UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	col-76	M110.1	0	chrII 8,205,836	C. elegans COL-76 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	erd-2	F09B9.3	n/a	chrX 10,158,581	erd-2 encodes a protein with homology to human ER lumen protein retaining receptor 1.
4	hke-4.2	H13N06.5	n/a	chrX 15,506,879	C. elegans HKE-4.2 protein; contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domains IPR002395 (HMW kininogen), IPR003689 (Zinc/iron permease)
5	rad-23	ZK20.3	n/a	chrII 11,652,044	C. elegans RAD-23 protein; contains similarity to Pfam domains PF09280 (XPC-binding domain) , PF00627 (UBA/TS-N domain) (2), PF00240 (Ubiquitin family) contains similarity to Interpro domains IPR004806 (UV excision repair protein Rad23), IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR014761 (UV excision repair protein Rad23, C-terminal), IPR000626 (Ubiquitin), IPR009060 (UBA-like), IPR006636 (Heat shock chaperonin-binding), IPR000449 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote), IPR015360 (XPC-binding domain)
6	Y113G7B.16	Y113G7B.16	n/a	chrV 20,268,307	contains similarity to Pfam domain PF05600 Protein of unknown function (DUF773) contains similarity to Interpro domain IPR008491 (Protein of unknown function DUF773)
7	tbb-2	C36E8.5	n/a	chrIII 4,016,820	tbb-2 encodes a homolog of mammalian beta-tubulin (TUBB) that is expressed at high levels in the germline; TBB-2 is redundant for embryonic viability, due to its paralog TBB-1; however, unlike its paralog TBB-1 it is preferred for normal microtubule severing by the katanin complex MEI-1/MEI-2; TBB-2 is required together with TBB-1, TBA-1, and tba-2 to make spindle structures in embryos and TBB-2 also affects the stability of the PO spindle; first divisions are normal in null mutants, but putative gain-of-function mutations affect centrosome rotations in the P0, P1, and EMS blastomeres of the early embryo, and affect pronuclear migration and meiosis.
8	C44B7.7	C44B7.7	n/a	chrII 6,879,653	contains similarity to Homo sapiens Uncharacterized protein C7orf24; ENSEMBL:ENSP00000275428
9	Y47D3B.6	Y47D3B.6	n/a	chrIII 11,427,622	contains similarity to Pfam domain PF01683 EB module contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000480 (Glutelin), IPR006149 (Nematode-specific EB region)
10	F23C8.5	F23C8.5	n/a	chrI 2,419,472	The F23C8.5 gene encodes an ortholog of the human gene ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT (ETFB), which when mutated leads to glutaricaciduria type IIB (OMIM:130410).
11	erv-46	K09E9.2	n/a	chrX 15,615,388	C. elegans ERV-46 protein; contains similarity to Pfam domain PF07970 Protein of unknown function (DUF1692) contains similarity to Interpro domain IPR012936 (Protein of unknown function DUF1692)
12	T06D8.3	T06D8.3	n/a	chrII 11,224,333	contains similarity to Pfam domain PF01569 PAP2 superfamily contains similarity to Interpro domain IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase)
13	W08E3.2	W08E3.2	n/a	chrI 13,334,747	contains similarity to Interpro domain IPR004054 (Potassium channel, voltage dependent, Kv4.1)
14	pabp-2	C17E4.5	n/a	chrI 9,421,408	pabp-2 encodes the C. elegans PABPN1 (polyadenylate-binding protein, nuclear 1) ortholog; by homology, PABP-2 is predicted to function as a poly(A)-binding protein involved in several aspects of pre-mRNA processing; large-scale RNAi screens indicate that pabp-2 activity is essential for embryonic and larval development, as well as normal rates of growth and locomotion; in humans, expansion of a polyalanine repeat in PABPN1 is associated with oculopharyngeal muscular dystrophy (OPMD, OMIM:602279).
15	acbp-3	F47B10.7	n/a	chrX 10,904,105	acbp-3 encodes an Acyl-CoA-binding protein; a deletion mutation, tm2924, that overlaps with the 5' region of acbp-3 has been reported to result in lethality and sterility.
16	acl-8	T05H4.1	n/a	chrV 6,451,547	C. elegans ACL-8 protein; contains similarity to Pfam domain PF01553 Acyltransferase contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
17	dnj-13	F54D5.8	n/a	chrII 11,546,449	This gene encodes a protein containing a DnaJ ('J') domain.
