UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R01E6.7	R01E6.7	4e-152	chrX 13,568,618	contains similarity to Ectocarpus siliculosus virus EsV-1-142.; TR:Q8QKY0
2	unc-9	R12H7.1	n/a	chrX 13,214,484	unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.
3	K07E12.2	K07E12.2	n/a	chrIII 6,737,547
4	F46F5.4	F46F5.4	n/a	chrII 805,580	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
5	srsx-14	C39H7.5	n/a	chrIV 5,625,990	C. elegans SRSX-14 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
7	B0524.2	B0524.2	n/a	chrIII 1,896,968	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
8	abt-3	F55G11.9	n/a	chrIV 12,953,691	abt-3 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-3 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-3 activity via RNAi results in no obvious defects, the precise role of abt-3 in C. elegans development and/or behavior is not yet known.
9	T05A8.1	T05A8.1	n/a	chrII 2,709,077
10	F46F5.11	F46F5.11	n/a	chrII 810,328	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
11	C39D10.6	C39D10.6	n/a	chrX 7,896,965
12	F54H12.5	F54H12.5	n/a	chrIII 7,971,111	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
13	T19D7.5	T19D7.5	n/a	chrX 665,501
14	F40G9.14	F40G9.14	n/a	chrIII 176,962	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR007087 (Zinc finger, C2H2-type)
15	C41G7.7	C41G7.7	n/a	chrI 9,534,916	contains similarity to Plasmodium falciparum S-antigen (Fragment).; TR:Q9GZB4
16	sea-2	K10G6.3	n/a	chrII 3,966,905	sea-2 is an autosomal signal element gene, whose protein product contains four C2H2 zinc finger domains and three involucrin repeats embedded in extensive regions of low-complexity (e.g., glutamine/asparagine-rich) protein sequence; sea-2 has no obvious biological function in mass RNAi assays.
17	CD4.1	CD4.1	n/a	chrV 5,608,204
18	F26F2.4	F26F2.4	n/a	chrV 20,565,244	contains similarity to Homo sapiens Laminin alpha-4 chain precursor; ENSEMBL:ENSP00000230538
19	W03F8.2	W03F8.2	n/a	chrIV 5,191,305	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif)
20	BE10.1	BE10.1	n/a	chrIII 12,788,458	contains similarity to Homo sapiens PRO2015; TR:Q9P185
21	K09E4.2	K09E4.2	n/a	chrII 14,130,163	contains similarity to Pfam domain PF05208 ALG3 protein contains similarity to Interpro domains IPR007873 (ALG3), IPR013838 (Beta tubulin, autoregulation binding site)
22	F08D12.2	F08D12.2	n/a	chrII 2,782,368	contains similarity to Pfam domain PF04942 CC domain contains similarity to Interpro domain IPR007026 (Domian of unknown function, DUF-CC)
23	C33E10.6	C33E10.6	n/a	chrX 17,268,242	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227I5
24	C03B1.6	C03B1.6	n/a	chrX 6,350,637
25	sra-38	T21H8.3	n/a	chrX 13,898,963	C. elegans SRA-38 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
26	twk-21	T01B4.1	n/a	chrX 16,302,750	C. elegans TWK-21 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
27	W02B8.4	W02B8.4	n/a	chrII 13,922,543	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
28	F15H9.1	F15H9.1	n/a	chrI 12,157,921	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
29	C06C3.9	C06C3.9	n/a	chrII 9,377,271
30	set-19	W01C8.3	n/a	chrX 5,677,695	set-19 encodes a SET domain-containing protein; SET-19 has no non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-20, SET-21, and SET-32); neither set-19(ok1813) nor set-19(RNAi) have any obvious phenotypes.
31	Y47H9B.2	Y47H9B.2	n/a	chrI 11,745,783	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
32	Y7A5A.8	Y7A5A.8	n/a	chrX 15,823,201	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IL30
33	Y116A8C.33	Y116A8C.33	n/a	chrIV 17,113,736	contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
34	F35B3.7	F35B3.7	n/a	chrX 17,038,997	contains similarity to Homo sapiens Leucine zipper putative tumor suppressor 2; ENSEMBL:ENSP00000359240
35	F28H7.7	F28H7.7	n/a	chrV 10,752,577	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
36	ace-3	Y48B6A.8	n/a	chrII 14,207,809	ace-3 encodes one of four C. elegans acetylcholinesterases (AChE); ACE-3 represents ~5% of the total AChE activity in C. elegans and in vitro, hydrolyzes acetylthio-, butyrylthio-, and propionylthiocholine substrates with equal efficiency; although loss-of-function mutations in ace-3 result in no obvious defects, animals doubly mutant with ace-1 or ace-2 have slight defects in backward locomotion and animals triply mutant for ace-1, -2, and -3 arrest as unhatched, yet fully developed, embryos; ace-3 is the downstream gene in an operon with a fourth AChE-encoding gene, ace-4, and transcriptional reporter fusions with ace-4 upstream sequences direct expression in pharyngeal muscles pm3, 4, 5, and 7, the two CAN (canal associated neuron) cells, midbody dorsal body wall muscles in larvae, and several neurons in the head and anal ganglion
37	kcc-3	K02A2.3	n/a	chrII 7,428,601	C. elegans KCC-3 protein; contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR000076 (K-Cl co-transporter), IPR004841 (Amino acid permease-associated region)
38	F09E8.1	F09E8.1	n/a	chrIV 13,141,838	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domains IPR011052 (Proteinase and amylase inhibitor), IPR002593 (Protein of unknown function DX)
39	R04A9.1	R04A9.1	n/a	chrX 405,128
40	F54D12.7	F54D12.7	n/a	chrII 1,383,599	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
41	bath-47	T07H3.1	n/a	chrII 1,603,204	C. elegans BATH-47 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) (2), PF00917 (MATH domain) (2)contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000694 (Proline-rich region), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
42	F23H11.7	F23H11.7	n/a	chrIII 918,259
43	sng-1	T08A9.3	n/a	chrX 7,328,590	sng-1 encodes the C. elegans synaptogyrin ortholog, a vertebrate integral membrane synaptic vesicle protein; loss-of-function mutations in sng-1 result in no obvious defects in synaptogenesis or neuronal activity, suggesting that SNG-1 is likely required for more subtle neuronal functions; SNG-1::GFP reporters are expressed throughout the nervous system in neurons in the dorsal and ventral nerve cords, as well as the anterior nerve ring; SNG-1 colocalizes with the synaptic vesicle component SNT-1.
44	C38H2.1	C38H2.1	n/a	chrIII 10,369,054	contains similarity to Pfam domains PF00566 (TBC domain) , PF02759 (RUN domain) contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR004012 (RUN)
45	F02H6.6	F02H6.6	n/a	chrIV 14,230,085	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
46	C38C3.7	C38C3.7	n/a	chrV 1,502,860	contains similarity to Pfam domains PF01827 (FTH domain) (2), PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
47	srx-90	H12C20.5	n/a	chrV 11,581,770	C. elegans SRX-90 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
48	F55D10.4	F55D10.4	n/a	chrX 4,718,585
49	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
50	nhr-196	K06B4.5	n/a	chrV 15,686,814	C. elegans NHR-196 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)