UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	mtss-1	PAR2.1	2e-94	chrIII 8,768,640	C. elegans MTSS-1 protein; contains similarity to Pfam domain PF00436 Single-strand binding protein family contains similarity to Interpro domains IPR000424 (Primosome PriB/single-strand DNA-binding), IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR011344 (Single-strand DNA-binding)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C04C3.3	C04C3.3	n/a	chrIV 3,401,683	contains similarity to Pfam domains PF02780 (Transketolase, C-terminal domain) , PF02779 (Transketolase, pyrimidine binding domain) contains similarity to Interpro domains IPR005476 (Transketolase, C-terminal), IPR005475 (Transketolase, central region), IPR015941 (Transketolase C-terminal-like)
4	F57G8.5	F57G8.5	n/a	chrV 16,340,228	contains similarity to Pfam domain PF00999 Sodium/hydrogen exchanger family contains similarity to Interpro domain IPR006153 (Sodium/hydrogen exchanger)
5	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
6	T10D4.6	T10D4.6	n/a	chrII 3,121,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR009057 (Homeodomain-like)
7	glrx-5	Y49E10.2	n/a	chrIII 12,373,098	C. elegans GLRX-5 protein; contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR014025 (Glutaredoxin subgroup), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004480 (Glutaredoxin-related protein)
8	F44E2.3	F44E2.3	n/a	chrIII 8,828,256	contains similarity to Interpro domain IPR000694 (Proline-rich region)
9	figl-1	F32D1.1	n/a	chrV 4,343,730	F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays.
10	C49H3.8	C49H3.8	n/a	chrIV 7,901,218	contains similarity to Pfam domain PF00022 Actin contains similarity to Interpro domains IPR001478 (PDZ/DHR/GLGF), IPR004000 (Actin/actin-like), IPR013126 (Heat shock protein 70)
11	T19D7.4	T19D7.4	n/a	chrX 660,149	contains similarity to Interpro domains IPR010989 (t-SNARE), IPR004012 (RUN)
12	cif-1	K08F11.3	n/a	chrIV 4,708,690	C. elegans CIF-1 protein; contains similarity to Pfam domain PF01399 PCI domain contains similarity to Interpro domain IPR000717 (Proteasome component region PCI)
13	C05D11.10	C05D11.10	n/a	chrIII 6,431,356	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
14	ZK836.3	ZK836.3	n/a	chrV 12,195,261
15	C45E5.1	C45E5.1	n/a	chrIV 5,745,740	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
16	K09C4.5	K09C4.5	n/a	chrX 3,284,155	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
17	clh-6	R07B7.1	n/a	chrV 12,061,778	clh-6 encodes a voltage-gated chloride channel orthologous to the human CLCN7 chloride channel (OMIM:602727, which when mutated lead to osteopetrosis); although the precise role of CLH-6 in C. elegans development and/or behavior is not yet known, CLH-6 expression is detected in two GABA-ergic neurons, RMEL and RMER, suggesting that CLH-6 could play a role in membrane excitability and/or GABA packaging; as CLH-6 is also detected in many non-neuronal tissues, such as the gut and body wall muscle, it could also have a broader role in such as processes as transepithelial transport and muscle excitation.
18	C56G3.2	C56G3.2	n/a	chrX 7,365,880	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
19	C05G5.1	C05G5.1	n/a	chrX 14,737,200	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
20	W04A8.2	W04A8.2	n/a	chrI 13,840,793	contains similarity to Streptococcus pyogenes Putative type I site-specific deoxyribonuclease hsdS subunit.; TR:Q8K5V9
21	K01A11.3	K01A11.3	n/a	chrIII 3,450,547	contains similarity to Pfam domain PF00443 (Ubiquitin carboxyl-terminal hydrolases family 2)
22	F56A11.5	F56A11.5	n/a	chrIV 569,608	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR001484 (Pyrokinin, conserved site), IPR011037 (Pyruvate kinase, beta-barrel-like)
23	W04B5.4	W04B5.4	n/a	chrIII 2,408,633	W04B5.4 encodes a putative mitochondrial ribosomal protein L30 that inhibits DHC-1 in vivo; W04B5.4 is orthologous to human MRPL3; W04B5.4(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that W04B5.4 negatively regulates dynein; W04B5.4 is required for embryonic and larval development in mass RNAi assays.
24	math-40	T08E11.3	n/a	chrII 1,831,237	C. elegans MATH-40 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
25	F52C12.2	F52C12.2	n/a	chrIV 1,956,651	contains similarity to Pfam domains PF04068 (Possible metal-binding domain in RNase L inhibitor, RLI) , PF04034 (Domain of unknown function (DUF367)) contains similarity to Interpro domains IPR007209 (Possible metal-binding region in RNase L inhibitor, RLI), IPR007177 (Protein of unknown function DUF367)
26	F13E6.5	F13E6.5	n/a	chrX 10,696,500	contains similarity to Pfam domain PF01569 PAP2 superfamily contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR016118 (Phosphatidic acid phosphatase/chloroperoxidase, N-terminal)
27	Y45G12C.4	Y45G12C.4	n/a	chrV 2,547,175	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
28	cdr-6	K01D12.12	n/a	chrV 12,413,079	C. elegans CDR-6 protein; contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR010987 (Glutathione S-transferase, C-terminal-like)
29	T20H4.5	T20H4.5	n/a	chrIII 7,233,493	T20H4.5 gene encodes a 23 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation and for resistance to volatile anesthetics; T20H4.5 is orthologous to human NDUFS8 (OMIM:602141, mutated in Leigh syndrome).
