UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	glb-20	R01E6.6	2e-149	chrX 13,554,276	glb-20 encodes a globin; glb-20 transcription is higher in L3 and dauers than in young adults; glb-20 has no obvious function in mass RNAi assays.
2	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
3	fbxb-21	ZC204.8	n/a	chrII 1,648,389	fbxb-21 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-21 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
4	srh-283	C47A10.2	n/a	chrV 17,766,031	C. elegans SRH-283 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
6	sdz-34	Y73C8C.7	n/a	chrV 3,108,727	C. elegans SDZ-34 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin), IPR011016 (Zinc finger, variant RING-type)
7	srt-45	M162.3	n/a	chrV 19,780,434	C. elegans SRT-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
8	C53D6.6	C53D6.6	n/a	chrIV 9,030,151	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
9	R11G11.3	R11G11.3	n/a	chrV 531,412	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
10	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	C10G11.6	C10G11.6	n/a	chrI 6,291,932
12	sra-33	B0304.6	n/a	chrII 4,535,979	C. elegans SRA-33 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
13	clec-247	Y51A2A.1	n/a	chrV 18,285,606	C. elegans CLEC-247 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
14	srg-5	T12A2.11	n/a	chrIII 6,263,078	C. elegans SRG-5 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
15	nas-21	T11F9.5	n/a	chrV 11,473,207	nas-21 encodes an astacin-like metalloprotease.
16	unc-39	F56A12.1	n/a	chrV 14,374,572	unc-39 encodes a homeodomain transcription factor that belongs to the Six4/5 family of homeodomain proteins that includes human Six5; UNC-39 is required for axonal pathfinding in anterior-derived neurons and for specification of most mesodermal cell types and may regulate a developmental decision between migration and differentiation; UNC-39 is expressed in the embryo in anterior neurons, posteriorly derived mesoderm (somatic gonad, M mesoblast, and possibly the coelomocytes and muIntR), the CAN neurons, and body wall muscle.
17	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
18	T10H10.2	T10H10.2	n/a	chrX 2,296,444	contains similarity to Pfam domains PF04777 (Erv1 / Alr family) , PF00085 (Thioredoxin) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR006863 (Erv1/Alr), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
19	srd-25	F07C4.4	n/a	chrV 7,632,583	C. elegans SRD-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	str-225	C07G3.6	n/a	chrV 3,508,534	C. elegans STR-225 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001307 (Thiosulphate sulphurtransferase, conserved site)
21	fut-2	EGAP9.2	n/a	chrV 6,574,873	fut-2 encodes a unique alpha 1,2-fucosyltransferase specifically expressed in intestinal cells of larval and adult animals; recombinant FUT-2 expressed in human 293T cells exhibits a novel acceptor specificity profile compared with mammalian alpha 1,2-fucosyltransferases and the predicted protein shares very low amino acid identity with human alpha 1,2-fucosyltransferases, but its predicted type 2 topology and domain structure are typical of other glucosyltransferases.
22	F15D4.4	F15D4.4	n/a	chrII 13,241,088	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
23	EGAP2.2	EGAP2.2	n/a	chrII 5,230,269
24	Y75B8A.14	Y75B8A.14	n/a	chrIII 12,217,589	contains similarity to Pfam domain PF03029 Conserved hypothetical ATP binding protein contains similarity to Interpro domain IPR004130 (Protein of unknown function, ATP binding)
25	K09B11.4	K09B11.4	n/a	chrIV 13,429,722	contains similarity to Patella vulgata Twist protein (Fragment).; TR:Q8WQQ8
26	C17B7.10	C17B7.10	n/a	chrV 3,341,460	C17B7.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C17B7.10 has no clear orthologs in other organisms.
