UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R07E5.5	R07E5.5	3e-55	chrIII 4,398,025	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
2	F28H6.6	F28H6.6	n/a	chrX 14,121,403	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
3	C26C6.8	C26C6.8	n/a	chrI 7,504,574	contains similarity to Pfam domains PF07653 (Variant SH3 domain) (3), PF00018 (SH3 domain) (2)contains similarity to Interpro domains IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR011511 (Variant SH3)
4	fbxa-203	W05F2.5	n/a	chrI 3,372,801	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
5	Y56A3A.16	Y56A3A.16	n/a	chrIII 11,912,267	contains similarity to Homo sapiens Isoform 1 of Pleckstrin homology domain-containing family M member 3; ENSEMBL:ENSP00000373899
6	Y69H2.1	Y69H2.1	n/a	chrV 18,621,264	contains similarity to Myxine glutinosa NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3).; SW:NU4M_MYXGL
7	ugt-37	F10D2.6	n/a	chrV 7,143,012	C. elegans UGT-37 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
8	W03D2.9	W03D2.9	n/a	chrIV 4,074,075	contains similarity to Interpro domain IPR009151 (Basigin)
9	T22C8.1	T22C8.1	n/a	chrII 8,613,779	contains similarity to Rattus norvegicus Cysteinyl leukotriene receptor 2 (CysLTR2) (RSBPT32).; SW:CLT2_RAT
10	T22B11.3	T22B11.3	n/a	chrIV 4,684,022	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
11	W02D9.9	W02D9.9	n/a	chrI 12,557,310	contains similarity to Bacteroides thetaiotaomicron Arabinose-proton symporter (Arabinose transporter).; TR:Q8AAL0
12	F31F7.3	F31F7.3	n/a	chrV 6,269,506
13	acr-3	K11G12.7	n/a	chrX 6,711,143	acr-3 encodes a non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; ACR-3 functions as a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-38, an nAChR alpha subunit, the resulting hetero-oligomer can form levamisole-gated channels; ACR-3 is a member of the UNC-29-like group of nAChR subunits.
14	R02E4.1	R02E4.1	n/a	chrX 4,103,960
15	nhr-189	F47C10.8	n/a	chrV 3,859,413	C. elegans NHR-189 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	T22H9.1	T22H9.1	n/a	chrV 361,718	contains similarity to Pfam domain PF06102 Domain of unknown function (DUF947) contains similarity to Interpro domain IPR009292 (Protein of unknown function DUF947)
17	nhr-83	F48G7.3	n/a	chrV 632,120	C. elegans NHR-83 protein; contains similarity to Pfam domains PF07914 (Protein of unknown function (DUF1679)) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR015897 (CHK kinase-like)
18	rbr-2	ZK593.4	n/a	chrIV 10,923,428	rbr-2 encodes a histone H3 lysine 4 (H3K4) demethylase that is required for normally short lifespan and reliable vulval development, that regulates genome-wide levels of H3K4 trimethylation, and that interacts genetically with CLK-2, GLP-1, LIN-15, and SEM-5; RBR-2 is orthologous to budding yeast Jhd2p, Drosophila LID, and human JARID1A (OMIM:180202), JARID1B (OMIM:605393), JARID1C (OMIM:314690, mutated in mental retardation), and JARID1D (OMIM:426000); rbr-2(tm1231) homozygotes display excess trimethylated H3K4 (H3K4me3) and erratic vulval development (either vulvaless or multivulva); rbr-2(RNAi) animals show extended lifespans, a strong synthetic multivulva and H3K4me3 phenotype in a lin-15(n765ts) mutant background at permissive temperature, and abnormally slow growth with clk-2(mn159), glp-1(or178), or sem-5(n2019) mutant backgrounds.
19	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
20	F48G7.7	F48G7.7	n/a	chrV 626,072	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
21	srxa-6	W07A8.5	n/a	chrV 20,730,954	C. elegans SRXA-6 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
22	tbx-32	ZK380.1	n/a	chrX 1,656,225	C. elegans TBX-32 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
23	R03A10.5	R03A10.5	n/a	chrX 15,448,432	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR000348 (emp24/gp25L/p24)
24	T05B4.4	T05B4.4	n/a	chrV 4,128,560
25	srh-11	R09F10.6	n/a	chrX 8,318,283	C. elegans SRH-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	T24C4.3	T24C4.3	n/a	chrIII 872,071
27	sdc-2	C35C5.1	n/a	chrX 11,528,006	The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation.