18	T19D12.1	T19D12.1	n/a	chrII 6,670,282	contains similarity to Drosophila melanogaster Flybase gene name is Sgs1-PA;; FLYBASE:CG3047
19	stc-1	F54C9.2	n/a	chrII 8,564,862	C. elegans STC-1 protein; contains similarity to Pfam domain PF00012 Hsp70 protein contains similarity to Interpro domains IPR001023 (Heat shock protein Hsp70), IPR013126 (Heat shock protein 70)
20	cogc-6	K07C11.9	n/a	chrV 8,219,777	cogc-6 encodes an ortholog of mammalian COG-6, a subunit of lobe B of the conserved oligomeric Golgi complex (COGC); COGC-6 is weakly required for normal gonadal distal tip cell migration, a process that also requires seven other orthologs of COGC subunits; like other lobe B subunits in both C. elegans and S. cerevisiae, COGC-6 is only partially required for normal function, while lobe A subunits are strongly required in either worms or yeast.
21	ZK686.3	ZK686.3	n/a	chrIII 7,768,245	ZK686.3 is orthologous to the putative tumor suppressor N33 (OMIM:601385, associated with homozygous deletion in metastatic prostate cancer and with loss of function in other tumors); ZK686.3 is also homologous to the S. cerevisiae dolichyl-diphosphooligosaccharide-protein glycotransferase gamma chain (34-kD) subunit, OST3.
22	W09D10.3	W09D10.3	n/a	chrIII 10,708,021	contains similarity to Pfam domain PF00542 Ribosomal protein L7/L12 C-terminal domain contains similarity to Interpro domains IPR013823 (Ribosomal protein L7/L12, C-terminal), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR008932 (Ribosomal protein L7/L12, oligomerisation)
23	C03H12.1	C03H12.1	n/a	chrX 15,692,830	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
24	F38E11.5	F38E11.5	n/a	chrIV 9,461,841	F38E11.5 encodes a beta' (beta-prime) subunit of the coatomer (COPI) complex; in mass RNAi assays, F38E11.5 is required for fertility and general health.
25	B0272.3	B0272.3	n/a	chrX 9,432,002	contains similarity to Pfam domains PF00725 (3-hydroxyacyl-CoA dehydrogenase, C-terminal domain) , PF02737 (3-hydroxyacyl-CoA dehydrogenase, NAD binding domain) contains similarity to Interpro domains IPR013328 (Dehydrogenase, multihelical), IPR008927 (6-phosphogluconate dehydrogenase, C-terminal-like), IPR006176 (3-hydroxyacyl-CoA dehydrogenase, NAD binding), IPR006168 (NAD-dependent glycerol-3-phosphate dehydrogenase), IPR006108 (3-hydroxyacyl-CoA dehydrogenase, C-terminal), IPR006180 (3-hydroxyacyl-CoA dehydrogenase, conserved site), IPR016040 (NAD(P)-binding), IPR006036 (Potassium uptake protein TrkA)
26	K08F11.5	K08F11.5	n/a	chrIV 4,714,405	contains similarity to Pfam domains PF08356 (EF hand associated) , PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) (2), PF08477 (Miro-like protein) (2)contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily), IPR013567 (EF hand associated, type-2)
27	F25B4.6	F25B4.6	n/a	chrV 5,683,638	F25B4.6 is orthologous to the human gene 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE (HMGCS2; OMIM:600234), which when mutated leads to disease.
28	abu-8	C03A7.14	n/a	chrV 5,193,784	abu-8 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-8 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-8 may help protect the organism from damage by improperly folded nascent protein.
29	C29F7.2	C29F7.2	n/a	chrX 13,417,071	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
30	B0334.5	B0334.5	n/a	chrII 11,498,118	contains similarity to Interpro domain IPR008949 (Terpenoid synthase)
31	rnp-5	K02F3.11	n/a	chrIII 853,412	rnp-5 encodes a putative member of the exon-exon junction complex, orthologous to human RNPS1 (OMIM:606447); RNP-5 is dispensable for embryonic viability.
