UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R07G3.6	R07G3.6	6.9999999999999996e-161	chrII 7,604,709	contains similarity to Interpro domain IPR000694 (Proline-rich region)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
4	F01G10.6	F01G10.6	n/a	chrIV 10,226,957	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
5	sym-5	C44H4.2	n/a	chrX 14,579,420	sym-5 encodes a predicted transmembrane protein that contains 13 contiguous leucine-rich repeats (LRRs) and that is similar to SYM-1, a secreted protein involved in muscle attachment; sym-5 activity appears to be required for embryogenesis and functionally overlaps with that of sym-1 and mec-8 in affecting muscle attachment; in addition, loss of sym-5 activity via RNA-mediated interference (RNAi) in a hypersensitized strain indicates that SYM-5 may also be required for locomotion, body morphology, and normal rates of postembryonic growth.
6	col-17	F11G11.10	n/a	chrII 4,866,996	col-17 encodes a collagen which is expressed in all developmental stages except eggs, like col-15, col-16, and col-20; collagen genes with this expression pattern may be used for synthesis of cuticles after the L1 stage (e.g., the L4 cuticle).
7	C14F11.6	C14F11.6	n/a	chrX 6,238,566	contains similarity to Pfam domain PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase contains similarity to Interpro domains IPR000888 (dTDP-4-dehydrorhamnose 3,5-epimerase related), IPR011051 (Cupin, RmlC-type), IPR014710 (RmlC-like jelly roll fold)
8	ptr-4	C45B2.7	n/a	chrX 6,063,339	ptr-4 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-4 is strongly required for normal molting from L4 to adult stages male tail development (a role conserved in C. briggsae); PTR-4 is also required for normal endocytosis of yolk by oocytes, adult alae formation, growth to full size, locomotion, and viability.
9	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
10	F25D1.3	F25D1.3	n/a	chrV 10,529,632	contains similarity to Pfam domain PF06083 Interleukin-17 contains similarity to Interpro domain IPR010345 (Interleukin-17)
11	R05A10.6	R05A10.6	n/a	chrIV 14,167,109	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
12	col-128	F12F6.9	n/a	chrIV 11,550,954	C. elegans COL-128 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
13	F58H10.1	F58H10.1	n/a	chrI 7,756,062	contains similarity to Homo sapiens Splice isoform Long of Q8WXX7 Autism susceptibility gene 2 protein; ENSEMBL:ENSP00000329863
14	F13B9.2	F13B9.2	n/a	chrX 8,286,170
15	ptr-15	T07H8.6	n/a	chrV 6,968,181	ptr-15 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-15 has no known function in vivo.
16	F52F10.2	F52F10.2	n/a	chrV 1,549,423	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
17	F07E5.7	F07E5.7	n/a	chrII 2,071,109	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
18	M153.1	M153.1	n/a	chrX 12,147,684	contains similarity to Pfam domains PF03807 (NADP oxidoreductase coenzyme F420-dependent) , PF01210 (NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus) contains similarity to Interpro domains IPR004455 (NADP oxidoreductase, coenzyme F420-dependent), IPR000304 (Delta 1-pyrroline-5-carboxylate reductase), IPR011128 (NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal), IPR016040 (NAD(P)-binding)
19	C06A6.5	C06A6.5	n/a	chrIV 7,833,492	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
20	C13C12.2	C13C12.2	n/a	chrV 12,524,627	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
21	wrt-2	F52E4.6	n/a	chrX 3,093,375	wrt-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of low-complexity sequence; WRT-2 is expressed in seam cells and hypodermal syncytia; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-2 is weakly required for normal molting; WRT-2 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking; in two-hybrid assays, WRT-2 binds EYA-1, which may parallel the derepression of Drosophila eyes absent by HEDGEHOG.
22	W04G3.1	W04G3.1	n/a	chrX 11,060,857	contains similarity to Interpro domain IPR011038 (Calycin-like)
23	T13F2.4	T13F2.4	n/a	chrIV 9,790,151	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IIE7
24	F18C5.5	F18C5.5	n/a	chrII 6,566,049	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR002373 (cAMP/cGMP-dependent protein kinase)
25	T19B10.5	T19B10.5	n/a	chrV 11,235,863	T19B10.5 encodes a protein with partial similarity to human PERIAXIN (PRX; OMIM:605725), which when mutated leads to Dejerine-Sottas neuropathy.
