UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srt-44	M199.1	5e-178	chrIV 15,105,017	C. elegans SRT-44 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F46F5.10	F46F5.10	n/a	chrII 824,543	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
4	Y70C5B.1	Y70C5B.1	n/a	chrV 16,662,837
5	F36D1.6	F36D1.6	n/a	chrI 11,270,696	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
6	C10G11.10	C10G11.10	n/a	chrI 6,305,695
7	F11D5.5	F11D5.5	n/a	chrX 3,302,988	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
8	ins-37	F08G2.6	n/a	chrII 13,835,294	ins-37 encodes an insulin-like peptide.
9	fbxa-224	ZK1290.9	n/a	chrII 7,547,404	fbxa-224 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
10	nhr-119	K12H6.1	n/a	chrII 2,799,024	C. elegans NHR-119 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	H12D21.5	H12D21.5	n/a	chrV 14,894,419	contains similarity to Interpro domains IPR001307 (Thiosulfate sulfurtransferase), IPR000463 (Cytosolic fatty-acid binding protein), IPR001763 (Rhodanese-like)
12	F46F5.1	F46F5.1	n/a	chrII 790,983
13	nas-5	T23H4.3	n/a	chrI 9,887,167	nas-5 encodes an astacin-like metalloprotease; loss of nas-5 activity in an RNAi hypersensitive strain results in axon guidance defects, including a failure of DD/VD motoneuron commissures to reach the dorsal cord, defasciculation of the dorsal nerve cord, and midline crossing defects in the ventral nerve cord.
14	try-6	F48A9.3	n/a	chrI 6,586,594	C. elegans TRY-6 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
15	tag-19	C09G9.4	n/a	chrIV 8,875,605	tag-19 superficially resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, it is distantly related, being no closer to them than to glutamine decarboxylase/sphingosinge lyase (e.g., tag-38, spl-1); tag-19 thus might be termed a Pyridoxal-phosphate (PLP) dependent decarboxylase-like protei, but is missing the absolutely conserved Lys residue of all PLP-DCs (hence the -like would be needed); tag-19 is dispensable in mass RNAi assays.
16	bath-25	T27C10.4	n/a	chrI 10,877,883	C. elegans BATH-25 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00036 (EF hand) (2), PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
17	ZK353.3	ZK353.3	n/a	chrIII 8,396,275
18	srz-45	Y6G8.1	n/a	chrV 17,593,282	C. elegans SRZ-45 protein; contains similarity to Interpro domain IPR002229 (Blood group Rhesus C/E and D polypeptide)
19	R04A9.1	R04A9.1	n/a	chrX 405,128
20	unc-79	E03A3.6	n/a	chrIII 4,074,729	unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with nca-1 and nca-2, which encode ion channel subunits, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of NCA-1 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults.
21	Y57G11C.23	Y57G11C.23	n/a	chrIV 14,858,495	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
22	K02D10.2	K02D10.2	n/a	chrIII 8,770,897
23	Y43F8C.9	Y43F8C.9	n/a	chrV 19,646,679	contains similarity to Dictyostelium discoideum Myb-like protein.; SW:P34127
24	T02G6.2	T02G6.2	n/a	chrI 11,801,906	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9C9Y9
25	T09B4.3	T09B4.3	n/a	chrI 6,177,087
26	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
27	F23B12.1	F23B12.1	n/a	chrV 14,429,754	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
28	C06C3.9	C06C3.9	n/a	chrII 9,377,271
29	cwp-5	F48C11.2	n/a	chrX 13,184,746	C. elegans CWP-5 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
30	fbxa-96	H03G16.4	n/a	chrX 15,059,361	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
31	Y7A5A.3	Y7A5A.3	n/a	chrX 15,783,069
32	ZC155.2	ZC155.2	n/a	chrIII 5,219,635	contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold)
33	C17D12.5	C17D12.5	n/a	chrI 11,586,755	contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like)
34	T22B2.7	T22B2.7	n/a	chrX 3,909,459
35	ttr-6	T28B4.3	n/a	chrX 6,596,773	C. elegans TTR-6 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
36	C03B1.6	C03B1.6	n/a	chrX 6,350,637
37	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
38	T27A8.4	T27A8.4	n/a	chrX 16,067,184	contains similarity to Saccharomyces cerevisiae Involved in protein transport at multiple stages of the secretory pathway; SGD:YDR170C
39	str-86	F59E11.14	n/a	chrV 8,983,013	C. elegans STR-86 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
41	ZK177.3	ZK177.3	n/a	chrII 5,516,470	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
42	lgc-30	F58H7.3	n/a	chrIV 932,249	C. elegans LGC-30 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
43	R04B5.1	R04B5.1	n/a	chrV 10,078,069	contains similarity to Culex nigripalpus baculovirus Putative 33 kDa early protein (CUN014 similar to AcMNPV ORF92).; TR:Q99GP2
44	W01B6.5	W01B6.5	n/a	chrIV 10,077,459	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif)
45	Y116A8C.19	Y116A8C.19	n/a	chrIV 17,039,245	Y116A8C.19 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y116A8C.19 is predicted to function as an RNA-binding protein.
46	F15H9.1	F15H9.1	n/a	chrI 12,157,921	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
47	gly-15	C54C8.11	n/a	chrI 12,463,985	gly-15 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; gly-15 expressed only in cellular processes that are probably part of the secretory network of the G2 gland cells.
48	Y41C4A.1	Y41C4A.1	n/a	chrIII 11,648,712	contains similarity to Oryza sativa Putative aspartate kinase.; TR:Q851Z6
49	C40D2.4	C40D2.4	n/a	chrII 2,000,282	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
50	E03H4.11	E03H4.11	n/a	chrI 12,433,962	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)