UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	M70.4	M70.4	0	chrIV 2,258,333	M70.4 is orthologous to human O-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE (FLJ20277; OMIM:606822), which when mutated leads to muscle-eye-brain disease.
2	D2005.6	D2005.6	n/a	chrI 7,790,102	contains similarity to Homo sapiens Fusion protein SYT-SSX1; ENSEMBL:ENSP00000269138
3	C06C3.9	C06C3.9	n/a	chrII 9,377,271
4	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
5	T05C1.2	T05C1.2	n/a	chrII 4,482,363
6	W05B5.1	W05B5.1	n/a	chrI 13,043,893	contains similarity to Saccharomyces cerevisiae Homolog of human WASP, proline-rich protein; SGD:YOR181W
7	C44F1.2	C44F1.2	n/a	chrIII 3,769,375	contains similarity to Pfam domains PF01342 (SAND domain) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR010919 (SAND-like), IPR000770 (SAND)
8	F21C3.6	F21C3.6	n/a	chrI 7,284,859	contains similarity to Homo sapiens Isoform 1 of Caldesmon; ENSEMBL:ENSP00000354826
9	B0207.1	B0207.1	n/a	chrI 5,966,138	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000005 (Helix-turn-helix, AraC type), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
10	Y17G7B.19	Y17G7B.19	n/a	chrII 12,110,327	contains similarity to Pfam domain PF01666 (DX module)
11	ceh-12	F33D11.4	n/a	chrI 5,841,090	ceh-12 encodes a homeobox protein orthologous to human HLXB9 (OMIM:142994, mutated in Currarino syndrome) that is required for normal synaptic inputs to motor neurons VA2-VA10 (sisters to VB3-VB11); ceh-12 is expressed in VB motor neurons, but repressed in their VA siblings by UNC-4 and UNC-37; unc-4 or unc-37 mutants show ectopic CEH-12 expression in VA neurons, which is both necessary and sufficient to induce VA neurons to form gap junctions with normally VB-specific interneurons; ceh-12 mutations have no grossly obvious phenotype, and have no effect on del-1 or acr-5 repression in VB neurons, but do suppress the backward movement defect of unc-4 mutants, and do derepress vab-7 (normally restricted to DB and VC motor neurons); CEH-12, like other HLXB9 orthologs, has an N-terminal eh1 domain that may interact with UNC-37/Groucho, and that may indicate CEH-12 to be a transcriptional repressor.
12	str-86	F59E11.14	n/a	chrV 8,983,013	C. elegans STR-86 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	col-147	T06E4.4	n/a	chrV 9,632,778	C. elegans COL-147 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
14	F26F4.8	F26F4.8	n/a	chrIII 4,904,678	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
15	H12D21.5	H12D21.5	n/a	chrV 14,894,419	contains similarity to Interpro domains IPR001307 (Thiosulfate sulfurtransferase), IPR000463 (Cytosolic fatty-acid binding protein), IPR001763 (Rhodanese-like)
16	F46B6.10	F46B6.10	n/a	chrV 9,801,717	contains similarity to Homo sapiens Hypothetical protein; TR:Q96QJ8
17	K02F6.1	K02F6.1	n/a	chrII 2,555,138	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR013084 (Zinc finger, CCHC retroviral-type), IPR001969 (Peptidase aspartic, active site), IPR001878 (Zinc finger, CCHC-type)
18	F18A12.4	F18A12.4	n/a	chrII 3,405,348	F18A12.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.4 has no clear orthologs in other organisms.
19	T11F1.2	T11F1.2	n/a	chrII 2,957,123	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
20	T09B4.3	T09B4.3	n/a	chrI 6,177,087
21	R13A1.1	R13A1.1	n/a	chrIV 7,220,097
22	ZK1098.6	ZK1098.6	n/a	chrIII 9,527,820	ZK1098.6 encodes a coiled-coil protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
23	srx-90	H12C20.5	n/a	chrV 11,581,770	C. elegans SRX-90 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
24	K10C9.7	K10C9.7	n/a	chrV 1,066,687
25	F47F6.4	F47F6.4	n/a	chrII 1,262,570
26	F46F5.11	F46F5.11	n/a	chrII 810,328	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
27	F41F3.1	F41F3.1	n/a	chrV 4,655,174
28	Y116A8C.23	Y116A8C.23	n/a	chrIV 17,054,490	contains similarity to Interpro domain IPR000694 (Proline-rich region)
29	F25B3.2	F25B3.2	n/a	chrV 9,578,510	contains similarity to Lactococcus lactis Oligopeptide transport system permease protein oppC.; SW:OPPC_LACLA
30	unc-79	E03A3.6	n/a	chrIII 4,074,729	unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with nca-1 and nca-2, which encode ion channel subunits, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of NCA-1 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults.
31	T05E11.7	T05E11.7	n/a	chrIV 11,103,651	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domains IPR004296 (Protein of unknown function DUF236), IPR005819 (Histone H5)
32	T11A5.1	T11A5.1	n/a	chrV 9,859,109	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR008162 (Inorganic pyrophosphatase)
33	nas-5	T23H4.3	n/a	chrI 9,887,167	nas-5 encodes an astacin-like metalloprotease; loss of nas-5 activity in an RNAi hypersensitive strain results in axon guidance defects, including a failure of DD/VD motoneuron commissures to reach the dorsal cord, defasciculation of the dorsal nerve cord, and midline crossing defects in the ventral nerve cord.
34	R02F11.2	R02F11.2	n/a	chrV 4,795,145
35	tbx-41	T26C11.1	n/a	chrX 1,865,937	C. elegans TBX-41 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
36	tag-19	C09G9.4	n/a	chrIV 8,875,605	tag-19 superficially resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, it is distantly related, being no closer to them than to glutamine decarboxylase/sphingosinge lyase (e.g., tag-38, spl-1); tag-19 thus might be termed a Pyridoxal-phosphate (PLP) dependent decarboxylase-like protei, but is missing the absolutely conserved Lys residue of all PLP-DCs (hence the -like would be needed); tag-19 is dispensable in mass RNAi assays.
37	C03B1.6	C03B1.6	n/a	chrX 6,350,637
38	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
39	scl-23	B0545.3	n/a	chrIV 88,065	C. elegans SCL-23 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR014044 (SCP-like extracellular)
40	R10D12.1	R10D12.1	n/a	chrV 13,933,592	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
41	T02H6.8	T02H6.8	n/a	chrII 681,180
42	try-6	F48A9.3	n/a	chrI 6,586,594	C. elegans TRY-6 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
43	fbxa-96	H03G16.4	n/a	chrX 15,059,361	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	F26A1.3	F26A1.3	n/a	chrIII 4,827,878	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
45	Y57G11C.23	Y57G11C.23	n/a	chrIV 14,858,495	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
46	F02H6.6	F02H6.6	n/a	chrIV 14,230,085	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
47	R10F2.4	R10F2.4	n/a	chrIII 2,921,110	contains similarity to Interpro domain IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal)
48	F49B2.6	F49B2.6	n/a	chrI 14,335,445	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
49	irk-1	R03E9.4	n/a	chrX 6,769,400	C. elegans IRK-1 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
50	F31B9.2	F31B9.2	n/a	chrX 15,919,200	contains similarity to Mus musculus Radixin (ESP10).; SW:RADI_MOUSE