UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R05D3.2	R05D3.2	0	chrIII 8,373,629	R05D3.2 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:16889) (C7orf2; OMIM:605522), which when mutated leads to disease.
2	T10E9.2	T10E9.2	n/a	chrI 6,543,527
3	T19B4.5	T19B4.5	n/a	chrI 5,675,326
4	R05D11.5	R05D11.5	n/a	chrI 8,592,502	contains similarity to Pfam domain PF05620 Protein of unknown function (DUF788) contains similarity to Interpro domain IPR008506 (Protein of unknown function DUF788)
5	tag-246	ZK1128.5	n/a	chrIII 10,121,745	ZK1128.5/tag-246 encodes an ortholog of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D (SMARCD) proteins; ZK1128.5/TAG-246 is required for full levels of LIN-3/EGF signalling during vulval development, though this effect is only visible in genetically sensitized backgrounds.
6	cyn-11	T01B7.4	n/a	chrII 8,715,669	cyn-11 encodes a divergent cyclophilin D isoform, with alterations in the normally well-conserved cyclophilin-binding domain, and a central 7-8 residue insert not usually found in cyclophilins, except from plants; CYN-11 has sluggish but detectable peptidyl-prolyl isomerase activity in vitro, suggesting that it has a specialized substrate in vivo; CYN-11 is dispensable for viability and gross morphology in mass RNAi screens.
7	tag-235	M03C11.4	n/a	chrIII 10,406,358	C. elegans TAG-235 protein; contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
8	fbxb-2	T26H2.3	n/a	chrV 19,236,658	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
9	F52C9.7	F52C9.7	n/a	chrIII 5,309,798	contains similarity to Interpro domain IPR002226 (Catalase)
10	Y54E2A.12	Y54E2A.12	n/a	chrII 14,799,590	contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
11	str-226	C07G3.4	n/a	chrV 3,513,510	C. elegans STR-226 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	F59E12.1	F59E12.1	n/a	chrII 5,655,915	contains similarity to Pfam domain PF00439 Bromodomain contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001487 (Bromodomain)
13	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
14	mat-3	F10C5.1	n/a	chrIII 478,879	mat-3 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of CDC23/APC8, a conserved regulatory subunit of the anaphase-promoting complex; mat-3 activity is required for progression through metaphase of oocyte meiosis I, germline proliferation, and vulval development.
15	sas-4	F10E9.8	n/a	chrIII 8,316,386	sas-4 encodes a predicted coiled-coil protein and centriole component recruited to the centrosome once per cell cycle at the time of organelle duplication and is required for centriole duplication and spindle assembly, levels dictate centrosome size, and also affects germ cell proliferation and locomotion; colocalizes with gamma-tubulin to centrosomes both in sperm and in the syncitial part of the gonad.
16	fem-2	T19C3.8	n/a	chrIII 633,323	A CB5161 ortholog of fem-2, Cbn-fem-2, has been isolated from the sibling Caenorhabditis species CB5161.
17	T16G12.6	T16G12.6	n/a	chrIII 10,072,699	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
18	F17A9.2	F17A9.2	n/a	chrV 6,111,285	contains similarity to Pfam domains PF04676 (Protein similar to CwfJ C-terminus 2) , PF04677 (Protein similar to CwfJ C-terminus 1) contains similarity to Interpro domains IPR006768 (Protein similar to CwfJ, C-terminal 1), IPR006767 (Protein similar to CwfJ, C-terminal 2), IPR011146 (Histidine triad-like motif)
19	bag-1	F57B10.11	n/a	chrI 6,564,081	A homolog of the human BAG-family of co-chaperone proteins, negatively regulates Hsp70 and affects cell stress and cell growth.
20	T05D4.3	T05D4.3	n/a	chrIII 13,568,545	contains similarity to Interpro domain IPR005838 (Type III secretion system inner membrane P protein)
21	T24C4.7	T24C4.7	n/a	chrIII 893,471	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold), IPR007087 (Zinc finger, C2H2-type)
22	smc-4	F35G12.8	n/a	chrIII 4,590,281	The smc-4 gene encodes a homolog of the SMC4 subunit of mitotic condensin; SMC-4 acts with MIX-1 to enable chromosome segregation.
23	ugt-60	C07A9.6	n/a	chrIII 9,677,585	C. elegans UGT-60 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
24	F15H10.7	F15H10.7	n/a	chrV 10,404,755	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
25	F29G6.2	F29G6.2	n/a	chrX 11,510,328	contains similarity to Homo sapiens cDNA FLJ43363 fis, clone NT2RP7017474; ENSEMBL:ENSP00000374260
26	K02E7.2	K02E7.2	n/a	chrII 1,080,452
27	rab-10	T23H2.5	n/a	chrI 6,457,920	rab-10 encodes a Rab-like GTPase that is a member of the Ras superfamily of small GTPases; rab-10 activity is required, upstream of rme-1, for basolateral endocytic recycling in the intestine, but not in oocytes or coelomocytes; a RAB-10::GFP fusion protein is widely expressed and in the intestine, localizes to endosomes and the Golgi.
