UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R05A10.7	R05A10.7	3.9999999999999996e-172	chrIV 14,161,499	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
2	T25B6.4	T25B6.4	n/a	chrX 9,016,157
3	T22B7.4	T22B7.4	n/a	chrX 5,639,932	contains similarity to Pfam domain PF07039 Protein of unknown function (DUF1325) contains similarity to Interpro domain IPR010750 (Protein of unknown function DUF1325)
4	T06C12.9	T06C12.9	n/a	chrV 15,885,834	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
5	Y106G6G.2	Y106G6G.2	n/a	chrI 10,325,764	contains similarity to Interpro domain IPR000904 (SEC7-like)
6	lgc-42	Y39A3B.2	n/a	chrIII 2,000,367	C. elegans LGC-42 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
7	mps-3	T06A4.2	n/a	chrI 761,378	mps-3 encodes a single-pass transmembrane protein that is related to the vertebrate KCNE proteins, also known as MinK-related peptides (MiRPs) that associate with, and regulate, pore-forming ion channels; mps-1 is required for the normal function of several neurons and thus for normal body touch sensation, chemotaxis to select molecules, osmotic avoidance, and nose-touch; when coexpressed in tissue culture cells with C. elegans KVS-1, MPS-3 is able to alter the activity of this potassium-selective channel, suggesting that MPS-3 functions in vivo to regulate KVS-1 activity in neurons in which the two proteins are coexpressed; in addition, activity of MPS-2, MPS-3, and KVS-1 coexpressed in culture suggests that these three proteins can form a functional ternary complex that genetic analyses indicate likely plays a role in regulating responsiveness to sodium; MPS-3 reporter fusions are expressed in the ADF amphid sensory neuron, the PVC and PVN neurons, and two neurons in the anterior bulb of the pharynx.
8	Y6B3B.7	Y6B3B.7	n/a	chrI 13,748,017	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
9	srh-22	C02E7.4	n/a	chrV 4,923,929	C. elegans SRH-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	kin-31	B0523.1	n/a	chrIII 8,672,572	kin-31 encodes a predicted tyrosine protein kinase expressed in the nucleus and cytoplasm of body-wall muscle cells; the expression of kin-31 was experimentally verified by RT-PCR.
11	F53F4.2	F53F4.2	n/a	chrV 13,589,230	contains similarity to Hordeum vulgare Glycine-rich cell wall structural protein precursor.; SW:P17816
12	F45C12.1	F45C12.1	n/a	chrII 1,740,047	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domains IPR000494 (EGF receptor, L domain), IPR007087 (Zinc finger, C2H2-type)
13	F58B4.4	F58B4.4	n/a	chrV 10,931,009	contains similarity to Plasmodium yoelii Rhoptry protein.; TR:Q26216
14	F19B6.3	F19B6.3	n/a	chrIV 12,327,905	contains similarity to Lactococcus lactis Unknown protein.; TR:Q9CF64
15	Y113G7B.15	Y113G7B.15	n/a	chrV 20,226,741	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
16	C50D2.6	C50D2.6	n/a	chrII 86,096
17	C34G6.3	C34G6.3	n/a	chrI 5,897,020	contains similarity to Interpro domain IPR005819 (Histone H5)
18	ZK418.6	ZK418.6	n/a	chrIII 7,076,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000694 (Proline-rich region), IPR000276 (GPCR, rhodopsin-like)
19	spe-19	Y113G7A.10	n/a	chrV 20,039,581	C. elegans SPE-19 protein ;
20	F58E6.1	F58E6.1	n/a	chrV 9,742,698	n/a
21	nhr-39	F44A2.4	n/a	chrV 9,303,947	C. elegans NHR-39 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	Y49A3A.4	Y49A3A.4	n/a	chrV 14,357,603	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
23	C45G9.11	C45G9.11	n/a	chrIII 5,066,320
24	sro-1	D1022.6	n/a	chrII 7,461,799	C. elegans SRO-1 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
25	C37C3.11	C37C3.11	n/a	chrV 7,864,144
26	C43F9.5	C43F9.5	n/a	chrIV 10,590,044	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
27	psa-1	Y113G7B.23	n/a	chrV 20,239,752	psa-1 encodes an ortholog of SWI3, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-1 is probably required during mitosis of the T cells for asymmetric cell division, and in addition, is required for embryonic and larval development, as well as normal levels of fertility; psa-1 exhibits strong genetic interactions with lin-35/Rb, as psa-1 larval lethality and sterility at 20 degrees C are greatly enhanced in lin-35;psa-1 double mutants.
28	flp-17	C52D10.11	n/a	chrIV 17,191,022	C. elegans FLP-17 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
29	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
30	fbxa-110	Y102A5C.8	n/a	chrV 16,937,848	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
31	Y43F8A.1	Y43F8A.1	n/a	chrV 19,370,930	contains similarity to Rhizobium sp Probable conjugal transfer protein trbD.; SW:TRBD_RHISN
32	M195.4	M195.4	n/a	chrII 8,376,915	contains similarity to Homo sapiens Putative uncharacterized protein (Fragment); ENSEMBL:ENSP00000333119
33	fbxa-223	ZC513.10	n/a	chrV 8,064,176	fbxa-223 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXA-223 also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
34	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
35	W03B1.8	W03B1.8	n/a	chrIV 4,344,287	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
36	cwp-5	F48C11.2	n/a	chrX 13,184,746	C. elegans CWP-5 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	sru-27	C38C3.2	n/a	chrV 1,500,054	C. elegans SRU-27 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
38	cyp-33C6	F41B5.7	n/a	chrV 2,248,474	C. elegans CYP-33C6 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
39	C35E7.6	C35E7.6	n/a	chrI 10,818,223
40	H28G03.3	H28G03.3	n/a	chrX 5,221,191
41	F35D2.4	F35D2.4	n/a	chrII 7,581,981	contains similarity to Interpro domain IPR009030 (Growth factor, receptor)
42	W03A5.2	W03A5.2	n/a	chrIII 5,407,000	W03A5.2 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:19580) (GGCX; OMIM:137167), which when mutated leads to disease.
43	F54B11.9	F54B11.9	n/a	chrX 13,607,737	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5W3
44	F10E7.9	F10E7.9	n/a	chrII 7,108,173	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domain IPR004841 (Amino acid permease-associated region)
45	Y56A3A.9	Y56A3A.9	n/a	chrIII 11,884,269	contains similarity to Interpro domains IPR015706 (RNA-directed DNA polymerase (reverse transcriptase), related), IPR000694 (Proline-rich region)
46	C12D5.9	C12D5.9	n/a	chrV 7,689,147	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
47	Y69H2.11	Y69H2.11	n/a	chrV 18,644,329	contains similarity to Pfam domains PF00008 (EGF-like domain) (6), PF00858 (Amiloride-sensitive sodium channel) contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR001873 (Na+ channel, amiloride-sensitive)
48	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
49	srz-10	ZK1037.11	n/a	chrV 15,308,296	C. elegans SRZ-10 protein ;
50	F36D1.6	F36D1.6	n/a	chrI 11,270,696	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)