UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R07E5.13	R07E5.13	2e-84	chrIII 4,414,076	This gene encodes a homolog of mammalian BRAIN PROTEIN 44-LIKE (BRP44L).
2	K04G2.6	K04G2.6	n/a	chrI 8,041,954	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
3	C27A2.1	C27A2.1	n/a	chrII 5,064,604	contains similarity to Pfam domain PF02463 RecF/RecN/SMC N terminal domain contains similarity to Interpro domain IPR003395 (RecF/RecN/SMC protein, N-terminal)
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	D1043.1	D1043.1	n/a	chrII 11,585,601	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
6	F33H2.2	F33H2.2	n/a	chrI 15,025,433	contains similarity to Homo sapiens Protein FAM91A1; ENSEMBL:ENSP00000335082
7	B0273.3	B0273.3	n/a	chrIV 5,485,115	contains similarity to Tetraodon nigroviridis Chromosome 18 SCAF15038, whole genome shotgun sequence. (Fragment).; TR:Q4RJG8
8	stl-1	F30A10.5	n/a	chrI 9,487,412	C. elegans STL-1 protein; contains similarity to Pfam domain PF01145 SPFH domain / Band 7 family contains similarity to Interpro domains IPR001107 (Band 7 protein), IPR001972 (Stomatin)
9	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
10	ZK1067.3	ZK1067.3	n/a	chrII 9,224,144	contains similarity to Mus musculus Serine/threonine-protein kinase Nek9 (EC 2.7.1.37) (NimA-relatedsprotein kinase 9).; SW:NEK9_MOUSE
11	rde-1	K08H10.7	n/a	chrV 9,989,751	rde-1 encodes a novel, conserved protein that is a member of the PIWI/STING/Argonaute/Zwille/eIF2c family of proteins; rde-1 activity is required for RNA-mediated interference (RNAi), likely at a point after small interfering RNAs (siRNAs) have been produced from dsRNA triggers; RDE-1 interacts with RDE-4 in vivo and its activity is also required for accumulation of dsRNA bound to RDE-4.
12	R06B9.3	R06B9.3	n/a	chrII 13,759,726	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000694 (Proline-rich region), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
13	cyn-7	Y75B12B.2	n/a	chrV 15,186,997	cyn-7 encodes a cyclophilin A isoform; while not tested for peptidyl-prolyl isomerase activity in vitro, it is very similar to CYN-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYN-7 was required for embryonic viability in one set of mass RNAi assays.
14	K02B2.1	K02B2.1	n/a	chrIV 5,942,943	contains similarity to Pfam domains PF01591 (6-phosphofructo-2-kinase) , PF00300 (Phosphoglycerate mutase family) contains similarity to Interpro domains IPR016260 (Bifunctional 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-phosphatase), IPR001345 (Phosphoglycerate/bisphosphoglycerate mutase), IPR003094 (Fructose-2,6-bisphosphatase), IPR013079 (6-phosphofructo-2-kinase), IPR013078 (Phosphoglycerate mutase)
15	vps-33.2	C56C10.1	n/a	chrII 6,602,269	C. elegans VPS-33.2 protein; contains similarity to Pfam domain PF00995 Sec1 family contains similarity to Interpro domain IPR001619 (Sec1-like protein)
16	mut-14	C14C11.6	n/a	chrV 5,659,724	mut-14 mutants exhibit germline transposon activation, a deficient response to RNAi, resistance to co-suppression, and transgene desilencing.
17	cdd-2	F49E8.4	n/a	chrIV 7,547,502	A functional cytidine deaminase that affects morphology of embryos; it is expressed at all life cycle stages.
18	sna-2	T13F2.7	n/a	chrIV 9,776,092	sna-2 encodes an snRNP-binding protein (SNA-2/SL75p) homologous to Ascaris SL95p (SL 175kd); SNA-2 is found in at least two Sm snRNPs, SL1 and Y, but not in SL2; in snRNP SL1, SNA-2 associates with the SNA-1/SL21p protein, while associating with SUT-1/SL26p (a paralog of SNA-1) in snRNP Y; sna-2(RNAi) is lethal; SNA-2 can bind either SNA-1 or SUT-1 even in the absence of RNA.
