UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cdh-7	R05H10.6	0	chrII 14,846,930	cdh-7 encodes a protein that contains a cadherin domain.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	daf-6	F31F6.5	n/a	chrX 14,891,298	daf-6 is required for an unidentified function of the nonneuronal amphidial sheath cells that promotes correct morphology of both the amphid and the outer labial sensilla; daf-6 mutants disrupt the joining of the amphid sheath and socket cells to form the receptor channel, and display defects in several distinct functions including formation of dauer larvae, chemotaxis, osmotic avoidance, male mating, negative regulation of lifespan, negative regulation of ASJ's axonal growth late in development, and dye uptake by amphids and phasmids; daf-6 has recently been reported to be identical to the coding sequence ptr-7/F31F6.5, but this assertion has not yet been verified by transgenic rescue.
4	T20D4.3	T20D4.3	n/a	chrV 3,420,496	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
5	R05C11.3	R05C11.3	n/a	chrIV 2,087,977	R05C11.3 encodes a calcium-transporting ATPase; large-scale RNAi screens indicate that R05C11.3 activity is required for locomotion and normal rates of postembryonic growth.
6	nas-15	T04G9.2	n/a	chrX 779,117	nas-15 encodes an astacin-like metalloprotease.
7	F40F4.6	F40F4.6	n/a	chrX 3,239,686	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR016187 (C-type lectin fold), IPR001881 (EGF-like calcium-binding), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR013111 (EGF, extracellular), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans), IPR002035 (von Willebrand factor, type A)
8	F52G2.3	F52G2.3	n/a	chrIV 13,545,784	contains similarity to Pfam domain PF07547 RSD-2 N-terminal domain contains similarity to Interpro domain IPR011508 (RSD-2, N-terminal)
9	C24G7.2	C24G7.2	n/a	chrI 4,105,880	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
10	M02D8.1	M02D8.1	n/a	chrX 8,765,033	contains similarity to Pfam domain PF07679 Immunoglobulin I-set domain contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR013098 (Immunoglobulin I-set), IPR013783 (Immunoglobulin-like fold), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype)
11	C27C7.2	C27C7.2	n/a	chrI 11,433,261	contains similarity to Pfam domain PF01697 (Domain of unknown function)
12	tag-198	F09G8.2	n/a	chrIII 8,269,509	C. elegans TAG-198 protein; contains similarity to Pfam domain PF03265 Deoxyribonuclease II contains similarity to Interpro domain IPR004947 (Deoxyribonuclease II)
13	tli-1	F25H2.1	n/a	chrI 10,536,634	C. elegans TLI-1 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF02845 (CUE domain) contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
14	cyp-37A1	F01D5.9	n/a	chrII 14,015,298	C. elegans CYP-37A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
15	gsnl-1	K06A4.3	n/a	chrV 9,498,184	C. elegans GSNL-1 protein; contains similarity to Pfam domain PF00626 Gelsolin repeat contains similarity to Interpro domains IPR007122 (Gelsolin), IPR007123 (Gelsolin region)
16	Y37D8A.2	Y37D8A.2	n/a	chrIII 12,822,776	contains similarity to Pfam domain PF04916 Phospholipase B contains similarity to Interpro domains IPR007000 (Laminin A), IPR013032 (EGF-like region, conserved site)
17	T14G11.3	T14G11.3	n/a	chrX 2,684,999	contains similarity to Homo sapiens inner membrane protein, mitochondrial isoform 2; ENSEMBL:ENSP00000366526
18	T01C8.5	T01C8.5	n/a	chrX 16,792,168	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
19	W03G11.3	W03G11.3	n/a	chrX 12,101,925	contains similarity to Pfam domain PF01120 Alpha-L-fucosidase contains similarity to Interpro domains IPR016286 (Alpha-L-fucosidase), IPR017853 (Glycoside hydrolase, catalytic core), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR000933 (Glycoside hydrolase, family 29 (alpha-L-fucosidase))
20	Y17G7B.11	Y17G7B.11	n/a	chrII 12,061,387	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
21	xrn-1	Y39G8C.1	n/a	chrII 14,076,171	xrn-1 encodes a 5'-3' exoribonuclease that is orthologous to Saccharomyces cerevisiae Xrnp1, a key component of the yeast 5'-3' mRNA degradation pathway; in C. elegans, XRN-1 activity is required during embryogenesis for completion of ventral enclosure, the morphogenetic process whereby the ventral epithelial cells cover and seal the interior cells of the embryo; in addition, XRN-1 also plays a role in facilitating RNA interference (RNAi), likely acting in the same pathway as the DCR-1/Dicer ribonuclease; to date, XRN-1 expression has been reported in adult hypodermal and rectal cells.
22	K02B12.3	K02B12.3	n/a	chrI 8,510,282	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
23	app-1	W03G9.4	n/a	chrI 4,965,983	C. elegans APP-1 protein; contains similarity to Pfam domains PF01321 (Creatinase/Prolidase N-terminal domain) , PF00557 (metallopeptidase family M24) contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR000587 (Creatinase)
24	F43G9.1	F43G9.1	n/a	chrI 8,607,769	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004434 (Isocitrate dehydrogenase NAD-dependent, mitochondrial), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
25	F19C7.1	F19C7.1	n/a	chrIV 4,606,991	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
26	F42A10.3	F42A10.3	n/a	chrIII 6,156,244	contains similarity to Pfam domain PF01234 NNMT/PNMT/TEMT family contains similarity to Interpro domain IPR000940 (Methyltransferase, NNMT/PNMT/TEMT)
27	F55E10.6	F55E10.6	n/a	chrX 8,345,470	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
28	lst-2	R160.7	n/a	chrX 4,380,673	C. elegans LST-2 protein; contains similarity to Pfam domain PF01363 FYVE zinc finger contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
29	glr-4	C06A8.9	n/a	chrII 7,789,680	glr-4 encodes a putative non-NMDA ionotropic glutamate receptor subunit, most closely related to GLR-3 and less so to GLR-7, possibly of the kainate subfamily; glr-4 is expressed in various sensory neurons and interneurons from embyrogenesis onward; glr-4 expression requires UNC-42, as well as CFI-1 in URA cells.