30	F23F12.3	F23F12.3	n/a	chrIII 6,504,028	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
31	ncbp-1	F37E3.1	n/a	chrI 6,423,903	F37E3.1 encodes a putative nuclear cap-binding complex subunit ('CBP80') orthologous to budding yeast STO1 and human NCBP1 (OMIM:600469); in RNAi assays, F37E3.1 is required for embryonic and vulval development, normal locomotion, and general viability; by orthology to NCBP1, F37E3.1 is expected to participate in nonsense-mediated mRNA decay via a pioneer round of translation; F37E3.1(RNAi) induces expression of a gpdh-1::GFP transgene, perhaps because F37E3.1 prevents protein misfolding.
32	F22B8.6	F22B8.6	n/a	chrV 16,101,647	F22B8.6 encodes a putative cystathionine gamma-lyase; F22B8.6 is orthologous to human CTH (OMIM:607657, mutated in cystathioninuria), extremely similar to its paralog ZK1127.10, and also paralogous to C12C8.2; either F22B8.6, or ZK1236.10, or both proteins weakly inhibit DHC-1 in vivo; otherwise, F22B8.6 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with ZK1127.10.
33	C50F2.3	C50F2.3	n/a	chrI 3,878,907	contains similarity to Pfam domain PF02184 HAT (Half-A-TPR) repeat contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013212 (Mad3/BUB1 homology region 1), IPR003107 (RNA-processing protein, HAT helix)
34	B0205.6	B0205.6	n/a	chrI 10,738,293	contains similarity to Pfam domains PF01212 (Beta-eliminating lyase) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR001597 (Aromatic amino acid beta-eliminating lyase/threonine aldolase), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR016454 (Cysteine desulphurase, NifS), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
35	plc-4	R05G6.8	n/a	chrIV 7,511,060	C. elegans PLC-4 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF09279 (Phosphoinositide-specific phospholipase C, efhand-like) , PF00036 (EF hand) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR015359 (Phospholipase C, phosphoinositol-specific, EF-hand-like), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes), IPR000008 (C2 calcium-dependent membrane targeting)
36	T05F1.11	T05F1.11	n/a	chrI 9,654,690	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	eif-3.F	D2013.7	n/a	chrII 9,332,730	C. elegans EIF-3.F protein; contains similarity to Pfam domain PF01398 Mov34/MPN/PAD-1 family contains similarity to Interpro domains IPR000555 (Mov34/MPN/PAD-1), IPR003639 (Mov34-1)
38	T14B4.1	T14B4.1	n/a	chrII 6,739,132
39	Y47D3B.9	Y47D3B.9	n/a	chrIII 11,467,116	contains similarity to Pfam domain PF02892 BED zinc finger contains similarity to Interpro domain IPR003656 (Zinc finger, BED-type predicted)
40	C06H5.6	C06H5.6	n/a	chrV 17,884,381	contains similarity to Pfam domains PF00083 (Sugar (and other) transporter) , PF07690 (Major Facilitator Superfamily) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
41	C47E12.3	C47E12.3	n/a	chrIV 10,000,452	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
42	cyp-25A2	C36A4.2	n/a	chrIII 3,836,163	C. elegans CYP-25A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
43	F34H10.2	F34H10.2	n/a	chrX 9,630,584	contains similarity to Anabaena sp Hypothetical protein Alr0331.; TR:Q8YZX4
44	ttll-5	C55A6.2	n/a	chrV 11,510,749	ttll-5 encodes a putative tubulin polyglutamylase orthologous to human TTLL5; TTLL-5 is required for embryonic development and fertility; by orthology, TTLL-5 is expected to initiate glutamyl chains rather than elongating them, to prefer alpha-tubulin over beta-tubulin as a substrate, and to have non-tubulin substrates.
45	C01F1.2	C01F1.2	n/a	chrII 4,300,243	C01F1.2 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the C01F1.2 protein is predicted to be mitochondrial with 68% accuracy.
46	Y39A1A.6	Y39A1A.6	n/a	chrIII 10,616,526	contains similarity to Interpro domains IPR005727 (Ribosomal protein L22, bacterial-type), IPR001063 (Ribosomal protein L22/L17)
47	rad-26	C27B7.4	n/a	chrIV 8,897,727	C. elegans RAD-26 protein; contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR000694 (Proline-rich region), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal), IPR000276 (GPCR, rhodopsin-like)
48	dnj-15	K08D10.2	n/a	chrIV 4,177,547	This gene encodes a protein containing a DnaJ ('J') domain.
49	pqn-96	ZK1236.6	n/a	chrIII 8,438,835	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
50	seld-1	Y45F10A.4	n/a	chrIV 13,507,532	C. elegans SELD-1 protein; contains similarity to Pfam domains PF02769 (AIR synthase related protein, C-terminal domain) , PF00586 (AIR synthase related protein, N-terminal domain) contains similarity to Interpro domains IPR016188 (PurM, N-terminal-like), IPR000728 (AIR synthase related protein), IPR010918 (AIR synthase related protein, C-terminal), IPR004536 (Selenide water dikinase)