UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	set-14	R06F6.4	0	chrII 10,794,856	set-14 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-14 is paralogous to SET-10, SET-18, and SET-30; SET-14 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays.
2	math-24	C46F9.3	n/a	chrII 1,901,084	The C46F9.3 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
3	cul-4	F45E12.3	n/a	chrII 7,303,864	cul-4 encodes one of six C. elegans cullin proteins; CUL-4 activity is essential for negative regulation of DNA-replication licensing and thus, for maintenance of genome stability; in regulating DNA replication, CUL-4 functions as part of a CUL-4/DDB-1 ubiquitin ligase complex that degrades the replication licensing factor CDT-1 and indirectly promotes nuclear export of the replication licensing factor CDC-6 by negatively regulating the levels of the CKI-1 CDK inhibitor; cul-4 mRNA is expressed throughout development with highest levels seen in embryos and lower levels seen in larvae and adults; maternal cul-4 mRNA is present in early embryos and larval and adult mRNA is most notably present in the intestine and germ line.
4	R52.2	R52.2	n/a	chrII 2,127,157	contains similarity to Pfam domains PF03564 (Protein of unknown function (DUF1759)) , PF05585 (Protein of unknown function (DUF1758)) contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR008737 (Protein of unknown function DUF1758), IPR005312 (Protein of unknown function DUF1759), IPR001878 (Zinc finger, CCHC-type)
5	snx-3	W06D4.5	n/a	chrI 9,064,058	C. elegans SNX-3 protein; contains similarity to Pfam domain PF00787 PX domain contains similarity to Interpro domain IPR001683 (Phox-like)
6	F16A11.1	F16A11.1	n/a	chrI 9,398,979	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001870 (B302, (SPRY)-like), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003877 (SPla/RYanodine receptor SPRY)
7	Y102A5C.4	Y102A5C.4	n/a	chrV 16,923,224	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
8	nhl-1	F54G8.4	n/a	chrIII 9,150,557	The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.
9	C09G9.2	C09G9.2	n/a	chrIV 8,868,853	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
10	mrp-2	F57C12.4	n/a	chrX 568,214	mrp-2 encodes a predicted multidomain transmembrane protein that is a member of the ATP-binding cassette (ABC) superfamily of transport proteins and is homologous to the human multidrug resistance-associated protein 1 (MRP1, OMIM:158343); by homology, MRP-2 is predicted to function as a membrane pump that couples the energy of ATP hydrolysis to membrane transport; as loss of MRP-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of MRP-2 in C. elegans development and/or behavior is not yet known; mrp-2 expression is, however, upregulated early in the exit from the alternative dauer stage and then remains induced, suggesting that MRP-2 activity is required for the transition to, and maintenance of, a more active metabolic state.
11	exos-7	F31D4.1	n/a	chrV 20,835,609	C. elegans EXOS-7 protein; contains similarity to Pfam domain PF01138 3' exoribonuclease family, domain 1 contains similarity to Interpro domain IPR001247 (Exoribonuclease, phosphorolytic domain 1)
12	F52G3.3	F52G3.3	n/a	chrX 16,946,368	contains similarity to Medicago truncatula Putative uncharacterized protein.; TR:A2Q378
13	str-25	F44G3.11	n/a	chrV 16,116,262	C. elegans STR-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	F43C1.3	F43C1.3	n/a	chrIII 4,244,006	F43C1.3 encodes a protein containing an HIT-type zinc finger domain and a coiled-coil region; loss of F43C1.3 activity via RNAi results in slower than normal growth rates.
15	trm-1	ZC376.5	n/a	chrV 14,184,351	C. elegans TRM-1 protein; contains similarity to Pfam domain PF02005 N2,N2-dimethylguanosine tRNA methyltransferase contains similarity to Interpro domain IPR002905 (N2,N2-dimethylguanosine tRNA methyltransferase)
16	F19C7.3	F19C7.3	n/a	chrIV 4,598,308	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
17	srh-187	F10G2.8	n/a	chrV 7,339,214	C. elegans SRH-187 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	F36H2.2	F36H2.2	n/a	chrI 9,247,697	contains similarity to Pfam domain PF01733 Nucleoside transporter contains similarity to Interpro domains IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter), IPR016196 (MFS general substrate transporter)
19	cyp-25A4	C36A4.6	n/a	chrIII 3,850,968	C. elegans CYP-25A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
20	lgc-14	T01H10.2	n/a	chrX 12,112,417	C. elegans LGC-14 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
21	R119.1	R119.1	n/a	chrI 360,571	contains similarity to Interpro domain IPR009080 (Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)
22	C05C8.5	C05C8.5	n/a	chrV 7,233,733	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
23	ZC373.3	ZC373.3	n/a	chrX 10,061,060	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	F55G1.6	F55G1.6	n/a	chrIV 7,474,219	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR011016 (Zinc finger, variant RING-type)
25	R11A8.2	R11A8.2	n/a	chrIV 10,359,115	contains similarity to Interpro domains IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR000467 (D111/G-patch)
26	R144.5	R144.5	n/a	chrIII 5,000,320	contains similarity to Homo sapiens Isoform 1 of Smith-Magenis syndrome chromosomal region candidate gene 8 protein; ENSEMBL:ENSP00000379048
27	C05C8.8	C05C8.8	n/a	chrV 7,253,723	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
28	nspb-3	F38A5.5	n/a	chrIV 6,594,788	C. elegans NSPB-3 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
29	C35D10.6	C35D10.6	n/a	chrIII 4,859,975	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
30	sre-55	C50E10.7	n/a	chrII 12,330,123	C. elegans SRE-55 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
31	K09E3.4	K09E3.4	n/a	chrX 17,119,682
32	edc-3	R05D11.8	n/a	chrI 8,603,637	C. elegans EDC-3 protein; contains similarity to Interpro domain IPR010920 (Like-Sm ribonucleoprotein-related, core)
33	T05D4.3	T05D4.3	n/a	chrIII 13,568,545	contains similarity to Interpro domain IPR005838 (Type III secretion system inner membrane P protein)
34	F55A12.5	F55A12.5	n/a	chrI 5,347,791	contains similarity to Gallus gallus Nucleolin (Protein C23).; SW:P15771
35	F46F11.8	F46F11.8	n/a	chrI 5,625,448
36	msh-2	H26D21.2	n/a	chrI 3,695,931	The msh-2 gene encodes a DNA mismatch repair protein homolog that is orthologous to human MSH2 (OMIM:120435); mutation of the human MSH2 gene leads to hereditary non-polyposis colon cancer (OMIM:120436).