19	dpf-5	R11E3.8	n/a	chrIV 4,804,689	dpf-5 encodes a putative acylamino-acid-releasing enzyme (AARE; EC 3.4.19.1), orthologous to human APEH, with no obvious function in mass RNAi assays.
20	C48B4.10	C48B4.10	n/a	chrIII 9,563,945	contains similarity to Homo sapiens Transmembrane 9 superfamily protein member 2 precursor; ENSEMBL:ENSP00000245361
21	F26G1.1	F26G1.1	n/a	chrII 4,792,961	contains similarity to Aedes aegypti Esophageal cancer associated protein.; TR:Q16QZ5
22	C24F3.4	C24F3.4	n/a	chrIV 10,217,118	contains similarity to Pfam domains PF00795 (Carbon-nitrogen hydrolase) , PF02540 (NAD synthase) contains similarity to Interpro domains IPR003010 (Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR003694 (NAD+ synthase), IPR014445 (Glutamine-dependent NAD(+) synthetase, GAT region)
23	Y106G6H.8	Y106G6H.8	n/a	chrI 10,452,513	contains similarity to Pfam domain PF04241 Protein of unknown function (DUF423) contains similarity to Interpro domain IPR006696 (Protein of unknown function DUF423)
24	npp-14	C03D6.4	n/a	chrI 9,662,535	npp-14 is orthologous to the human gene NUCLEOPORIN, 214-KD (NUP214; OMIM:114350), which encodes part of the nucleopore complex mediating nucleocytoplasmic transport; NUP214, as a fusion gene with DEK (OMIM:125264), is found in a subset of acute myeloid leukemia.
25	F32A7.4	F32A7.4	n/a	chrI 14,841,491	contains similarity to Pfam domain PF09243 Mitochondrial small ribosomal subunit Rsm22 contains similarity to Interpro domain IPR015324 (Ribosomal protein Rsm22, bacterial-type)
26	F44E2.8	F44E2.8	n/a	chrIII 8,849,158	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
27	ZK1320.3	ZK1320.3	n/a	chrII 9,659,772
28	ZK1193.2	ZK1193.2	n/a	chrX 411,499	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR002049 (EGF-like, laminin), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans), IPR002035 (von Willebrand factor, type A)
29	pbs-4	T20F5.2	n/a	chrI 3,909,198	pbs-4 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-4 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-4 activity via RNAi indicates that, in C. elegans, PBS-4 is required for embryonic, germline, and larval development.
30	apc-2	K06H7.6	n/a	chrIII 8,082,080	apc-2 encodes an ortholog of subunit 2 of anaphase-promoting complex (APC, a cyclin-specific E3 RING ubiquitin ligase); APC-2 and S. cerevisiae's Apc2p have 32% identity in their cullin domains (considered crucial for function), but otherwise share no obvious similarity; inactivating apc-2 with RNAi causes embryos to arrest at the meiotic one-cell stage, implying that APC-2 is required for the metaphase-to-anaphase transition of meiosis I; this RNAi phenotype of apc-2 is shared by apc-1, apc-4, apc-11, cdc-16, cdc-23, and cdc-27; by analogy with other APC subunits with hypomorphic alleles, APC-2 is likely to be required for asymmetrical segregation of cell fate determinants in two-cell embryos.