27	clec-246	F16H6.2	n/a	chrV 18,190,268	C. elegans CLEC-246 protein ;
28	W01A11.2	W01A11.2	n/a	chrV 6,497,783	contains similarity to Pfam domain PF03982 Diacylglycerol acyltransferase contains similarity to Interpro domain IPR007130 (Diacylglycerol acyltransferase)
29	ZC53.4	ZC53.4	n/a	chrX 1,931,714	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227Y0
30	F38E1.11	F38E1.11	n/a	chrV 8,379,393
31	B0284.2	B0284.2	n/a	chrIII 4,382,911	contains similarity to Homo sapiens Isoform 1 of Progesterone-induced-blocking factor 1; ENSEMBL:ENSP00000317144
32	ZK353.2	ZK353.2	n/a	chrIII 8,398,849	contains similarity to Interpro domain IPR002952 (Eggshell protein)
33	F55G7.3	F55G7.3	n/a	chrX 11,941,116	contains similarity to Saccharomyces cerevisiae appears to control expression of spliceosome components PRP4 and PRP3; SGD:YDR464W
34	srj-45	T03D3.6	n/a	chrV 2,836,005	C. elegans SRJ-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR006162 (Phosphopantetheine attachment site)
35	tag-294	C54H2.3	n/a	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
36	F46B3.15	F46B3.15	n/a	chrV 20,628,725	contains similarity to Interpro domain IPR003645 (Follistatin-like, N-terminal)
37	C06E4.5	C06E4.5	n/a	chrIV 7,255,611	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
38	gcy-4	ZK970.5	n/a	chrII 10,306,418	gcy-4 encodes a predicted transmembrane guanylyl cyclase; by homology, GCY-4 may function as a chemosensory receptor; however, as loss of gcy-4 activity via mutation or large-scale RNAi screens results in no obvious abnormalities, the precise role of gcy-4 in C. elegans development and/or behavior is not yet known; the sole gcy-4 ::GFP reporter construct reported to date did not produce any specific GFP signals.
39	R05F9.7	R05F9.7	n/a	chrII 4,887,230	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
40	srj-1	ZK829.8	n/a	chrIV 11,964,638	C. elegans SRJ-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F22E12.3	F22E12.3	n/a	chrV 10,461,278	contains similarity to Petroselinum crispum Reverse transcriptase (Fragment).; TR:Q9ZRL1
42	srx-39	C03A7.6	n/a	chrV 5,157,191	C. elegans SRX-39 protein; contains similarity to Pfam domains PF00001 (7 transmembrane receptor (rhodopsin family)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
43	C08A9.8	C08A9.8	n/a	chrX 17,103,774	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
44	vab-15	R07B1.1	n/a	chrX 9,848,439	The vab-15 gene encodes a msh-like homeobox gene that appears required for production of touch cell precursors, and that is orthologous to the human gene MSH HOMEO BOX HOMOLOG 1 (MSX1; OMIM:142983) which when mutated leads to disease.
45	F01F1.14	F01F1.14	n/a	chrIII 5,882,603
46	srj-29	F22B8.1	n/a	chrV 16,076,456	C. elegans SRJ-29 protein; contains similarity to Pfam domains PF00060 (Ligand-gated ion channel) , PF01094 (Receptor family ligand binding region) contains similarity to Interpro domains IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR015683 (Glutamate receptor-related), IPR001320 (Ionotropic glutamate receptor), IPR001828 (Extracellular ligand-binding receptor), IPR001508 (NMDA receptor)
47	nhr-241	Y69H2.8	n/a	chrV 18,700,186	C. elegans NHR-241 protein
48	C37E2.3	C37E2.3	n/a	chrX 14,180,268	contains similarity to Pfam domain PF04750 FAR-17a/AIG1-like protein contains similarity to Interpro domains IPR006838 (FAR-17a/AIG1-like protein), IPR002208 (SecY protein)
49	apc-11	F35G12.9	n/a	chrIII 4,594,070	apc-11 encodes a predicted key catalytic subunit of the anaphase promoting complex that is required for embryonic development past the embryonic one- cell stage.
50	fbxa-113	Y113G7B.6	n/a	chrV 20,199,350	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.