UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	flp-19	M79.4	4e-46	chrX 10,605,248	C. elegans FLP-19 protein ;
2	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
3	nlp-3	F48C11.3	n/a	chrX 13,178,076	nlp-3 encodes a neuropeptide-like protein of the GFxGF family with similarity to orcokinins, highly conserved peptides native to crustaceans that enhance hindgut contractions; NLP-3 is expressed in neurons in the head, pharynx, and vulva, and in the intestine; the precise role of NLP-3 in nervous system function and development is not yet clear.
4	nlp-1	C01C4.1	n/a	chrX 3,727,992	nlp-1 encodes a predicted neuropeptide-like protein of the MSFamide family with similarity to Aplysia californica (sea hare) buccalin, a neuropeptide that regulates acetylcholine-induced muscle contraction; NLP-1 is expressed in the phasmid PHB tail sensory neuron, lateral neurons, head neurons, and the intestine; the precise role of NLP-1 in nervous system function and development is not yet known.
5	snt-4	T23H2.2	n/a	chrI 6,438,658	C. elegans SNT-4 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
6	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
7	flp-7	F49E10.3	n/a	chrX 5,886,304	flp-7 encodes an MVRFamide-containing peptide that, upon injection into A. suum, produces paralysis and loss of locomotory waveforms, increased body length, and decreased cAMP production.
8	nlp-14	D1009.4	n/a	chrX 8,918,369	C. elegans NLP-14 protein; contains similarity to Interpro domain IPR005829 (Sugar transporter, conserved site)
9	sbt-1	T03D8.3	n/a	chrV 20,823,688	C. elegans SBT-1 protein; contains similarity to Pfam domain PF05281 Neuroendocrine protein 7B2 precursor (Secretogranin V) contains similarity to Interpro domain IPR007945 (Neuroendocrine 7B2 precursor)
10	nlp-8	D2005.2	n/a	chrI 7,801,131	C. elegans NLP-8 protein ;
11	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
12	nlp-37	F48B9.4	n/a	chrX 2,163,570	C. elegans NLP-37 protein ;
13	C17G10.7	C17G10.7	n/a	chrII 5,607,281
14	flp-3	W07E11.2	n/a	chrX 10,092,469	flp-3 encodes nine copies of a GTMRFamide-containing peptide that is predicted to function as a neuropeptide that inhibits pharyngeal action potential in a manner similar to octopamine without having a significant effect on basal resting membrane potential; expressed in three pairs of neurons IL1D, OL1, URB.
15	ins-18	T28B8.2	n/a	chrI 8,148,533	ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; ins-18::gfp reporters are expressed in neurons and the intestine.
16	F53A9.6	F53A9.6	n/a	chrX 8,713,583	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen)
17	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
18	pqn-48	K07D4.8	n/a	chrII 4,040,965	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
19	ttr-29	R90.4	n/a	chrV 12,906,429	C. elegans TTR-29 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
20	T21C12.3	T21C12.3	n/a	chrIII 10,538,504	contains similarity to Leptospira interrogans Hypothetical protein.; TR:Q8EZD2
21	F52E1.8	F52E1.8	n/a	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
22	C47D2.1	C47D2.1	n/a	chrX 8,215,243
23	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
24	ZC204.1	ZC204.1	n/a	chrII 1,666,906	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
25	ttr-23	T21C9.8	n/a	chrV 10,589,462	C. elegans TTR-23 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
26	flp-5	C03G5.7	n/a	chrX 8,529,581	flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms; expressed in the sensory neurons ASE and PVM.
27	F58B4.3	F58B4.3	n/a	chrV 10,930,269	contains similarity to Homo sapiens similar to bA88M19.1 (EGF-like-domain multiple 5 protein); ENSEMBL:ENSP00000223618
28	cal-2	C18E9.1	n/a	chrII 8,961,053	cal-2 encodes a calmodulin homolog required for embryonic development or viability; CAL-2 is closely similar to its paralogs CAL-1, CAL-3, CAL-4 and CMD-1.
29	F20A1.10	F20A1.10	n/a	chrV 7,052,940
30	ttr-27	R90.2	n/a	chrV 12,903,803	C. elegans TTR-27 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
31	scl-14	F09E8.5	n/a	chrIV 13,166,113	C. elegans SCL-14 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
32	C02B8.3	C02B8.3	n/a	chrX 8,139,820
33	xbx-3	M04D8.6	n/a	chrIII 10,036,315	C. elegans XBX-3 protein ;
34	abf-5	T22H6.5	n/a	chrX 12,793,039	The abf-5 gene encodes a homolog of the antibacterial factor ASABF from Ascaris suum.
35	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
36	flp-24	C24A1.1	n/a	chrIII 725,550	C. elegans FLP-24 protein ;
37	ZK353.4	ZK353.4	n/a	chrIII 8,388,992	contains similarity to Schizosaccharomyces pombe Uncharacterized serine/threonine-rich protein PB15E9.01c precursor.; SW:Q8TFG9
38	C10G11.1	C10G11.1	n/a	chrI 6,307,930
39	ttr-21	F09F3.6	n/a	chrV 13,854,097	C. elegans TTR-21 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
40	nlp-15	CC4.2	n/a	chrI 12,991,841	C. elegans NLP-15 protein ; contains similarity to Procambarus clarkii Orcokinin peptides type A precursor [Contains: Orcomyotropin-likespeptide; Orcokinin; Orcokinin-like peptide].; SW:Q9NL83
41	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
42	K12B6.4	K12B6.4	n/a	chrV 6,280,741
43	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
44	C33G8.4	C33G8.4	n/a	chrV 7,006,530
45	M04D8.7	M04D8.7	n/a	chrIII 10,037,728	contains similarity to Sulfolobus tokodaii Putative cytochrome o ubiquinol oxidase assembly factor.; TR:Q970T4
46	nas-28	F42A10.8	n/a	chrIII 6,182,093	C. elegans NAS-28 protein; contains similarity to Pfam domain PF01400 Astacin (Peptidase family M12A) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
47	K01A2.10	K01A2.10	n/a	chrII 322,278	contains similarity to Homo sapiens Coiled-coil domain-containing protein 92; ENSEMBL:ENSP00000238156
48	C15B12.4	C15B12.4	n/a	chrX 6,472,014	contains similarity to Interpro domain IPR000158 (Cell division protein FtsZ, N-terminal)
49	T10G3.1	T10G3.1	n/a	chrV 13,471,322	contains similarity to Saccharomyces cerevisiae interacts with Sin1p; SGD:YER047C
50	R05A10.2	R05A10.2	n/a	chrIV 14,178,019	contains similarity to Saccharomyces cerevisiae Actin-binding protein that stabilizes actin filaments; Tpm1, the main tropomyosin, is required for the formation and stability of actin cables in vivo which direct polarized cell growth and the distribution of several organelles.; SGD:YNL079C