UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ger-1	R01H2.5	8e-178	chrIII 7,066,371	C. elegans GER-1 protein; contains similarity to Pfam domain PF01370 NAD dependent epimerase/dehydratase family contains similarity to Interpro domains IPR001509 (NAD-dependent epimerase/dehydratase), IPR002347 (Glucose/ribitol dehydrogenase), IPR016040 (NAD(P)-binding)
2	clh-5	C07H4.2	n/a	chrII 9,096,575	The clh-5 gene encodes a chloride channel, whose human homologs include CLC1 and CLCN5; the latter homolog is imvolved in receptor-mediated endocytosis.
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	B0261.1	B0261.1	n/a	chrI 5,266,041	contains similarity to Pfam domain PF00249 Myb-like DNA-binding domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR014778 (Myb, DNA-binding), IPR009057 (Homeodomain-like)
5	Y8A9A.3	Y8A9A.3	n/a	chrII 3,791,812	contains similarity to Interpro domain IPR009071 (High mobility group box, HMG)
6	sdc-3	C25D7.3	n/a	chrV 15,043,550	sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex.
7	ncbp-1	F37E3.1	n/a	chrI 6,423,903	F37E3.1 encodes a putative nuclear cap-binding complex subunit ('CBP80') orthologous to budding yeast STO1 and human NCBP1 (OMIM:600469); in RNAi assays, F37E3.1 is required for embryonic and vulval development, normal locomotion, and general viability; by orthology to NCBP1, F37E3.1 is expected to participate in nonsense-mediated mRNA decay via a pioneer round of translation; F37E3.1(RNAi) induces expression of a gpdh-1::GFP transgene, perhaps because F37E3.1 prevents protein misfolding.
8	Y37E11B.5	Y37E11B.5	n/a	chrIV 3,596,256	contains similarity to Pfam domains PF01207 (Dihydrouridine synthase (Dus)) , PF00642 (Zinc finger C-x8-C-x5-C-x3-H type (and similar)) (2)contains similarity to Interpro domains IPR000571 (Zinc finger, CCCH-type), IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
9	glt-6	R05G6.6	n/a	chrIV 7,505,011	glt-6 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
10	T08D2.1	T08D2.1	n/a	chrX 162,831	contains similarity to Pfam domain PF01105 emp24/gp25L/p24 family/GOLD contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR009038 (GOLD), IPR000348 (emp24/gp25L/p24)
11	Y47H9C.8	Y47H9C.8	n/a	chrI 11,895,073	contains similarity to Streptococcus pneumoniae Magnesium transporter, CorA family.; TR:Q97SX8
12	F20D1.2	F20D1.2	n/a	chrX 14,972,677	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR000195 (RabGAP/TBC)
13	mep-1	M04B2.1	n/a	chrIV 11,526,270	mep-1 is required for repression by the fem-3 3' UTR in vivo, and for maintenance of somatic (versus germline) differentiation; MEP-1 protein has zinc-finger domains and a glutamine/asparagine-rich domain.
14	npp-11	F53F10.5	n/a	chrI 3,819,703	C. elegans NPP-11 protein; contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
15	T07G12.8	T07G12.8	n/a	chrIV 10,553,796	contains similarity to Thermoplasma volcanium ABC transport system permease protein P1P2A1A2.; TR:Q978R0
16	C49H3.8	C49H3.8	n/a	chrIV 7,901,218	contains similarity to Pfam domain PF00022 Actin contains similarity to Interpro domains IPR001478 (PDZ/DHR/GLGF), IPR004000 (Actin/actin-like), IPR013126 (Heat shock protein 70)
17	F17A9.3	F17A9.3	n/a	chrV 6,106,582	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
18	tag-72	C25A1.3	n/a	chrI 10,160,921	C. elegans TAG-72 protein; contains similarity to Pfam domains PF03291 (mRNA capping enzyme) , PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR004971 (mRNA capping enzyme, large subunit), IPR016899 (mRNA (guanine-N(7))-methyltransferase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
19	F22B5.10	F22B5.10	n/a	chrII 8,467,514	contains similarity to Pfam domain PF05809 Eukaryotic protein of unknown function (DUF841) contains similarity to Interpro domain IPR008559 (Protein of unknown function DUF841, eukaryotic)
20	T10D4.6	T10D4.6	n/a	chrII 3,121,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR009057 (Homeodomain-like)
21	F16B12.6	F16B12.6	n/a	chrX 14,105,057	contains similarity to Mus musculus Neurofilament triplet H protein (200 kDa neurofilament protein)s(Neurofilament heavy polypeptide) (NF-H).; SW:NFH_MOUSE
22	F46H5.4	F46H5.4	n/a	chrX 7,249,770	contains similarity to Pfam domain PF06920 Dedicator of cytokinesis contains similarity to Interpro domains IPR011608 (PRD), IPR002052 (N-6 adenine-specific DNA methylase, conserved site), IPR010703 (Dedicator of cytokinesis), IPR016024 (Armadillo-type fold), IPR000008 (C2 calcium-dependent membrane targeting)
23	F09E10.5	F09E10.5	n/a	chrX 1,492,033
24	F47G9.1	F47G9.1	n/a	chrV 11,325,591	contains similarity to Interpro domain IPR009038 (GOLD)
25	T08A11.2	T08A11.2	n/a	chrIII 4,266,506	T08A11.2 encodes the C. elegans ortholog of splicing factor 3b subunit 1, also known as SAP155; by homology, the product of T08A11.2 is predicted to be a component of the U2 snRNP that is required for pre-mRNA splicing; large-scale RNAi assays indicate that T08A11.2 activity is essential for a number of processes including embryonic development, normal adult lifespan, vulval morphogenesis, locomotion, and transgene expression and localization.