30	K02C4.2	K02C4.2	n/a	chrII 8,076,226	contains similarity to Brugia pahangi Alt-1 protein.; TR:O96781
31	R06A4.8	R06A4.8	n/a	chrII 14,354,036	R06A4.8 is orthologous to the human gene GLYCOGEN DEBRANCHING ENZYME ISOFORM 6 (AGL; OMIM:232400), which when mutated leads to glycogen storage disease, type III.
32	F35H10.10	F35H10.10	n/a	chrIV 8,310,117	contains similarity to Pfam domain PF00003 7 transmembrane receptor (metabotropic glutamate family) contains similarity to Interpro domain IPR000337 (GPCR, family 3)
33	prp-8	C50C3.6	n/a	chrIII 8,168,465	prp-8 is orthologous to the human gene SIMILAR TO U5 SNRNP-SPECIFIC PROTEIN (220 KD), ORTHOLOG OF S.
34	B0238.10	B0238.10	n/a	chrV 5,274,794	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
35	grsp-4	F07C4.7	n/a	chrV 7,625,659	C. elegans GRSP-4 protein; contains similarity to Interpro domains IPR000217 (Tubulin), IPR002952 (Eggshell protein), IPR000817 (Prion protein)
36	F08A8.3	F08A8.3	n/a	chrI 12,948,957	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
37	B0454.6	B0454.6	n/a	chrII 3,034,446	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
38	abu-1	AC3.3	n/a	chrV 10,381,053	abu-1 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-1 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-1 may help protect the organism from damage by improperly folded nascent protein.
39	far-8	K02F3.3	n/a	chrIII 843,359	C. elegans FAR-8 protein ;
40	pcca-1	F27D9.5	n/a	chrX 7,659,204	The F27D9.5 gene encodes an ortholog of the human gene PROPIONYL-COA CARBOXYLASE ALPHA SUBUNIT (PCCA), which when mutated leads to propionicaciduria, type I (OMIM:232000).
41	F40A3.6	F40A3.6	n/a	chrV 7,893,039
42	K08D10.10	K08D10.10	n/a	chrIV 4,155,758
43	arf-6	Y116A8C.12	n/a	chrIV 16,948,252	arf-6 encodes a small GTP-binding protein of the ADP-ribosylation factor (ARF) family that is orthologous to vertebrate ARF6; by homology, ARF-6 is predicted to function as a GTPase that regulates receptor-mediated endocytosis, and in C. elegans, ARF-6 is strongly expressed in the coelomocytes (highly endocytic cells located in the pseudocoelom) where it colocalizes in the cytoplasm and to a lesser degree at the plasma membrane with RME-1, a novel EH domain protein, and the myotubularins MTM-6 and MTM-9; loss of arf-6 activity via RNAi does not result in any obvious abnormalities.
44	T16G1.2	T16G1.2	n/a	chrV 12,931,137	contains similarity to Interpro domain IPR000694 (Proline-rich region)
45	cyc-1	C54G4.8	n/a	chrI 8,023,821	cyc-1 encodes a component of complex III ( cytochrome c reductase) required for normal ATP production; reduction of ATP production by cyc-1(RNAi) decreases growth rate and body size, slows behavior, and increases lifespan; cyc-1 encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial
46	K02F3.10	K02F3.10	n/a	chrIII 851,885	contains similarity to Interpro domain IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site)
47	C34H4.1	C34H4.1	n/a	chrIV 1,556,565	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
48	pmp-1	C44B7.8	n/a	chrII 6,882,170	pmp-1 encodes an ATP-binding cassette (ABC) transporter most closely related to the peroxisomal membrane proteins; pmp-1 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1.
49	ncr-1	F02E8.6	n/a	chrX 4,476,155	ncr-1 encodes a large transmembrane glycoprotein with a patched-like domain that is orthologous to human NPC1 (OMIM:257220, mutated in Niemann-Pick type C disease); NCR-1 and NPC1 are eukaryotic members of the resistance-nodulation-division (RND) family of membrane permeases, and have a putative sterol-sensing domain; by homology, NCR-1 is predicted to function in intracellular cholesterol and glycolipid trafficking; in C. elegans, NCR-1 is required for growth and survival in the absence of cholesterol, newly hatched ncr-1 mutant larvae grow poorly on cholesterol-free medium and die at the L1 or L2 stage; NCR-1 is also involved in negative regulation of dauer formation, being required redundantly with NCR-2, a second C. elegans NPC1-like protein, for preventing constitutive dauer formation; dauer formation in ncr-1; ncr-2 double mutants is suppressed by mutations in daf-12, which encodes a steroid hormone receptor, and by overexpression of daf-9, which encodes a cytochrome P450, suggesting that NCR-1 and NCR-2 may function to transport a sterol precursor that is metabolized by DAF-9 to then serve as the DAF-12 ligand.
50	W10G11.19	W10G11.19	n/a	chrII 3,552,038	contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR000886 (Endoplasmic reticulum, targeting sequence)