28	C09G9.2	C09G9.2	n/a	chrIV 8,868,853	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
29	T24A6.17	T24A6.17	n/a	chrV 3,564,846
30	C14C6.3	C14C6.3	n/a	chrV 544,415
31	str-223	F49C5.6	n/a	chrII 12,564,977	C. elegans STR-223 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	C01G6.3	C01G6.3	n/a	chrII 9,270,502	contains similarity to Pichia etchellsii Hypothetical protein.; TR:Q9HFH3
33	F19F10.10	F19F10.10	n/a	chrV 7,579,007	F19F10.10 encodes a protein with a THAP or THAP-like domain; other proteins with such domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
34	F16A11.1	F16A11.1	n/a	chrI 9,398,979	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001870 (B302, (SPRY)-like), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003877 (SPla/RYanodine receptor SPRY)
35	T07C4.10	T07C4.10	n/a	chrIII 10,323,248	contains similarity to Interpro domains IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
36	F28H6.4	F28H6.4	n/a	chrX 14,130,605	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR012287 (Homeodomain-related), IPR009057 (Homeodomain-like)
37	F46F11.6	F46F11.6	n/a	chrI 5,617,576	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
38	odr-7	T18D3.2	n/a	chrX 12,460,277	odr-7 encodes an olfactory-specific member of the nuclear receptor superfamily that affects chemotaxis to some volatile odorants and the cell fate of the AWA olfactory neurons; ODR-7 is expressed in the AWA neurons; in specifying the identity of the AWA neurons, ODR-7 appears to lie upstream of odr-10, which encodes a seven transmembrane domain olfactory receptor that is required for the response to diacetyl, an odorant detected by the AWA neurons.
39	C55A6.9	C55A6.9	n/a	chrV 11,522,512	contains similarity to Pfam domain PF03985 Paf1 contains similarity to Interpro domain IPR007133 (RNA polymerase II-associated, Paf1)
40	ZK1067.2	ZK1067.2	n/a	chrII 9,218,954	contains similarity to Pfam domain PF01422 NF-X1 type zinc finger contains similarity to Interpro domains IPR000967 (Zinc finger, NF-X1-type), IPR000694 (Proline-rich region), IPR001555 (Phosphoribosylglycinamide formyltransferase, active site), IPR000169 (Peptidase, cysteine peptidase active site)
41	nhr-9	ZK418.1	n/a	chrIII 7,096,245	C. elegans NHR-9 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
42	del-3	F26A3.6	n/a	chrI 7,671,514	C. elegans DEL-3 protein ;
43	C27H6.3	C27H6.3	n/a	chrV 9,981,996	contains similarity to Homo sapiens Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E; ENSEMBL:ENSP00000358111
44	spr-1	D1014.8	n/a	chrV 8,128,020	spr-1 encodes the C. elegans ortholog of the human corepressor CoREST that functions in HDAC-containing complexes to mediate transcriptional repression; in C. elegans, spr-1 was first identified in screens for genetic suppressors of the egg-laying defective phenotype of sel-12/presenilin mutants; subsequent genetic analyses showed that spr-1 likely functions as a negative regulator of LIN-12/Notch signaling in multiple cells, including those of the somatic gonad, vulva, and early embryo; spr-1 also interacts genetically with sem-5 to regulate postembryonic growth rates and lin-35Rb to regulate vulval morphogenesis and germline proliferation; in binding assays and yeast two-hybrid experiments, SPR-1 interacts with SPR-5, the C. elegans ortholog of the LSD1 histone demethylase; an SPR-1::MYC fusion protein expressed under the control of the cog-2 promoter localizes to the nucleus and shows increased staining in nuclear speckles and what appears to be the nucleolus.
45	T21C9.1	T21C9.1	n/a	chrV 10,577,614	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
46	coh-3	F08H9.1	n/a	chrV 14,458,664	coh-3 encodes a member of the Rad21/Rec8-like family of cohesion proteins that is expressed in the germline; an effect on embryonic viability has been reported based on some RNAi screens, but has not been demonstrated in others.
47	T12A2.6	T12A2.6	n/a	chrIII 6,243,060
48	F10G2.2	F10G2.2	n/a	chrV 7,331,479
49	F26A3.7	F26A3.7	n/a	chrI 7,675,432	contains similarity to Gallus gallus Putative uncharacterized protein.; TR:Q5ZIQ9
50	srt-17	F48G7.6	n/a	chrV 624,474	C. elegans SRT-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)