31	C44E4.3	C44E4.3	n/a	chrI 4,639,174	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
32	W01A11.1	W01A11.1	n/a	chrV 6,500,809	contains similarity to Pfam domains PF06441 (Epoxide hydrolase N terminus) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR016292 (Epoxide hydrolase), IPR000073 (Alpha/beta hydrolase fold-1), IPR000639 (Epoxide hydrolase-like), IPR010497 (Epoxide hydrolase, N-terminal)
33	T01G1.3	T01G1.3	n/a	chrIV 11,368,676	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000694 (Proline-rich region), IPR002110 (Ankyrin), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
34	Y57G11C.4	Y57G11C.4	n/a	chrIV 14,766,103	contains similarity to Pfam domain PF05008 Vesicle transport v-SNARE protein contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR007705 (Vesicle transport v-SNARE)
35	CD4.8	CD4.8	n/a	chrV 5,600,286	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
36	F55A3.7	F55A3.7	n/a	chrI 10,786,484	contains similarity to Pfam domain PF08644 FACT complex subunit (SPT16/CDC68) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR013953 (FACT complex subunit Spt16p/Cdc68p)
37	T19B10.8	T19B10.8	n/a	chrV 11,243,290	contains similarity to Pfam domain PF07819 PGAP1-like protein contains similarity to Interpro domain IPR012908 (PGAP1-like)
38	K11H3.4	K11H3.4	n/a	chrIII 9,835,521	contains similarity to Pfam domain PF02213 (GYF domain)
39	C14B1.6	C14B1.6	n/a	chrIII 3,716,084	contains similarity to Interpro domain IPR008162 (Inorganic pyrophosphatase)
40	rec-8	W02A2.6	n/a	chrIV 13,351,138	rec-8 encodes a meiosis-specific cohesin complex subunit orthologous to Saccharomyces cerevisiae and Schizosaccharomyces pombe Rec8p; REC-8 is essential for pairing of homologoues and sister chromatids during meiosis and thus for proper chromosome disjunction; in the germline, REC-8 associates with chromatin of transition zone nuclei, and co-localizes with SMC-1 along the longitudinal axes of synapsed chromosomes at pachytene and in a cruciform pattern at diakinesis; REC-8 localization to chromatin is dependent upon TIM-1, a HEAT/Armadillo repeat-containing protein related to Drosophila TIMELESS, and additionally, REC-8 and SCC-3 are mutually required for chromatin localization; REC-8 cleavage and degradation during meiosis I is dependent on the AIR-2 aurora-like kinase and during meiosis II on AIR-2 and the PLK-1 polo-like kinase.
41	W02G9.4	W02G9.4	n/a	chrV 2,668,540	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
42	R08D7.1	R08D7.1	n/a	chrIII 8,966,795	contains similarity to Drosophila pseudoobscura GA12417-PA (Fragment).; TR:Q293H8
43	ZK856.10	ZK856.10	n/a	chrV 10,206,112	contains similarity to Pfam domains PF08292 (RNA polymerase III subunit Rpc25) , PF03876 (RNA polymerase Rpb7-like, N-terminal domain) contains similarity to Interpro domains IPR003029 (S1, RNA binding), IPR005576 (RNA polymerase Rpb7, N-terminal), IPR013238 (RNA polymerase III, subunit Rpc25)
44	mrp-4	F21G4.2	n/a	chrX 9,886,947	mrp-4 encodes a putative member of subfamily C of the ATP-binding cassette transporters; MRP-4 is required, redundantly with its paralog WHT-2, for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; hermaphrodites subjected to double wht-2(RNAi) mrp-4(RNAi) are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them; in mammalian eicosanoid signalling, subfamily C ABC transporters are required for PUFA and eicosanoid transport.
45	C36A4.5	C36A4.5	n/a	chrIII 3,846,247	contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR000694 (Proline-rich region), IPR005819 (Histone H5)
46	ent-1	ZK809.4	n/a	chrIV 11,654,417	ent-1 encodes a predicted equilibrative nucleoside transporter 1 that affects growth.
47	htp-1	F41H10.10	n/a	chrIV 5,390,947	C. elegans HTP-1 protein; contains similarity to Pfam domain PF02301 HORMA domain contains similarity to Interpro domain IPR003511 (DNA-binding HORMA)
48	E02H1.2	E02H1.2	n/a	chrII 9,588,980	contains similarity to Pfam domain PF01926 GTPase of unknown function contains similarity to Interpro domains IPR009019 (K Homology, prokaryotic type), IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR002127 (Tetracycline resistance protein, TetO/TetQ/TetM), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR015946 (K homology-like, alpha/beta)
49	xtr-2	F17A2.1	n/a	chrX 12,316,529	xtr-2 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
50	W02D9.3	W02D9.3	n/a	chrI 12,536,484	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)