26	T14B4.5	T14B4.5	n/a	chrII 6,717,303
27	T09F3.1	T09F3.1	n/a	chrII 10,386,641	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
28	F54B11.11	F54B11.11	n/a	chrX 13,580,176	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
29	F19H8.2	F19H8.2	n/a	chrII 14,604,795	contains similarity to Saccharomyces cerevisiae Transcriptional activator of lysine pathway genes with 2-aminoadipate semialdehyde as co-inducer; saccharopine reductase synthesis; SGD:YDR034C
30	T14D7.2	T14D7.2	n/a	chrII 8,850,480	T14D7.2 encodes an acyltransferase; large-scale RNAi experiments indicate that T14D7.2 activity is required for egg laying, coordination locomotion, and normal vulval morphology.
31	phg-1	F27E5.4	n/a	chrII 10,138,351	C. elegans PHG-1 protein; contains similarity to Pfam domain PF02351 GDNF/GAS1 domain contains similarity to Interpro domain IPR016017 (GDNF/GAS1)
32	K09B3.1	K09B3.1	n/a	chrIV 3,795,512	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
33	cpt-6	W01A11.5	n/a	chrV 6,491,977	C. elegans CPT-6 protein; contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
34	Y38H6C.16	Y38H6C.16	n/a	chrV 20,532,568	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
35	C17F4.2	C17F4.2	n/a	chrII 3,249,035
36	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
37	C38C6.3	C38C6.3	n/a	chrII 14,633,822	contains similarity to Schizosaccharomyces pombe Hypothetical transmembrane protein.; TR:O74525
38	zbed-6	F25H8.6	n/a	chrIV 9,919,215	zbed-6 encodes a protein that contains a BED-type zinc finger domain; loss of zbed-6 activity in large-scale RNAi screens indicates that zbed-6 is required for larval development.
39	F35D2.2	F35D2.2	n/a	chrII 7,575,045
40	R07E3.6	R07E3.6	n/a	chrX 10,319,714	contains similarity to Interpro domain IPR000694 (Proline-rich region)
41	F49E11.2	F49E11.2	n/a	chrIV 13,037,470	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
42	F59B10.5	F59B10.5	n/a	chrII 10,522,410	contains similarity to Encephalitozoon cuniculi Hypothetical protein ECU03_0100.; TR:Q8SW77
43	C50D2.1	C50D2.1	n/a	chrII 113,049
44	F56D5.6	F56D5.6	n/a	chrIV 9,407,298	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
45	T16G1.2	T16G1.2	n/a	chrV 12,931,137	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	ztf-2	F13G3.1	n/a	chrI 7,292,255	C. elegans ZTF-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR013993 (Zinc finger, N-recognin, metazoa), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
47	mec-5	E03G2.3	n/a	chrX 15,946,401	mec-5 encodes a collagen unique in the number of Gly-X-Y repeats and in the composition of amino acids surrounding these repeats; MEC-5 is required for normal mechanosensory response to gentle touch and for the proper functioning of the touch receptor neurons; mec-5 interacts genetically with mec-4 and mec-10 which encode degenerins (ion channels) expressed in the touch neurons, mec-9, which encodes a protein containing EGF-like and Kunitz/protease inhibitor domains secreted by the touch neurons, and mec-12, which encodes an alpha-tubulin expressed in the touch neurons; these genetic interactions suggest that MEC-5 may play a role in anchoring the degenerin complex to the extracellular matrix; MEC-5 is produced and secreted by hypodermal cells.
48	prl-1	T19D2.2	n/a	chrX 3,941,707	C. elegans PRL-1 protein; contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
49	ZC328.1	ZC328.1	n/a	chrI 6,405,136
50	cyp-13A2	T10B9.7	n/a	chrII 9,785,530	C. elegans CYP-13A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)