37	ZK1248.15	ZK1248.15	n/a	chrII 5,837,633	contains similarity to Pfam domain PF00397 WW domain contains similarity to Interpro domains IPR006596 (Nucleotide binding protein, PINc), IPR001202 (WW/Rsp5/WWP)
38	F25G6.9	F25G6.9	n/a	chrV 8,567,613	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
39	R05D3.1	R05D3.1	n/a	chrIII 8,384,526	contains similarity to Pfam domains PF00521 (DNA gyrase/topoisomerase IV, subunit A) , PF02518 (Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) , PF00204 (DNA gyrase B) contains similarity to Interpro domains IPR002205 (DNA topoisomerase, type IIA, subunit A or C-terminal), IPR013506 (DNA topoisomerase, type IIA, subunit B, region 2), IPR001241 (DNA topoisomerase, type IIA, subunit B or N-terminal), IPR011558 (DNA topoisomerase, type IIA, subunit B, conserved region), IPR013758 (DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta), IPR013757 (DNA topoisomerase, type IIA, subunit A, alpha-helical), IPR003594 (ATP-binding region, ATPase-like), IPR013759 (DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta), IPR001154 (DNA topoisomerase II, eukaryotic-type), IPR014721 (Ribosomal protein S5 domain 2-type fold), IPR013760 (DNA topoisomerase, type IIA, central)
40	T13F2.2	T13F2.2	n/a	chrIV 9,797,072	contains similarity to Pfam domain PF02229 Transcriptional Coactivator p15 (PC4) contains similarity to Interpro domains IPR003173 (Transcriptional coactivator p15), IPR009044 (ssDNA-binding transcriptional regulator)
41	C10B5.3	C10B5.3	n/a	chrV 8,584,165
42	ZK822.1	ZK822.1	n/a	chrIV 11,920,082	contains similarity to Homo sapiens myosin, heavy polypeptide 7B, cardiac muscle, beta; ENSEMBL:ENSP00000262873
43	T02E1.2	T02E1.2	n/a	chrI 8,221,514	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJZ2
44	mab-21	F35G12.6	n/a	chrIII 4,601,861	mab-21 encodes a novel protein that is a member of a highly conserved family of proteins with Drosophila and vertebrate orthologs; MAB-21 is cell-autonomously required for specifying the identity of sensory ray 6 in the male tail, and also for backward locomotion, normal body morphology, fecundity, and embryonic morphogenesis; MAB-21 expression begins in embryonic hypodermal cells and continues in larval and adult animals in hypodermis, anterior and ventral cord neurons, some body wall muscles, and ray cells.
45	lgc-45	W10G11.16	n/a	chrII 3,566,681	C. elegans LGC-45 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
46	T09A5.9	T09A5.9	n/a	chrII 7,858,979	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal)
47	T07F10.3	T07F10.3	n/a	chrV 12,869,009	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
48	math-36	R52.8	n/a	chrII 2,118,724	C. elegans MATH-36 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
49	nth-1	R10E4.5	n/a	chrIII 4,292,462	C. elegans NTH-1 protein; contains similarity to Pfam domains PF00633 (Helix-hairpin-helix motif) , PF00730 (HhH-GPD superfamily base excision DNA repair protein) contains similarity to Interpro domains IPR011257 (DNA glycosylase), IPR003651 (Iron-sulphur cluster loop), IPR000445 (Helix-hairpin-helix motif), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR004036 (Endonuclease III, conserved site-2), IPR003265 (HhH-GPD)
50	ZK1128.1	ZK1128.1	n/a	chrIII 10,113,863	contains similarity to Pfam domain PF02636 Uncharacterized ACR, COG1565 contains similarity to Interpro domain IPR003788 (Protein of unknown function DUF185)