UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R06A10.4	R06A10.4	0	chrI 1,092,733	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
2	H03G16.1	H03G16.1	n/a	chrX 15,054,187	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
3	F45G2.10	F45G2.10	n/a	chrIII 13,438,200	contains similarity to Pfam domain PF01883 Domain of unknown function DUF59 contains similarity to Interpro domain IPR002744 (Protein of unknown function DUF59)
4	mbr-1	T01C1.2	n/a	chrX 10,720,732	C. elegans MBR-1 protein; contains similarity to Pfam domain PF05225 helix-turn-helix, Psq domain contains similarity to Interpro domains IPR011526 (Helix-turn-helix, Psq-like), IPR007889 (Helix-turn-helix, Psq)
5	ina-1	F54G8.3	n/a	chrIII 9,170,331	ina-1 encodes one of two C. elegans alpha integrin subunits; during development, ina-1 activity is required for migration of a number of cell types, including neurons, coelomocyte precursors, and the distal tip cells of the somatic gonad; in addition, ina-1 is required for axon fasciculation and morphogenesis of structures such as the head, pharynx, egg-laying apparatus, and male tail; INA-1 coimmunoprecipitates with the PAT-3 beta integrin subunit suggesting that, in vivo, INA-1 and PAT-3 function as a heterodimer to regulate cell migration and tissue morphogenesis; INA-1 is expressed in many tissues, including neurons, the gonad, and the pharyngeal basement membrane; expression begins during gastrulation and continues through to adulthood.
6	K02D7.5	K02D7.5	n/a	chrIV 309,359	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
7	str-119	C13B7.5	n/a	chrV 2,427,301	C. elegans STR-119 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	C33C12.9	C33C12.9	n/a	chrII 2,188,303	contains similarity to Pfam domain PF05175 Methyltransferase small domain contains similarity to Interpro domains IPR007848 (Methyltransferase small), IPR004557 (Putative methylase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
9	T16G1.5	T16G1.5	n/a	chrV 12,938,559	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
10	F17C11.6	F17C11.6	n/a	chrV 10,955,512	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9ZT77
11	ZC482.7	ZC482.7	n/a	chrIII 12,752,251	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
12	srv-34	F13A7.3	n/a	chrV 16,373,569	C. elegans SRV-34 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000355 (Chemokine receptor)
13	C53B7.6	C53B7.6	n/a	chrX 6,868,654
14	F26F2.3	F26F2.3	n/a	chrV 20,561,363	contains similarity to Saccharomyces cerevisiae Profilin synthetic lethal protein, has region of coiled-coil structure; subunit of the Exocyst complex--the Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70 and is required for exocytosis; SGD:YER008C
15	T04F3.4	T04F3.4	n/a	chrV 11,762,441	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
16	H08J19.1	H08J19.1	n/a	chrX 15,643,559	contains similarity to Homo sapiens formin-like 3 isoform 1; ENSEMBL:ENSP00000335655
17	F49E12.8	F49E12.8	n/a	chrII 8,393,450	contains similarity to Homo sapiens Hypothetical protein KIAA0335; TR:O15044
18	sre-37	F15A4.3	n/a	chrII 12,466,610	C. elegans SRE-37 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
19	ZK1240.5	ZK1240.5	n/a	chrII 2,317,121	contains similarity to Interpro domain IPR000315 (Zinc finger, B-box)
20	lin-1	C37F5.1	n/a	chrIV 2,288,106	lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development.
21	W04G5.9	W04G5.9	n/a	chrI 11,644,012	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
22	C10E2.4	C10E2.4	n/a	chrX 16,750,349
23	srx-13	C44B12.4	n/a	chrIV 1,116,817	C. elegans SRX-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
24	srh-38	C31B8.11	n/a	chrV 2,921,646	C. elegans SRH-38 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	srt-70	B0238.6	n/a	chrV 5,258,776	C. elegans SRT-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	ikb-1	C04F12.3	n/a	chrI 9,687,053	ikb-1 encodes an ortholog of human BCL3 (OMIM:109560) that physically interacts with the checkpoint protein MRT-2; ikb-1(nr2019) and ikb-1(nr2027) mutants display no obvious phenotype other than shortened lifespan; mutation of BCL3 is frequently associated with recurring translocations found in the neoplastic cells of patients with chronic lymphocytic leukemia, and has been implicated in cell cycle control (perhaps via apoptosis).