32	gstk-1	ZK1320.1	n/a	chrII 9,657,127	C. elegans GSTK-1 protein; contains similarity to Pfam domain PF01323 DSBA-like thioredoxin domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001853 (DSBA oxidoreductase), IPR014440 (HCCA isomerase/glutathione S-transferase kappa)
33	nhr-68	H12C20.3	n/a	chrV 11,574,552	C. elegans NHR-68 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	W03F9.10	W03F9.10	n/a	chrV 129,988	contains similarity to Pfam domains PF04046 (PSP) , PF04037 (Domain of unknown function (DUF382)) contains similarity to Interpro domains IPR006568 (PSP, proline-rich), IPR007180 (Protein of unknown function DUF382)
35	sft-4	C54H2.5	n/a	chrX 5,779,970	sft-4 encodes a member of the SURF family highly conserved with the mouse Surf-4 gene, and conservation includes an encoded dilysine motif that is implicated in endoplasmic reticulum localization of the mouse protein.
36	K01A2.5	K01A2.5	n/a	chrII 303,020	contains similarity to Pfam domain PF00561 alpha/beta hydrolase fold contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR003089 (Alpha/beta hydrolase)
37	tag-231	ZK430.2	n/a	chrII 4,421,285	C. elegans TAG-231 protein; contains similarity to Pfam domain PF00459 Inositol monophosphatase family contains similarity to Interpro domains IPR000760 (Inositol monophosphatase), IPR000146 (Inositol phosphatase/fructose-1,6-bisphosphatase)
38	K10C2.1	K10C2.1	n/a	chrX 6,425,780	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001563 (Peptidase S10, serine carboxypeptidase)
39	C08H9.2	C08H9.2	n/a	chrII 9,888,735	contains similarity to Pfam domain PF00013 KH domain contains similarity to Interpro domains IPR004087 (K Homology), IPR004088 (K Homology, type 1)
40	ugt-21	C33A12.6	n/a	chrIV 9,501,385	C. elegans UGT-21 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
41	alh-9	F01F1.6	n/a	chrIII 5,858,031	C. elegans ALH-9 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
42	ile-2	T04G9.3	n/a	chrX 769,684	C. elegans ILE-2 protein; contains similarity to Pfam domains PF03388 (Legume-like lectin family) , PF00139 (Legume lectin domain) contains similarity to Interpro domains IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR001220 (Legume lectin, beta domain), IPR005052 (Legume-like lectin), IPR008985 (Concanavalin A-like lectin/glucanase)
43	C06A8.3	C06A8.3	n/a	chrII 7,790,994	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
44	odc-1	K11C4.4	n/a	chrV 6,899,252	odc-1 encodes ornithine decarboxylase, the first enzyme of polyamine biosynthesis that catalyzes the conversion of ornithine to putrescine; ODC-1 is required for development when animals are deprived of exogenous polyamines, which are required for oogenesis and completion of embryogenesis; in addition,ODC-1 may contribute to male fertility; ODC-1 activity is detectable at all developmental stages, with highest levels observed in adults and L4 larvae.
45	ZK682.5	ZK682.5	n/a	chrV 9,285,827	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR000480 (Glutelin)
46	C47C12.4	C47C12.4	n/a	chrX 7,757,369	contains similarity to Pfam domains PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
47	F53A2.7	F53A2.7	n/a	chrIII 13,345,704	contains similarity to Pfam domains PF02803 (Thiolase, C-terminal domain) , PF00108 (Thiolase, N-terminal domain) contains similarity to Interpro domains IPR016038 (Thiolase-like, subgroup), IPR002155 (Thiolase), IPR016039 (Thiolase-like)
48	F53F1.5	F53F1.5	n/a	chrV 13,415,573	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001859 (Ribosomal protein P2), IPR013286 (Annexin, type VII)
49	F27D4.1	F27D4.1	n/a	chrI 7,703,501	The F27D4.1 gene encodes an ortholog of the human gene ELECTRON-TRANSFER-FLAVOPROTEIN, ALPHA POLYPEPTIDE (ETFA), which when mutated leads to glutaricaciduria type IIA (OMIM:231680).
50	pqn-47	F59B10.1	n/a	chrII 10,499,684	pqn-47 encodes a protein with a glutamine/asparagine-rich domain, homologous to human C11orf9 and Drosophila CG3328, that is required for locomotion, vulval development, full body size, cuticular integrity, and general health in mass RNAi assays; pqn-47(cxP5915) homozygotes are sluggish.