28	str-170	T08B6.7	n/a	chrIV 4,878,848	C. elegans STR-170 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	R01H10.5	R01H10.5	n/a	chrIII 10,257,869	contains similarity to Homo sapiens Similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa; ENSEMBL:ENSP00000218510
30	M116.2	M116.2	n/a	chrIV 8,399,310	contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
31	grl-28	T24A6.15	n/a	chrV 3,551,603	grl-28 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
32	T21H3.5	T21H3.5	n/a	chrV 1,159,760
33	atf-6	F45E6.2	n/a	chrX 12,482,840	atf-6 is an ortholog of mammalian ATF6alpha, a proximal sensor required for the unfolded protein response (UPR) in the endoplasmic reticulum (ER); ATF6alpha is a transmembrane protein, with a bZIP transcription factor domain in its cytosolic amino terminus that is released and activated by proteolytic cleavage upon ER stress; either ire-1 or xbp-1 deletions are synthetically lethal with atf-6 or pek-1 deletions, producing arrest in L2 larvae; RNAi of Y56A3A.2 (a S2P protease homolog) is synthetically lethal with ire-1(RNAi), consistent with the hypothesis that Y56A3A.2 cleaves ATF-6; atf-6 regulates few genes that are transcriptionally induced by UPR, but regulates roughly one-quarter of genes that require UPR constitutively; pdr-1 transcripts are strongly upregulated in a atf-6(ok551) mutant background, but atf-6(ok551);pdr-1(lg103) double mutants have a grossly normal phenotype ; atf-6 is dispensable for proper localization of GLR-1 glutamate receptors.
34	bath-33	C08E3.3	n/a	chrII 1,605,408	C. elegans BATH-33 protein; contains similarity to Pfam domains PF00917 (MATH domain) , PF00651 (BTB/POZ domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
35	F38C2.1	F38C2.1	n/a	chrIV 16,249,570	contains similarity to Carnobacterium piscicola ATP-dependent translocator.; TR:Q46317
36	str-101	Y6E2A.2	n/a	chrV 15,711,366	C. elegans STR-101 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	W02D9.8	W02D9.8	n/a	chrI 12,558,734	contains similarity to Interpro domain IPR004692 (Preprotein translocase SecG subunit)
38	C13C4.6	C13C4.6	n/a	chrV 12,123,359	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
39	nhr-76	C05G6.1	n/a	chrIV 630,739	C. elegans NHR-76 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
40	C17A2.7	C17A2.7	n/a	chrII 3,842,652	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domains IPR004101 (Mur ligase, C-terminal), IPR002485 (Protein of unknown function DUF13)
41	ZK1307.4	ZK1307.4	n/a	chrII 9,651,306	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
42	fbxb-118	W06A11.3	n/a	chrII 4,063,201	C. elegans FBXB-118 protein ;
43	sri-25	C41G6.10	n/a	chrV 15,218,422	C. elegans SRI-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	gstk-2	D2024.7	n/a	chrIV 7,241,341	C. elegans GSTK-2 protein; contains similarity to Pfam domain PF01323 DSBA-like thioredoxin domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001853 (DSBA oxidoreductase), IPR014440 (HCCA isomerase/glutathione S-transferase kappa)
45	nhr-32	K08H2.8	n/a	chrX 13,254,014	C. elegans NHR-32 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
46	C08G5.1	C08G5.1	n/a	chrII 736,664	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
47	T07G12.5	T07G12.5	n/a	chrIV 10,543,255	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
48	C50C3.7	C50C3.7	n/a	chrIII 8,160,210	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domains IPR000300 (Inositol polyphosphate related phosphatase), IPR005135 (Endonuclease/exonuclease/phosphatase)
49	C04B4.4	C04B4.4	n/a	chrX 12,291,546	contains similarity to Saccharomyces cerevisiae Nucleolar protein involved in exit from mitosis; SGD:YJL076W
50	K02F6.6	K02F6.6	n/a	chrII 2,530,385	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)