26	tag-135	D1054.15	n/a	chrV 10,807,021	C. elegans TAG-135 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR009146 (Groucho/transducin-like enhancer), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
27	C06E1.3	C06E1.3	n/a	chrIII 8,582,414	contains similarity to Drosophila melanogaster Flybase gene name is mol-PD;; FLYBASE:CG4482
28	pqn-20	C37A2.2	n/a	chrI 6,794,248	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
29	W09G10.3	W09G10.3	n/a	chrII 3,526,838	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
30	sre-27	Y57A10C.3	n/a	chrII 12,416,469	C. elegans SRE-27 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
31	C47E12.3	C47E12.3	n/a	chrIV 10,000,452	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
32	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
33	dpy-26	C25G4.5	n/a	chrIV 12,448,610	dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array.
34	F21H12.1	F21H12.1	n/a	chrII 6,098,704	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
35	ZK1321.1	ZK1321.1	n/a	chrII 9,754,525	contains similarity to Sulfolobus sp NOB8H2 Hypothetical protein.; TR:O93705
36	F23C8.9	F23C8.9	n/a	chrI 2,433,103	contains similarity to Pfam domain PF07962 Replication Fork Protection Component Swi3 contains similarity to Interpro domain IPR012923 (Replication fork protection component Swi3)
37	F33H2.5	F33H2.5	n/a	chrI 15,009,733	contains similarity to Pfam domains PF00136 (DNA polymerase family B) , PF03104 (DNA polymerase family B, exonuclease domain) , PF08490 (Domain of unknown function (DUF1744)) contains similarity to Interpro domains IPR006055 (Exonuclease), IPR006172 (DNA-directed DNA polymerase, family B), IPR006133 (DNA-directed DNA polymerase, family B, exonuclease), IPR006134 (DNA-directed DNA polymerase, family B, conserved region), IPR013697 (Region of unknown function DUF1744), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
38	cin-4	ZK1127.7	n/a	chrII 7,039,709	C. elegans CIN-4 protein
39	K01A11.3	K01A11.3	n/a	chrIII 3,450,547	contains similarity to Pfam domain PF00443 (Ubiquitin carboxyl-terminal hydrolases family 2)
40	Y45G12B.3	Y45G12B.3	n/a	chrV 2,691,488	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
41	F56D2.3	F56D2.3	n/a	chrIII 5,585,825
42	snr-2	W08E3.1	n/a	chrI 13,339,794	C. elegans SNR-2 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core)
43	rad-26	C27B7.4	n/a	chrIV 8,897,727	C. elegans RAD-26 protein; contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR000694 (Proline-rich region), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal), IPR000276 (GPCR, rhodopsin-like)
44	Y45F10D.7	Y45F10D.7	n/a	chrIV 13,792,547	Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA.
45	M03C11.3	M03C11.3	n/a	chrIII 10,409,775	contains similarity to Saccharomyces cerevisiae Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; SGD:YKL172W
46	fipr-15	F13E9.3	n/a	chrIV 10,880,611	C. elegans FIPR-15 protein; contains similarity to Interpro domain IPR005137 (Photosystem I assembly BtpA)
47	eif-3.H	C41D11.2	n/a	chrI 4,445,653	C. elegans EIF-3.H protein; contains similarity to Pfam domain PF01398 Mov34/MPN/PAD-1 family contains similarity to Interpro domains IPR000555 (Mov34/MPN/PAD-1), IPR003639 (Mov34-1)
48	T22C1.6	T22C1.6	n/a	chrI 7,944,147	contains similarity to Homo sapiens Alpha-taxilin; ENSEMBL:ENSP00000362711
49	ZK632.7	ZK632.7	n/a	chrIII 9,821,105	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
50	C25G4.3	C25G4.3	n/a	chrIV 12,445,137	contains similarity to Pfam domain PF02033 Ribosome-binding factor A contains similarity to Interpro domains IPR000238 (Ribosome-binding factor A), IPR015946 (K homology-like, alpha/beta)