27	C34B2.9	C34B2.9	n/a	chrI 10,701,670	contains similarity to Interpro domain IPR001904 (Paxillin)
28	R05A10.5	R05A10.5	n/a	chrIV 14,169,839	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
29	F09G8.5	F09G8.5	n/a	chrIII 8,256,200	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal), IPR010916 (TonB box, conserved site)
30	puf-4	M4.2	n/a	chrIV 3,207,566	C. elegans PUF-4 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
31	E02H4.5	E02H4.5	n/a	chrX 14,254,507	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IBC6
32	mel-26	ZK858.4	n/a	chrI 9,134,137	mel-26 encodes a MATH and BTB/POZ domain-containing protein that functions as a novel substrate-specific adaptor of the CUL-3-containing E3 ubiquitin ligase; MEL-26 is required maternally for formation of mitotic spindles in the early embryo, and as a component of a ubiquitin ligase complex, for degradation of the microtubule-severing protein MEI-1 at the meiosis to mitosis transition; MEL-26 is also required maternally for embryonic morphogenesis; since MEL-26 contains a meprin-associated Traf homology (MATH) domain, it might be involved in apoptosis.
33	F38A1.13	F38A1.13	n/a	chrIV 1,265,538
34	F59B2.13	F59B2.13	n/a	chrIII 9,025,413	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
35	F11D11.4	F11D11.4	n/a	chrV 18,762,417	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
36	fpn-1.2	R09B5.4	n/a	chrV 1,463,421	R09B5.4 is orthologous to the human gene HYPOTHETICAL PROTEIN (SLC11A3; OMIM:604653), which when mutated leads to disease.
37	srz-15	C32H11.2	n/a	chrIV 12,916,637	C. elegans SRZ-15 protein ;
38	C53A5.11	C53A5.11	n/a	chrV 14,563,580	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF07646 (Kelch motif) (3)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
39	ZK470.4	ZK470.4	n/a	chrX 4,139,617
40	cah-1	F54D8.4	n/a	chrIII 5,084,208	cah-1 encodes a member of the carbonic anhydrase family.
41	nhr-116	F09C6.9	n/a	chrV 16,913,761	C. elegans NHR-116 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
42	npr-1	C39E6.6	n/a	chrX 4,768,551	npr-1 encodes a predicted G protein-coupled neuropeptide receptor that is homologous to the mammalian neuropeptide Y (NPY) receptor (OMIM:162641) required for regulating anxiety, food consumption, and pain sensation; in C. elegans, NPR-1 is involved in ethological variations of social behavior such as social versus solitary feeding; NPR-1 also affects some aspect of UNC-6/netrin-mediated branching of motor neurons, as strong npr-1 mutations can suppress abnormal migration of ventral nerve cord neurons induced by overexpression of UNC-6 lacking domain C; NPR-1 is expressed predominantly in the nervous system, and particularly in the AQR, PQR, and URX neurons that are exposed to the body fluid.
43	str-37	C50B6.12	n/a	chrV 13,328,296	C. elegans STR-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	C50E3.2	C50E3.2	n/a	chrV 7,610,647	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
45	str-185	R08C7.7	n/a	chrIV 4,428,740	C. elegans STR-185 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	C27D6.1	C27D6.1	n/a	chrII 5,174,657	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
47	F56H6.2	F56H6.2	n/a	chrI 12,288,243	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
48	K04A8.2	K04A8.2	n/a	chrV 6,563,097	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
49	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
50	C06E4.4	C06E4.4	n/a	chrIV 7,259,079	contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)