	n/a	chrV 16,676,674	srz-1 encodes a predicted seven-pass G protein-coupled receptor; as loss of srz-1 activity via large-scale RNAi screens results in no obvious abnormalities, the precise role of SRZ-1 in C. elegans development and/or behavior is not yet known.
17	ZC416.4	ZC416.4	n/a	chrIV 3,607,952	n/a
18	ZK688.7	ZK688.7	n/a	chrIII 7,911,165
19	F02D8.1	F02D8.1	n/a	chrV 14,975,819	contains similarity to Rattus norvegicus P27 KIP1.; TR:O08769
20	nhr-169	C54C8.1	n/a	chrI 12,443,002	C. elegans NHR-169 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	F40G12.2	F40G12.2	n/a	chrV 14,260,215	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
22	fbxa-188	F47H4.8	n/a	chrV 17,343,887	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
23	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
24	T12B3.4	T12B3.4	n/a	chrIV 7,386,993	contains similarity to Pfam domain PF03637 Mob1/phocein family contains similarity to Interpro domain IPR005301 (Mob1/phocein)
25	fbxa-213	Y37H2C.3	n/a	chrV 18,268,033	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
26	F18A12.6	F18A12.6	n/a	chrII 3,401,335	F18A12.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.6 has no clear orthologs in other organisms.
27	C56G7.3	C56G7.3	n/a	chrIII 3,391,206	contains similarity to Pfam domain PF04727 ELMO/CED-12 family contains similarity to Interpro domain IPR006816 (Engulfment and cell motility, ELM)
28	srt-67	B0238.5	n/a	chrV 5,256,766	C. elegans SRT-67 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
29	srw-66	Y57G7A.4	n/a	chrII 1,270,733	C. elegans SRW-66 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	T19D2.3	T19D2.3	n/a	chrX 3,939,726
31	Y51A2A.6	Y51A2A.6	n/a	chrV 18,303,075	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
32	fbxa-30	ZC47.4	n/a	chrIII 1,275,041	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	R06F6.6	R06F6.6	n/a	chrII 10,807,531	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
34	F55F1.1	F55F1.1	n/a	chrX 2,779,060	contains similarity to Homo sapiens Rho family guanine-nucleotide exchange factor; ENSEMBL:ENSP00000328118
35	K03A11.4	K03A11.4	n/a	chrX 13,080,030	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
36	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
37	C45G9.8	C45G9.8	n/a	chrIII 5,052,953
38	srd-31	F07C4.8	n/a	chrV 7,634,059	C. elegans SRD-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	Y57G7A.1	Y57G7A.1	n/a	chrII 1,299,102
40	F59H6.2	F59H6.2	n/a	chrII 2,021,048
41	str-96	T10H4.2	n/a	chrV 15,293,203	C. elegans STR-96 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	K09F5.1	K09F5.1	n/a	chrX 7,740,721
43	B0041.1	B0041.1	n/a	chrI 4,665,314
44	F37C4.2	F37C4.2	n/a	chrIV 3,887,244	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
45	egl-23	Y37A1B.11	n/a	chrIV 14,007,827	egl-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; egl-23 was originally defined by gain-of-function mutations that result in defects in locomotion, egg-laying, and enteric muscle activation; loss of egl-23 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that EGL-23 may function redundantly with other TWK channels; egl-23 does not, however, interact genetically with the UNC-93 group of TWKs encoded by unc-93, sup-9, and sup-10; the EGL-23 expression pattern is not yet known.
46	K08C9.6	K08C9.6	n/a	chrI 11,499,274	contains similarity to Archaeoglobus fulgidus Hypothetical protein AF0327.; TR:O29920
47	F37C4.1	F37C4.1	n/a	chrIV 3,890,907	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
48	stdh-1	C06B3.4	n/a	chrV 13,907,215	stdh-1 encodes a putative steroid dehydrogenase required for normally short lifespan; STDH-1 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-2/-4; STDH-1 is expressed in larval intestine, and in both larval and adult body wall muscle and neurons.
49	E03H4.12	E03H4.12	n/a	chrI 12,436,494	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
50	C18F10.2	C18F10.2	n/a	chrIII 6,274,532	contains similarity to Schizosaccharomyces pombe Sporulation-specific protein 15.; SW:Q10411