UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	unc-7	R07D5.1	0	chrX 15,134,407	unc-7 encodes an innexin required for gap junction formation in invertebrates; UNC-7 is also required for normal locomotion, egg-laying, inhibition of feeding by tapping, avermectin sensitivity, and ivermectin sensitivity, as well as for the antagonism of UNC-79 and UNC-80 activity by volatile anesthetics; unc-7 is genetically required, and transcribed in, neurons rather than muscle cells, from larval stages L1 through L4; homologs of UNC-7 include Drosophila OGRE and SHAKING-B, as well as 24 C. elegans paralogs (including EAT-5, UNC-9, and INX-1 through INX-20); UNC-7 genetically interacts with UNC-124, and unc-7 mutants are phenotypically similar to unc-9 and unc-124 mutants; UNC-7 genetically interacts with AVR-14 and GLC-1 in the response to ivermectin.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	zag-1	F28F9.1	n/a	chrIV 3,858,673	zag-1 encodes a homeodomain protein of the ZFH class which consists of a homeodomain flanked by two clusters of C2H2-type zinc fingers and is related to transcriptional repressors encoded by Drosophila zfh-1 and the vertebrate ZEB genes; ZAG-1 is required for locomotion, for neuronal differentiation, and for proper axonal branching and fasciculation; from late embryogenesis through adult stages of development, ZAG-1 is expressed dynamically in head and tail neurons and in the intestinal and anal depressor muscles.
4	C34F6.10	C34F6.10	n/a	chrX 11,233,244	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR000694 (Proline-rich region)
5	abch-1	C56E6.5	n/a	chrII 6,530,223	C. elegans ABCH-1 protein; contains similarity to Interpro domain IPR003439 (ABC transporter-like)
6	rab-11.2	W04G5.2	n/a	chrI 11,633,357	C. elegans RAB-11.2 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
7	F45D3.2	F45D3.2	n/a	chrV 12,541,972	contains similarity to Dictyocaulus viviparus Putative uncharacterized protein.; TR:Q6E6T3
8	clk-1	ZC395.2	n/a	chrIII 5,278,572	clk-1 encodes the C. elegans ortholog of COQ7/CAT5, a highly conserved demethoxyubiquinone (DMQ) hydroxylase that is necessary for the biosynthesis of ubiquinone (coenzyme Q, Q9) from 5-demethoxyubiquinone (DMQ9); in C. elegans, CLK-1 activity is required for normal physiological rates of growth, development, behavior, and aging, as well as for normal brood sizes.
9	R08B4.3	R08B4.3	n/a	chrX 11,119,911	contains similarity to Homo sapiens 23 kDa protein; VG:OTTHUMP00000170038
10	gpa-5	F53B1.7	n/a	chrX 2,119,972	gpa-5 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in AWA, with faint expression in ASI.
11	srx-9	R13D7.6	n/a	chrV 7,394,485	C. elegans SRX-9 protein; contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
12	T23F4.1	T23F4.1	n/a	chrII 1,167,834	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
13	pax-2	K06B9.5	n/a	chrIV 4,202,013	C. elegans PAX-2 protein; contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
14	Y57G7A.1	Y57G7A.1	n/a	chrII 1,299,102
15	K02F6.4	K02F6.4	n/a	chrII 2,541,208	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
16	srx-67	K07C6.10	n/a	chrV 3,917,627	C. elegans SRX-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
17	tpst-2	F42G9.8	n/a	chrIII 772,135	C. elegans TPST-2 protein ; contains similarity to Drosophila melanogaster Flybase gene name is Tango13-PC;; FLYBASE:CG32632
18	K09H11.4	K09H11.4	n/a	chrV 5,724,796	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
19	grl-14	T03D8.4	n/a	chrV 20,822,062	grl-14 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; GRL-14 is expressed in intestine, head mesodermal cell, hypodermis, seam cells, and uterine muscle, larval arcade cells and reproductive system, and the developing vulva; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
20	fbxa-171	C38D9.1	n/a	chrV 17,564,573	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
21	K01C8.2	K01C8.2	n/a	chrII 8,268,517	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
22	ZK1128.7	ZK1128.7	n/a	chrIII 10,137,921	contains similarity to Pfam domain PF00011 Hsp20/alpha crystallin family contains similarity to Interpro domains IPR002068 (Heat shock protein Hsp20), IPR008978 (HSP20-like chaperone), IPR001436 (Alpha crystallin/Heat shock protein)
23	F39B3.2	F39B3.2	n/a	chrX 17,569,704	contains similarity to Pfam domains PF00001 (7 transmembrane receptor (rhodopsin family)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
24	ZC482.4	ZC482.4	n/a	chrIII 12,766,680	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
25	T07G12.4	T07G12.4	n/a	chrIV 10,537,682	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
26	srt-29	C24B9.5	n/a	chrV 2,718,264	C. elegans SRT-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR001991 (Sodium:dicarboxylate symporter)
27	gcy-6	B0024.6	n/a	chrV 10,311,299	gcy-6 encodes a predicted guanylate cyclase; expressed in the ASEL neurons.
28	F52H2.7	F52H2.7	n/a	chrX 2,569,600	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
29	sre-5	B0212.2	n/a	chrIV 3,566,503	C. elegans SRE-5 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
30	moc-2	W01A11.6	n/a	chrV 6,503,257	C. elegans MOC-2 protein; contains similarity to Pfam domain PF00994 Probable molybdopterin binding domain contains similarity to Interpro domains IPR008284 (Molybdenum cofactor biosynthesis, conserved site), IPR001453 (Molybdopterin binding)
31	nhr-96	F44C8.11	n/a	chrV 2,234,310	nhr-96 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
32	F21D9.1	F21D9.1	n/a	chrV 19,267,093	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
33	C36C9.5	C36C9.5	n/a	chrX 1,701,859
34	srw-24	C41G6.7	n/a	chrV 15,224,639	C. elegans SRW-24 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
35	gcy-3	R134.1	n/a	chrII 9,504,941	gcy-3 is predicted to encode a guanylate cyclase.
36	Y16B4A.2	Y16B4A.2	n/a	chrX 14,766,829	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
37	dpy-22	F47A4.2	n/a	chrX 9,816,134	dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression.
38	set-30	ZC8.3	n/a	chrX 5,001,358	set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes.
39	ZC487.3	ZC487.3	n/a	chrV 6,723,598
40	K06A9.3	K06A9.3	n/a	chrX 1,534,681	contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site)
41	Y37D8A.3	Y37D8A.3	n/a	chrIII 12,833,196	contains similarity to Methanosarcina mazei Conserved protein.; TR:Q8Q0P1
42	srt-16	C50H11.11	n/a	chrV 3,064,037	C. elegans SRT-16 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	str-248	C55A1.3	n/a	chrV 15,628,858	C. elegans STR-248 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	srab-7	C36C5.11	n/a	chrV 3,154,327	C. elegans SRAB-7 protein ;
45	srw-136	K12D9.10	n/a	chrV 3,009,736	C. elegans SRW-136 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
46	T27C4.2	T27C4.2	n/a	chrV 3,729,612
47	F18F11.4	F18F11.4	n/a	chrIV 332,622	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
48	R04A9.3	R04A9.3	n/a	chrX 378,980
49	F48B9.8	F48B9.8	n/a	chrX 2,175,203	contains similarity to Homo sapiens Protein FAM8A1; ENSEMBL:ENSP00000259963
50	F32D8.1	F32D8.1	n/a	chrV 10,882,070	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)